Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway
出版年份 2019 全文链接
标题
Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway
作者
关键词
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出版物
Oxidative Medicine and Cellular Longevity
Volume 2019, Issue -, Pages 1-19
出版商
Hindawi Limited
发表日期
2019-04-29
DOI
10.1155/2019/1958941
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Compound K Inhibits Autophagy-Mediated Apoptosis Through Activation of the PI3K-Akt Signaling Pathway Thus Protecting Against Ischemia/Reperfusion Injury
- (2018) Xiangyan Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7
- (2018) Xin‑Long Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- MicroRNA-410 inhibition of the TIMP2-dependent MAPK pathway confers neuroprotection against oxidative stress-induced apoptosis after ischemic stroke in mice
- (2018) Ning-Ning Liu et al. BRAIN RESEARCH BULLETIN
- Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle
- (2018) Hilda Merino et al. Oxidative Medicine and Cellular Longevity
- A New Era of Cardiac Cell Therapy: Opportunities and Challenges
- (2018) Ke Huang et al. Advanced Healthcare Materials
- Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4
- (2016) Jianbing Zhu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Exosomes Derived fromAkt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D
- (2016) Jie Ma et al. Stem Cells Translational Medicine
- The Blockade of Transmembrane Cl- Flux Mitigates I/R-Induced Heart Injury via the Inhibition of Calpain Activity
- (2015) Jian-Ying Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cells
- (2015) Han Ie Kim et al. Oncotarget
- Human Umbilical Cord Mesenchymal Stem Cell Exosomes Enhance Angiogenesis Through the Wnt4/β-Catenin Pathway
- (2015) Bin Zhang et al. Stem Cells Translational Medicine
- Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury
- (2015) Yuanyuan Zhao et al. Stem Cells International
- TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis
- (2015) Cristina Valacca et al. PLoS One
- Hypoxic Conditioned Medium from Human Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Skin Wound Healing through TGF-β/SMAD2 and PI3K/Akt Pathways
- (2014) Eun Jun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention
- (2013) Michalis Mastri et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Regulation of antioxidant system, lipids and fatty acid β-oxidation contributes to the cardioprotective effect of sodium tanshinone IIA sulphonate in isoproterenol-induced myocardial infarction in rats
- (2013) Bo Wei et al. ATHEROSCLEROSIS
- miR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling
- (2013) Shu-Hong Li et al. FASEB JOURNAL
- Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
- (2013) Suyan Bian et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
- (2013) Fatih Arslan et al. Stem Cell Research
- Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
- (2012) Alexander V. Vlassov et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Cardiac stem cell therapy to modulate inflammation upon myocardial infarction
- (2012) F. van den Akker et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy
- (2012) Joshua M. Hare et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial
- (2012) Raj R Makkar et al. LANCET
- Lack of Tissue Inhibitor of Metalloproteinases 2 Leads to Exacerbated Left Ventricular Dysfunction and Adverse Extracellular Matrix Remodeling in Response to Biomechanical Stress
- (2011) Vijay Kandalam et al. CIRCULATION
- Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1
- (2011) Brian Hynes et al. EUROPEAN HEART JOURNAL
- Tissue inhibitor of metalloproteinases (TIMPs) in heart failure
- (2011) Linn Moore et al. HEART FAILURE REVIEWS
- TIMP2 Deficiency Accelerates Adverse Post–Myocardial Infarction Remodeling Because of Enhanced MT1-MMP Activity Despite Lack of MMP2 Activation
- (2010) Vijay Kandalam et al. CIRCULATION RESEARCH
- sFRP2 Suppression of Bone Morphogenic Protein (BMP) and Wnt Signaling Mediates Mesenchymal Stem Cell (MSC) Self-renewal Promoting Engraftment and Myocardial Repair
- (2010) Maria P. Alfaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exosomes/microvesicles as a mechanism of cell-to-cell communication
- (2010) Giovanni Camussi et al. KIDNEY INTERNATIONAL
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure*
- (2010) Srikanth Givvimani et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- TIMPs and cardiac remodeling: ‘Embracing the MMP-independent-side of the family’
- (2009) Davy Vanhoutte et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Improving outcome of transplanted mesenchymal stem cells for ischemic heart disease
- (2008) Rui-Zhen Shi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The anti-apoptotic effect of IGF-1 on tissue resident stem cells is mediated via PI3-kinase dependent secreted frizzled related protein 2 (Sfrp2) release
- (2008) Sebastian Gehmert et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair
- (2008) M. P. Alfaro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
- (2008) Leo Timmers et al. Stem Cell Research
- Immune Properties of Human Umbilical Cord Wharton's Jelly-Derived Cells
- (2008) Mark L. Weiss et al. STEM CELLS
- Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease
- (2007) Joseph D. Raffetto et al. BIOCHEMICAL PHARMACOLOGY
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