Article
Mathematics, Applied
Miloslav Torda, Ohn Y. Goulermas, Roland Pucek, Vitaliy Kurlin
Summary: Molecular crystal structure prediction is achieved by searching for the most stable periodic structure using global optimization methods within a complex energy landscape induced by intermolecular potentials. In this study, we propose a search method for the densest periodic packings restricted to crystallographic symmetry groups, and evaluate its performance on various known optimal solutions in 2-dimensional CSGs and its application in pentacene thin-film CSP.
SIAM JOURNAL ON SCIENTIFIC COMPUTING
(2023)
Article
Physics, Multidisciplinary
Edward Bormashenko
Summary: The study explores the temperature-dependent entropic force between a matrix of magnets and direct current, finding that the entropic force acts as repulsion at a large distance and scales with temperature.
Article
Instruments & Instrumentation
Ch Rothleitner, I Poroskun, S. Svitlov, J. Kloss, J. Konrad
Summary: This paper presents a method for using high harmonics correction in a table-top version of a Kibble balance, allowing it to be used as a conventional balance in a short motion range.
Review
Chemistry, Multidisciplinary
Xiqi Zhang, Bo Song, Lei Jiang
Summary: The ordered and high-flux flow of molecules and ions in biological channels is considered a quantum-confined superfluid with attraction-repulsion balance of particles under the effect of interfacial confinement. The competition of attractive potential energy with disorder caused by thermal noise results in phase transition temperature, enabling the formation of superfluids at certain confined distances for molecules and ions.
Article
Multidisciplinary Sciences
A. Delafontaine, T. Vialleron, D. G. Diakhate, P. Fourcade, E. Yiou
Summary: This study investigated the effects of cervical spine mobility on postural control during gait initiation. The results showed that high restriction of cervical spine mobility altered anticipatory postural adjustments and motor performance, potentially reflecting a cautious strategy to attenuate head instability and enhance postural control. Clinicians should be aware that prescribing rigid neck orthosis to patients with postural deficits could worsen gait initiation deficits.
SCIENTIFIC REPORTS
(2022)
Article
Metallurgy & Metallurgical Engineering
Venkat Arunchaitanya Gadi, Govind Sharan Gupta
Summary: In many systems, liquid flows in discrete rivulet/droplet form in non-wetting or low liquid flow rate conditions. The discrete liquid flow (DLF) theory has been used to describe these systems, but it has not been verified for random packing or 2D structural packing without gas flow. This article validates the DLF theory for structural packing without gas flow and extends it to include random packing. The study confirms the importance of bed topology in dictating liquid flow behavior in a randomly packed bed.
ISIJ INTERNATIONAL
(2023)
Article
Physics, Multidisciplinary
Nico Konig, Lutz Willner, Vitaliy Pipich, Najet Mahmoudi, Reidar Lund
PHYSICAL REVIEW LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Ken Schaefer, Hima Bindu Kolli, Mikkel Killingmoe Christensen, Sigbjorn Loland Bore, Gregor Diezemann, Juergen Gauss, Giuseppe Milano, Reidar Lund, Michele Cascella
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Chemistry, Multidisciplinary
Sandra Rodriguez-Fabia, Marita Oyen, Nicolai Winter-Hjelm, Jens Norrman, Reidar Lund, Geir Humborstad Sorland, Hanna K. Knuutila, Johan Sjoblom, Kristofer Gunnar Paso
MOLECULAR CRYSTALS AND LIQUID CRYSTALS
(2020)
Article
Chemistry, Multidisciplinary
Synne Myhre, Matthias Amann, Lutz Willner, Kenneth D. Knudsen, Reidar Lund
Article
Multidisciplinary Sciences
Natalia Molchanova, Josefine Eilso Nielsen, Kristian B. Sorensen, Bala Krishna Prabhala, Paul Robert Hansen, Reidar Lund, Annelise E. Barron, Havard Jenssen
SCIENTIFIC REPORTS
(2020)
Article
Chemistry, Medicinal
Ho Yeon Nam, Jieun Choi, S. Dinesh Kumar, Josefine Eilso Nielsen, Minkyu Kyeong, Sungrok Wang, Dahyun Kang, Yunjee Lee, Jiyoun Lee, Myung-Han Yoon, Sukwon Hong, Reidar Lund, Havard Jenssen, Song Yub Shin, Jiwon Seo
ACS INFECTIOUS DISEASES
(2020)
Article
Chemistry, Physical
Josefine Eilso Nielsen, Victoria Ariel Bjornestad, Vitaliy Pipich, Havard Jenssen, Reidar Lund
Summary: By combining state-of-the-art small angle X-ray/neutron scattering techniques, this study found that various natural antimicrobial peptides accelerate essential lipid transport processes without altering the overall structure of lipid membranes, potentially triggering lethal signaling processes and enhancing ion transport.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Polymer Science
Nico Koenig, Lutz Willner, Goran Carlstrom, Thomas Zinn, Kenneth D. Knudsen, Frode Rise, Daniel Topgaard, Reidar Lund
Article
Chemistry, Multidisciplinary
Victoria Ariel Bjornestad, Marcella Orwick-Rydmark, Reidar Lund
Summary: Lipid nanodiscs formed by mixtures of styrene maleic acid (SMA) copolymers and lipid membranes are important tools for studying membrane proteins, with the formation pathways depending strongly on factors such as temperature, lipid/ copolymer ratio, and lipid type. The initial aggregation of copolymer in solution leads to insertion of its styrene units into the lipid bilayer hydrocarbon region, causing fractures in the membrane.
Article
Chemistry, Multidisciplinary
Josefine Eilso Nielsen, Reidar Lund
Summary: This study investigates the effect of adding the antimicrobial peptide indolicidin on lipid transport, vesicular growth, and lipid exchange rates in lipid vesicles. The results show that the peptide accelerates lipid transport and induces limited vesicular growth, with DMPG exhibiting faster kinetics. Vesicular growth is mainly associated with peptide-mediated lipid reorganization, which slightly affects overall exchange kinetics.
Article
Chemistry, Medicinal
Josefine Eilso Nielsen, Morgan Ashley Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A. Fortkort, Jennifer S. Lin, Gill Diamond, Robert E. W. Hancock, Havard Jenssen, Daniel Pletzer, Reidar Lund, Annelise E. Barron
Summary: Antimicrobial peptides (AMPs) show promise as pharmaceutical candidates for preventing and treating infections caused by multidrug-resistant pathogens. Peptoids, designed as AMP mimics, exhibit antibacterial activity through self-assembly, with different morphologies affecting efficacy.
ACS INFECTIOUS DISEASES
(2022)
Article
Chemistry, Physical
J. Royes, V. A. Bjornestad, G. Brun, T. Narayanan, R. Lund, C. Tribet
Summary: Photoswitchable surfactants are used in the design of light-responsive colloids and self-assemblies. This study investigates the intermediate lipid-surfactant assemblies formed during fast isothermal photo-triggered transitions. The experiments reveal that the transient assemblies detected during the photo-triggered kinetics are similar to the stationary states. Additionally, the reorganization speed of surfactant-enriched assemblies is faster than that of lipid-enriched ones.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Immunology
Daniel Hatlem, Mikkel Christensen, Nina K. Broeker, Per E. Kristiansen, Reidar Lund, Stefanie Barbirz, Dirk Linke
Summary: Alpha-helical coiled-coils are common protein structures found in all living organisms. Modified coiled-coil sequences have been widely used in biotechnology, vaccine development, and biochemical research to induce protein oligomerization and form self-assembled protein scaffolds. In this study, a trimeric variant of a peptide derived from the yeast transcription factor GCN4, called GCN4-pII, was shown to bind bacterial lipopolysaccharides (LPS) with high affinity. LPS molecules are toxic glycolipids found in the outer membrane of Gram-negative bacteria. The researchers also demonstrated the ability of GCN4-pII to break down LPS micelles in solution. These findings suggest that GCN4-pII and its derivatives could be used for novel LPS detection and removal solutions with important applications in the production and quality control of biopharmaceuticals and other biomedical products, where even trace amounts of residual LPS can be deadly.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Chemistry, Physical
Victoria Ariel Bjornestad, Fernando Soto-Bustamante, Giancarlo Tria, Marco Laurati, Reidar Lund
Summary: This study investigates the structural pathways and metastable structures involved in the solubilization of lipid membranes using the non-ionic detergent Triton X-100. The findings reveal a unique ripple phase of ordered rippled bilamellar disc structures formed when moderate amounts of detergent are added to lipid vesicles, suggesting a combination of water structure destabilization and osmotic pressure causing interbilayer attraction. The study highlights the diversity in assembly pathways of simple lipids and detergents and their implications for membrane solubilization.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Josefine Eilso Nielsen, Sylvain Francois Prevost, Havard Jenssen, Reidar Lund
Summary: This study combines SAXS/SANS techniques to investigate the effect of antimicrobial peptides on the cytoplasmic membrane of Escherichia coli. Various AMPs were found to significantly impact the dynamics of phospholipids in the membrane.
FARADAY DISCUSSIONS
(2021)