Silencing UHRF1 Inhibits Cell Proliferation and Promotes Cell Apoptosis in Retinoblastoma Via the PI3K/Akt Signalling Pathway

UHRF1 depletion sensitizes retinoblastoma cells to chemotherapeutic drugs via downregulation of XRCC4

(2018) Heng He et al.   Cell Death & Disease

Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulation

(2017) Maike Busch et al.   INTERNATIONAL JOURNAL OF CANCER

UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis

(2017) Bing Wang et al.   OncoTargets and Therapy

Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome

(2017) Guangyan Kan et al.   Oncotarget

Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): inhibition of bladder cancer cell aggressiveness

(2016) Ryosuke Matsushita et al.   Oncotarget

Uhrf1 Controls iNKT Cell Survival and Differentiation through the Akt-mTOR Axis

(2016) Yu Cui et al.   Cell Reports

Retinoblastoma

(2015) Helen Dimaras et al.   Nature Reviews Disease Primers

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters

(2015) Dong Hyun Jo et al.   Oncotarget

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression

(2015) Claudia A. Benavente et al.   Oncotarget

BIRO1, a Cell-Permeable BH3 Peptide, Promotes Mitochondrial Fragmentation and Death of Retinoblastoma Cells

(2014) Nathalie Allaman-Pillet et al.   MOLECULAR CANCER RESEARCH

UHRF1 depletion suppresses growth of gallbladder cancer cells through induction of apoptosis and cell cycle arrest

(2014) YIYU QIN et al.   ONCOLOGY REPORTS

A population-based study of retinoblastoma incidence and survival in Argentine children

(2014) Florencia Moreno et al.   PEDIATRIC BLOOD & CANCER

Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies

(2013) Diane E Rushlow et al.   LANCET ONCOLOGY

A novel retinoblastoma therapy from genomic and epigenetic analyses

(2012) Jinghui Zhang et al.   NATURE

Synthesis and evaluation of nucleoside radiotracers for imaging proliferation

(2012) Graham Smith et al.   NUCLEAR MEDICINE AND BIOLOGY

Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway

(2012) HONG-BO ZHANG et al.   Oncology Letters

Intra-arterial Chemotherapy for Retinoblastoma

(2011) Carol L. Shields   ARCHIVES OF OPHTHALMOLOGY

UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis

(2011) Amy L. Tien et al.   BIOCHEMICAL JOURNAL

Gene therapy with RNAi targeting UHRF1 driven by tumor-specific promoter inhibits tumor growth and enhances the sensitivity of chemotherapeutic drug in breast cancer in vitro and in vivo

(2011) Lin Fang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor

(2011) Tsutomu Mori et al.   CELL CYCLE

UHRF1 is a novel diagnostic marker of lung cancer

(2010) M Unoki et al.   BRITISH JOURNAL OF CANCER

Genetic Alterations in the Phosphoinositide 3-Kinase/Akt Signaling Pathway Confer Sensitivity of Thyroid Cancer Cells to Therapeutic Targeting of Akt and Mammalian Target of Rapamycin

(2009) D. Liu et al.   CANCER RESEARCH

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

(2008) Jong Kyong Kim et al.   NUCLEIC ACIDS RESEARCH