Article
Medicine, General & Internal
Liliana Gozar, Claudiu Marginean, Andreea Cerghit Paler, Dorottya Gabor-Miklosi, Daniela Toma, Mihaela Iancu, Rodica Toganel, Amalia Fagarasan
Summary: The study compared speckle-tracking peak global longitudinal (pGLS) and regional strain values in neonates with coarctation of aorta among control groups. Significant differences were found in segmental strain values at various segments of the heart, with pGLS also showing a significant difference between the studied groups. ROC analysis indicated that pGLS can be used as a reliable parameter for diagnosing CoA in neonates.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Oncology
Grzegorz Slawinski, Maja Hawryszko, Aleksandra Lizewska-Springer, Izabela Nabialek-Trojanowska, Ewa Lewicka
Summary: The assessment of global longitudinal strain (GLS) plays a crucial role in the early diagnosis of anticancer treatment-related cardiotoxicity in cardio-oncology. Baseline left ventricular (LV) GLS and right ventricular (RV) GLS assessments can identify patients at risk for systolic dysfunction and heart failure. Serial echocardiography with GLS assessment should be performed during anticancer therapy to promptly initiate and adjust cardioprotection for subclinical myocardial contractile dysfunction.
Article
Cardiac & Cardiovascular Systems
Lin Na, Wenjing Cui, Xinqi Li, Jing Chang, Xin Xue
Summary: Using speckle tracking technology, this study investigated the effect of hypertriglyceridemia on the global longitudinal strain of the left ventricle in early stage coronary heart disease patients, and explored the value of myocardial strain in early identification of cardiac dysfunction. A cross-sectional study of 138 participants was conducted, and the myocardial strain parameters were compared between hypertriglyceridemia and normal triglyceride level groups, evaluating the effect of hypertriglyceridemia on early left ventricular global longitudinal strain impairment in coronary heart disease patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Cristhian H. Aristizabal-Duque, Juan Fernandez Cabeza, Isabel Maria Blancas Sanchez, Monica Delgado Ortega, Pilar Aparicio Martinez, Manuel Romero-Saldana, Francisco Javier Fonseca del Pozo, Manuel Pan, Martin Ruiz Ortiz, Maria Dolores Mesa-Rubio
Summary: This study provides strain values in a healthy paediatric Spanish population and evaluates the feasibility and reproducibility of a new strain software analysis in this setting.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Christine Meindl, Michael Paulus, Florian Poschenrieder, Florian Zeman, Lars S. Maier, Kurt Debl
Summary: In patients with acute myocarditis and preserved LVEF, a significant reduction of GLS was detected compared to healthy subjects, particularly in the lateral, inferolateral, and inferior segments. Additionally, RLS values provided important information about the localization and extent of myocardial injury, especially in segments without LGE.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Flemming Javier Olsen, Sofie Reumert Biering-Sorensen, Anne Marie Reimer Jensen, Peter Schnohr, Gorm Boje Jensen, Jesper Hastrup Svendsen, Rasmus Mogelvang, Tor Biering-Sorensen
Summary: Global longitudinal strain can predict atrial fibrillation in individuals without hypertension from the general population, independently of common risk scores.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Review
Multidisciplinary Sciences
Denio A. Ridjab, Ignatius Ivan, Fanny Budiman, Riki Tenggara
Summary: Global longitudinal strain (GLS) can identify subclinical myocardial dysfunction in patients with cirrhosis. This systematic review found that cirrhosis is associated with reduced left ventricular and right ventricular GLS values, and the severity of cirrhosis is related to GLS reduction.
Review
Medicine, General & Internal
Sergio Alejandro Gomez-Ochoa, Lyda Z. Rojas, Juliana Alexandra Hernandez-Vargas, Jorge Largo, Taulant Muka, Luis E. Echeverria
Summary: This systematic review analyzed the left ventricular longitudinal strain patterns using speckle tracking in different stages of Chagas disease. The study found that patients with chronic Chagas cardiomyopathy had significantly higher mean global longitudinal strain values compared to those with the indeterminate form, while no significant difference was observed between the indeterminate form patients and healthy controls. Segmental strain analyses showed that patients with the indeterminate form had worse strain values in certain segments compared to healthy controls.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Federica Ilardi, Antonello D'Andrea, Flavio D'Ascenzi, Francesco Bandera, Giovanni Benfari, Roberta Esposito, Alessandro Malagoli, Giulia Elena Mandoli, Ciro Santoro, Vincenzo Russo, Mario Crisci, Giovanni Esposito, Matteo Cameli
Summary: Left ventricular global longitudinal strain (GLS) and non-invasive myocardial work (MW) quantification are two new methods for assessing myocardial function, able to overcome limitations of previous methods and provide a more reliable evaluation of myocardial performance without load dependency.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shirui Lu, Xin Hu, Jun Zhang, Ying Zhu, Wei Zhou, Yani Liu, Youbin Deng
Summary: Post-systolic shortening (PSS) is an independent predictor for adverse events in stable coronary artery disease (CAD) patients with preserved systolic function, and its prognostic value may be superior to global longitudinal strain (GLS) in patients with normal or mildly reduced GLS.
INSIGHTS INTO IMAGING
(2022)
Article
Acoustics
Serina Takeda, Toshihiko Asanuma, Kasumi Masuda, Satoshi Nakatani
Summary: The parameter FRe/SRe may provide a more accurate estimation of left ventricular filling pressure in dilated systolic failing hearts compared to E/e', as it can be obtained without the use of Doppler and showed higher correlation coefficients with LV end-diastolic pressure in a study involving dogs with decompensated heart failure.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Medicine, General & Internal
Owen Battel, Kevin Newsome, Guillermo Izquierdo-Pretel
Summary: This case illustrates the utility of GLS as an additional prognostic marker for cardiovascular complications in patients with HCM, highlighting the potential need for anticoagulation therapy and implantable cardioverter defibrillator placement. Therefore, GLS plays a crucial role in improving clinical management and prognosis.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Review
Medicine, General & Internal
Michal Laufer-Perl, Dan Gilon, Livia Kapusta, Zaza Iakobishvili
Summary: This article reviews the role of two-dimensional speckle tracking echocardiography in diagnosing early subclinical cardiac injury in patients undergoing cancer therapies, emphasizing the prevention of interference with optimal cancer therapy and the development of irreversible cardiac dysfunction.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Ying Gao, He Li, Lin He, Yanting Zhang, Wei Sun, Meng Li, Lang Gao, Yixia Lin, Mengmeng Ji, Qing Lv, Jing Wang, Li Zhang, Mingxing Xie, Yuman Li
Summary: Both RVFWLS and RVGLS can predict adverse outcomes in patients with r-TOF, but RVFWLS provides superior prognostic value than that of RVGLS.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Veterinary Sciences
Takahiro Saito, Ryohei Suzuki, Yunosuke Yuchi, Haru Fukuoka, Shuji Satomi, Takahiro Teshima, Hirotaka Matsumoto
Summary: In recent years, hypertrophic cardiomyopathy (HCM) in cats has become more common due to improvements in diagnostic techniques. This study compared myocardial function in HCM-affected cats with and without left ventricular outflow tract obstruction (DLVOTO) using speckle-tracking echocardiography. The results showed that LV myocardial function was more compromised in HCM-affected cats with DLVOTO, indicating the importance of DLVOTO in affecting LV function in HCM-affected cats.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Eigir Einarsen, Dana Cramariuc, Edda Bahlmann, Helga Midtbo, John B. Chambers, Eva Gerdts
Summary: The study found that in asymptomatic nonsevere aortic valve stenosis and low-gradient severe AS, a higher AT/ET ratio is associated with increased cardiovascular morbidity and mortality.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Editorial Material
Medicine, General & Internal
Mai Tone Lonnebakken
Article
Cardiac & Cardiovascular Systems
Ester Kringeland, Grethe S. Tell, Helga Midtbo, Jannicke Igland, Teresa R. Haugsgjerd, Eva Gerdts
Summary: This study found that stage 1 hypertension is a stronger risk factor for acute coronary syndromes (ACS) in women than in men.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Ute Seeland, Janos Nemcsik, Mai Tone Lonnebakken, Karolina Kublickiene, Helena Schluchter, Chloe Park, Giacomo Pucci, Ioana Mozos, Rosa-Maria Bruno
Summary: Sex and gender play important roles in cardiovascular system physiology, pathophysiology, and disease development, particularly in the progression of vascular ageing and its impact on cardiovascular, renal, and cerebrovascular diseases. Understanding sex differences in physiological ageing and disease-related changes in vascular ageing trajectories is crucial to avoid misdiagnosis and mistreatment. Gender roles also influence the effectiveness of cardiovascular preventive strategies and acceptance of diagnostic and therapeutic measures, with health behaviors and sociocultural norms contributing to premature arterial vascular ageing. The VascAgeNet Gender Expert Group aims to advance the incorporation of non-invasive vascular ageing measures in routine clinical practices by addressing sex and gender differences and seeking solutions.
HEART LUNG AND CIRCULATION
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Helga Midtbo, Eva Gerdts
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Rheumatology
C. L. Alsing, T. W. Nystad, J. Igland, C. G. Gjesdal, H. Midtbo, G. S. Tell, B. T. Fevang
Summary: Incidence rates and excess events of AMI and IHD in RA patients declined from 1972 to 2017. There were no excess AMI or IHD events in RA patients diagnosed after 1998 compared with the general population.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Edda Bahlmann, Eigir Einarsen, Dana Cramariuc, Eva R. Pedersen, Anne B. Rossebo, Helga Midtbo, Stephan Willems, Eva Gerdts
Summary: This study suggests that asymptomatic AS patients who have discordant grading after adjustment for pressure recovery are at increased cardiovascular risk, including heart failure and death.
Article
Peripheral Vascular Disease
Gyda Ullensvang, Ester Kringeland, Eirik Ikdahl, Sella Provan, Inger Jorid Berg, Silvia Rollefstad, Hanne Dagfinrud, Eva Gerdts, Anne Grete Semb, Helga Midtbo
Summary: This study investigated the prevalence of cardiovascular organ damage associated with hypertension in patients with ankylosing spondylitis (AS). The results showed that 34% of AS patients had hypertension, and 84% of AS patients with hypertension had cardiovascular organ damage. These findings highlight the importance of guideline-directed hypertension management in AS patients to reduce cardiovascular disease.
Article
Peripheral Vascular Disease
Annabel Eide Ohldieck, Ester Kringeland, Helga Midtbo, Grethe S. Tell, Eva Gerdts
Summary: This study aimed to identify modifiable risk factors in early midlife associated with incident hypertension 26 years later in women and men. The results showed that high-normal blood pressure in midlife was a significantly stronger risk factor for the development of hypertension in women than in men during follow-up, independent of body mass index.
Article
Medicine, General & Internal
Katrine Tryti Lindseth, Eva Gerdts, Helga Midtbo, Nadia Pristaj, Dana Cramariuc, Eigir Einarsen
Summary: This study investigated the relation between global myocardial work index (GWI) and sex and increased body mass index (BMI). The results showed that women had higher GWI, which was mainly explained by increased left ventricular (LV) workload due to higher aortic augmentation pressure in women.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
John G. Eikas, Eva Gerdts, Hilde Halland, Helga Midtbo, Dana Cramariuc, Ester Kringeland
Summary: This study explored sex differences in arterial stiffness among individuals with overweight and obesity. Women had higher augmentation pressure and augmentation index, while men had higher carotid-femoral pulse wave velocity. Age and 24-hour systolic blood pressure were the main factors associated with arterial stiffness in both sexes.
HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
(2023)
Review
Cardiac & Cardiovascular Systems
Enxhela Sulo, Einar Skulstad Davidsen, Mai Tone Lonnebakken, Oyvind Bleie, Sahrai Saeed
Summary: This study reported paradoxical sinus deceleration observed during dobutamine stress echocardiography in six patients and described its occurrence patterns and clinical characteristics. The deceleration mainly occurred at maximal dobutamine infusion, accompanied by a decrease in blood pressure and resolved spontaneously after cessation of dobutamine infusion. Patients experiencing paradoxical sinus deceleration commonly had abnormal left ventricle geometry but differed in terms of age, sex, and cardiometabolic risk factors.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Article
Immunology
Helga Midtbo, Ester Kringeland, Eva Gerdts, Per Magne Ueland, Klaus Meyer, Anja Linde, Arve Ulvik, Roland Jonsson, Kare Steinar Tveit
Summary: This study explored the association of inflammation with left ventricular remodelling in psoriasis patients receiving treatment with TNF-alpha blocker infliximab. The results showed that higher levels of inflammatory biomarkers were associated with greater LV mass index in psoriasis patients, indicating a role of chronic inflammation in LV remodelling.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
(2022)
Article
Peripheral Vascular Disease
Silje Kjellevold Storesund, Iman Karaji, Elin Strand, Asbjorn Svardal, Mai Tone Lonnebakken, Rolf Kristian Berge, Gard Frodahl Tveitevag Svingen, Ottar Kjell Nygard, Eva Ringdal Pedersen
Summary: This study explored the predictive role of carnitine metabolites in cardiovascular disease and all-cause mortality among patients with non-obstructive coronary artery disease. The results showed that serum levels of acetyl, octanoyl-, and palmitoylcarnitine were associated with CVD mortality. Higher levels of acetyl- and palmitoylcarnitine were also linked to increased risk of all-cause mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY CARDIOVASCULAR RISK AND PREVENTION
(2022)
Article
Multidisciplinary Sciences
Caroline A. Berge, Ingeborg Eskerud, Elise B. Almeland, Terje H. Larsen, Eva R. Pedersen, Svein Rotevatn, Mai Tone Lonnebakken
Summary: This study aimed to investigate the association between hypertension and extensive non-obstructive coronary artery disease (CAD) in patients with symptomatic chronic coronary syndrome (CCS). The results showed that hypertension was associated with extensive non-obstructive CAD in CCS patients, independent of factors such as sex, age, smoking, diabetes, statin treatment, obesity, and calcium score.
