Article
Health Care Sciences & Services
M. Rifqi Rokhman, Yulia Wardhani, Dwi Lestari Partiningrum, Barkah Djaka Purwanto, Ika Ratna Hidayati, Arofa Idha, Jarir At Thobari, Maarten J. Postma, Cornelis Boersma, Jurjen van der Schans
Summary: This study evaluated the psychometric properties of KDQOL-36 Bahasa Indonesia in hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) patients in Indonesia. The results showed that the instrument has good validity and reliability, making it suitable for assessing the quality of life in these patients.
QUALITY OF LIFE RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Monira Alwhaibi, Bander Balkhi, Yazed AlRuthia
Summary: This study investigated the relationship between anxiety and depression and health-related quality of life (HRQoL) in adults with migraines. The findings showed that a significant proportion of migraineurs also experienced depression and anxiety, which were negatively associated with HRQoL. Migraineurs with comorbid depression and anxiety had the lowest HRQoL scores. Furthermore, regular exercise was found to have a positive impact on HRQoL among migraine sufferers.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Axel Svedbom, Fredrik Borgstom, Emma Hernlund, Vidmantas Alekna, Maria Luisa Bianchi, Patricia Clark, Manuel Diaz-Curiel, Hans Peter Dimai, Mikk Jurisson, Olga Lesnyak, Eugene McCloskey, Kerrie M. Sanders, Stuart Silverman, Marija Tamulaitiene, Thierry Thomas, Anna N. A. Tosteson, Bengt Jonsson, John A. Kanis
Summary: This study derived an experience- and preference-based value set for EQ-5D-3L from a prospective observational study, rather than the commonly used hypothetical value sets. The study found that the experience-based value set had better face validity compared to other hypothetical value sets.
QUALITY OF LIFE RESEARCH
(2023)
Article
Obstetrics & Gynecology
Naama Peltz-Sinvani, Hadar Milloh Raz, Pinchas Klein, Sophia Ish-Shalom, Iris Vered, Liana Tripto-Shkolnik
Summary: This study aimed to identify the clinical parameters, risk factors, and osteoporosis-related quality of life (QOL) in women with pregnancy- and lactation-induced osteoporosis (PLO). The survey results showed that most PLO patients reported multiple vertebral fractures, delayed diagnosis, and treatment with teriparatide. Compared to the control group, the PLO group reported less physical activity and impaired QOL.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Medicine, General & Internal
Miyuna Kimura, Junji Yamauchi, Tomoo Sato, Naoko Yagishita, Natsumi Araya, Satoko Aratani, Kenichiro Tanabe, Erika Horibe, Toshiki Watanabe, Ariella Coler-Reilly, Misako Nagasaka, Yukari Akasu, Kei Kaburagi, Takayuki Kikuchi, Soichiro Shibata, Hirofumi Matsumoto, Akihito Koseki, Soichiro Inoue, Ayako Takata, Yoshihisa Yamano
Summary: This study aimed to reveal the impact of human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) on health-related quality of life (HRQoL). The results showed that HRQoL of patients with HAM was worse than that of the general population and was associated with all major symptoms.
FRONTIERS IN MEDICINE
(2022)
Article
Geriatrics & Gerontology
Xiaofeng Xu, Qixiang Zheng, Siying Wei, Yongmei Chen, Xiuying Hu
Summary: This study conducted a half-year follow-up survey on elderly patients with bone trauma to clarify their quality of life (QoL) and its influencing factors. The results showed that the QoL gradually improved after the injury, but the recovery time was long and the influencing factors were complex.
Article
Endocrinology & Metabolism
Ya-Ping Huang, Li-Sheng Chen, Shih-Hao Feng, Yu-Shiuan Liang, Shin-Liang Pan
Summary: This population-based longitudinal follow-up study found that tea consumption is associated with a lower risk of osteoporosis and hip fracture. The protective effect is particularly significant for women and middle-aged people.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Health Care Sciences & Services
Dongyeop Kim, Jee Hyun Kim, Tae-Jin Song
Summary: This study found that variability in serum total cholesterol (TC) is associated with the risk of osteoporotic fractures. Higher TC variability was significantly associated with an increased risk of overall osteoporotic fractures, as well as vertebral and hip fractures. Maintaining stable TC levels may help reduce the risk of osteoporotic fractures in the future.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Orthopedics
Marziyeh Rajabi, Afshin Ostovar, Ali Akbari Sari, Sayed Mahmoud Sajjadi-Jazi, Noushin Fahimfar, Bagher Larijani, Rajabali Daroudi
Summary: This study estimated the direct costs of hip, vertebral, and forearm fractures in the first year after fracture incidence in Iran, finding that the direct cost of osteoporotic fractures in Iran is high. The findings may be useful for economic evaluation and estimating the economic burden of osteoporotic fractures in Iran.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Endocrinology & Metabolism
Gregory A. Kline, Suzanne N. Morin, Lisa M. Lix, William D. Leslie
Summary: This study examined medication adherence in women with osteoporosis before and after a fracture. The results show that many women experience a decline in medication adherence after a fracture, which is paradoxical to expectations. Fracture on therapy represents an important opportunity for clinicians to emphasize treatment adherence.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Oncology
Preston J. Ngo, Stephen Wade, Pavla Vaneckova, Silvia Behar Harpaz, Michael Caruana, Sonya Cressman, Martin Tammemagi, Deme Karikios, Karen Canfell, Marianne F. Weber
Summary: This study estimated the utility values of high-risk individuals for lung cancer screening and found that their average health utility values were lower compared to population norms.
Article
Oncology
Inna Y. Y. Gong, Kelvin K. W. Chan, Lorraine L. Lipscombe, Matthew C. Cheung, Lee Mozessohn
Summary: Patients with cancer have a higher risk of fractures compared to non-cancer controls.
BRITISH JOURNAL OF CANCER
(2023)
Article
Geriatrics & Gerontology
Pluvio J. Coronado, Manuel Monroy, Maria Fasero, Rafael Sanchez-Borrego, Santiago Palacios, Javier Rejas, Miguel A. Ruiz
Summary: This study developed population-based norms for the Cervantes-SF scale, which measures the impact of menopause on the health-related quality of life (HRQOL) of women in Spain. The results showed a gradual increase in the impact of menopause on HRQOL as age increases, with significant differences in symptomatology and HRQOL impact among different age groups, as well as various factors such as generic HRQOL, comorbidities, history of osteoporotic fractures, educational level, and obesity.
Article
Geriatrics & Gerontology
Warrington W. Q. Hsu, Xiaowen Zhang, Chor-Wing Sing, Gloria H. Y. Li, Kathryn C. B. Tan, Annie W. C. Kung, Janus S. H. Wong, Ian Chi-Kei Wong, Ching-Lung Cheung
Summary: The study found that hip fracture was associated with an increased risk of dementia among older adults, especially in women. Further research on the potential role of hip fracture in the development of dementia could benefit the management of both conditions in older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Health Care Sciences & Services
Monira Alwhaibi
Summary: This study investigates the relationship between anxiety, depression, and health-related quality of life (HRQoL) in individuals with gastroesophageal reflux disease (GERD). The results show that GERD patients with anxiety, depression, or both have significantly worse HRQoL compared to those without these comorbidities. The study also highlights the detrimental impacts of co-occurring chronic illnesses and low socioeconomic status, as well as the positive benefits of employment and exercise on HRQoL.
Letter
Rheumatology
Louis Bessette, Cassandra D. Kinch
JOURNAL OF RHEUMATOLOGY
(2023)
Article
Health Care Sciences & Services
Susan J. Bartlett, Vivian P. Bykerk, Orit Schieir, Marie-France Valois, Janet E. Pope, Gilles Boire, Carol Hitchon, Glen Hazlewood, Louis Bessette, Edward Keystone, Carter Thorne, Diane Tin, Clifton O. Bingham
Summary: This study investigated the perception of disease activity change in rheumatoid arthritis (RA) patients and physicians, and estimated minimal and meaningful change thresholds. The results showed that the thresholds varied depending on the anchor used. These findings provide guidance for the assessment and decision-making in the management of RA.
QUALITY OF LIFE RESEARCH
(2023)
Article
Endocrinology & Metabolism
Andy K. O. Wong, Hugo J. W. Fung, Adrian C. H. Chan, Eva Szabo, Sunita Mathur, Lora Giangregorio, Angela M. Cheung
Summary: This cross-sectional study found that greater peak torque and higher myotendinous density at the ankle are associated with a more plate-like architecture at the distal tibia. Additionally, the strength of muscles around the ankle is correlated with plate-like trabeculae at the distal tibia.
Article
Endocrinology & Metabolism
Ifaz T. Haider, Lindsay L. Loundagin, Andrew Sawatsky, Paul J. Kostenuik, Steven K. Boyd, W. Brent Edwards
Summary: This study quantified the relationship between antiresorptive treatment and fatigue life in bone from ovariectomized cynomolgus monkeys. The results showed that the antiresorptive treatment groups had higher fatigue-life measurements and improved bone microstructure and composition compared to the control group. Therefore, antiresorptive treatment may have a protective effect against fatigue fractures.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Elina Gunsing, Philippe P. P. Wagner, Danielle E. E. Whittier, Steven K. K. Boyd, Roland Chapurlat, Pawel Szulc
Summary: Rapid cortical bone loss at the distal radius is associated with a higher risk of fracture in older men. However, repeated HR-pQCT measurements did not improve the assessment of fracture risk.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Danielle E. Whittier, Elizabeth J. Samelson, Marian T. Hannan, Lauren A. Burt, David A. Hanley, Emmanuel Biver, Pawel Szulc, Elisabeth Sornay-Rendu, Blandine Merle, Roland Chapurlat, Eric Lespessailles, Andy Kin On Wong, David Goltzman, Sundeep Khosla, Serge Ferrari, Mary L. Bouxsein, Douglas P. Kiel, Steven K. Boyd
Summary: This study developed a fracture risk assessment tool based on high-resolution peripheral quantitative compute tomography (HR-pQCT) to evaluate patient-specific fracture risk. The tool, called mu FRAC, outperformed the current Fracture Risk Assessment Tool (FRAX) and models based on bone mineral density (BMD). It provides an alternative approach by utilizing direct measures of bone density and structure.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Efthymios Papadopoulos, Andy Kin On Wong, Sharon Hiu Ching Law, Lindsey Ze Jing Zhang, Henriette Breunis, Urban Emmenegger, Shabbir M. H. Alibhai
Summary: This study comprehensively assessed sarcopenia in men with metastatic castrate-resistant prostate cancer by using CT scans and measures of muscle function. The results showed that baseline sarcopenia predicts radiographic progression and overall mortality, and may also predict severe treatment toxicity and emergency room visits.
Article
Rheumatology
Louis Bessette, Mohammad Movahedi, George Reed, Joel M. Kremer, Kevin Kane, Edward Keystone
Summary: This study evaluated the response to a second TNFi or non-TNFi in patients failing their initial TNFi treatment. The results showed that patients with secondary failure were more likely to achieve treatment goals compared to patients with primary failure, regardless of the choice of second treatment.
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
(2023)
Article
Endocrinology & Metabolism
Lauren A. Burt, Martin Kaufmann, Marianne S. Rose, Glenville Jones, Emma O. Billington, Steven K. Boyd, David A. Hanley
Summary: This randomized controlled trial investigated the effect of high-dose vitamin D-3 on total bone mineral density (TtBMD) in the radius and tibia. The study found that increasing vitamin D dose was associated with increased plasma levels of 25-(OH)D-3, 24,25-(OH)(2)D-3, and 1,24,25-(OH)(3)D-3, but not 1,25-(OH)(2)D-3. These vitamin D metabolites were associated with a decline in TtBMD. The findings suggest that vitamin D metabolites other than 1,25-(OH)(2)D-3 may play a role in bone loss.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Paige M. Wyatt, Kelly Drager, Erik M. Groves, Trent Stellingwerff, Emma O. Billington, Steven K. Boyd, Lauren A. Burt
Summary: The importance of relative energy deficiency in sports (REDs). A study investigated the differences in bone quality between low-risk and at-risk winter endurance athletes for REDs. The results showed that athletes at higher risk had lower bone quality, indicating the negative impact of REDs on athletes' health and performance.
CALCIFIED TISSUE INTERNATIONAL
(2023)
Correction
Rheumatology
R. Fleischmann, E. Mysler, L. Bessette
Article
Rheumatology
Walter P. Maksymowych, Robert D. Inman, Louis Bessette, Proton Rahman, Emmanouil Rampakakis, Odalis Asin-Milan, Meagan Rachich, Anne Marilise Marrache, Allen J. Lehman
Summary: A study found that sustained disease activity states, as measured by BASDAI and ASDAS, impact function in axial spondyloarthritis patients. Characteristics predicting sustained low functional impairment were evaluated in this prospective cohort study.
ARTHRITIS RESEARCH & THERAPY
(2023)
Article
Biology
Tannis D. Kemp, Bryce A. Besler, Leigh Gabel, Steven K. Boyd
Summary: This study uses numerical methods to estimate changes in astronaut bone health during spaceflight and recovery on Earth. The results show reasonable fit between the modeled and observed bone morphometry, Dice coefficient, and symmetric distance. However, the estimation of dynamic bone morphometry is poor.
Article
Rheumatology
Louis Bessette, Boulos Haraoui, Emmanouil Rampakakis, Joanna Dembowy, Marc-Olivier Trepanier, Janet Pope
Summary: A study compared the effects of a treat-to-target approach and routine care in patients with rheumatoid arthritis and found that treat-to-target approach resulted in faster achievement of therapeutic goals.
ARTHRITIS RESEARCH & THERAPY
(2023)
Meeting Abstract
Rheumatology
Louis Bessette, Proton Rahman, John Kelsall, Jane Purvis, Emmanouil Rampakakis, Allen J. Lehman, Meagan Rachich, Francois Nantel, A. Marilise Marrache, Odalis Asin-Milan
ARTHRITIS & RHEUMATOLOGY
(2022)