Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials
出版年份 2019 全文链接
标题
Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials
作者
关键词
-
出版物
MOLECULES
Volume 24, Issue 8, Pages 1459
出版商
MDPI AG
发表日期
2019-04-15
DOI
10.3390/molecules24081459
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Metabolomic analyses of vigabatrin (VGB)-treated mice: GABA-transaminase inhibition significantly alters amino acid profiles in murine neural and non-neural tissues
- (2019) Dana C. Walters et al. NEUROCHEMISTRY INTERNATIONAL
- Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results
- (2018) Jerzy P. Szaflarski et al. EPILEPSIA
- Efficacy of artisanal preparations of cannabidiol for the treatment of epilepsy: Practical experiences in a tertiary medical center
- (2018) Giulia S. Porcari et al. EPILEPSY & BEHAVIOR
- Open-label use of Highly* purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes
- (2018) Orrin Devinsky et al. EPILEPSY & BEHAVIOR
- Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial
- (2018) Elizabeth A Thiele et al. LANCET
- Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome
- (2018) Orrin Devinsky et al. NEUROLOGY
- Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome
- (2018) Orrin Devinsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study
- (2018) Jerzy P. Szaflarski et al. EPILEPSY & BEHAVIOR
- Cannabidiol for treating drug-resistant epilepsy in children: the New South Wales experience
- (2018) Kerrie-Anne Chen et al. MEDICAL JOURNAL OF AUSTRALIA
- Long-Term Safety, Tolerability, and Efficacy of Cannabidiol in Children with Refractory Epilepsy: Results from an Expanded Access Program in the US
- (2018) Tristan T. Sands et al. CNS DRUGS
- Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial
- (2018) Orrin Devinsky et al. EPILEPSIA
- Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series
- (2018) Lucas Elms et al. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
- Seizures and Epilepsy
- (2018) Emily L. Johnson MEDICAL CLINICS OF NORTH AMERICA
- Interactions between cannabidiol and commonly used antiepileptic drugs
- (2017) Tyler E. Gaston et al. EPILEPSIA
- Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol
- (2017) Evan C. Rosenberg et al. EPILEPSIA
- Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology
- (2017) Robert S. Fisher et al. EPILEPSIA
- Anticonvulsant effect of cannabidiol in the pentylenetetrazole model: Pharmacological mechanisms, electroencephalographic profile, and brain cytokine levels
- (2017) Luciano R. Vilela et al. EPILEPSY & BEHAVIOR
- Cannabinoids in treatment-resistant epilepsy: A review
- (2017) Brooke K. O'Connell et al. EPILEPSY & BEHAVIOR
- Mechanisms of action of cannabidiol in adoptively transferred experimental autoimmune encephalomyelitis
- (2017) Coral González-García et al. EXPERIMENTAL NEUROLOGY
- Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy
- (2017) William A. Catterall NEUROCHEMICAL RESEARCH
- Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome
- (2017) Orrin Devinsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome
- (2017) Emma H. Kaplan et al. PEDIATRIC NEUROLOGY
- Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome
- (2017) Joshua S. Kaplan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease
- (2017) Georgia Watt et al. Frontiers in Pharmacology
- Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex
- (2016) Evan J. Hess et al. EPILEPSIA
- Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages
- (2016) Thangavelu Soundara Rajan et al. FITOTERAPIA
- Gingival Stromal Cells as an In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis
- (2016) Thangavelu Soundara Rajan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
- (2016) Orrin Devinsky et al. LANCET NEUROLOGY
- Protective effect of cannabidiol on hydrogen peroxide-induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells
- (2016) Jie Chen et al. Molecular Medicine Reports
- Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
- (2016) Raquel Linge et al. NEUROPHARMACOLOGY
- Cannabidiol (CBD) and its analogs: a review of their effects on inflammation
- (2015) Sumner Burstein BIOORGANIC & MEDICINAL CHEMISTRY
- TRPV1 Channel: A Potential Drug Target for Treating Epilepsy
- (2015) Mustafa Nazıroglu Current Neuropharmacology
- Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy
- (2015) Alexandra L. Geffrey et al. EPILEPSIA
- Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox–Gastaut syndrome
- (2015) Shaun A. Hussain et al. EPILEPSY & BEHAVIOR
- Effects of Levetiracetam, Carbamazepine, Phenytoin, Valproate, Lamotrigine, Oxcarbazepine, Topiramate, Vinpocetine and Sertraline on Presynaptic Hippocampal Na+ and Ca2+ Channels Permeability
- (2015) María Sitges et al. NEUROCHEMICAL RESEARCH
- Molecular Targets of Cannabidiol in Neurological Disorders
- (2015) Clementino Ibeas Bih et al. Neurotherapeutics
- The neuroprotection of cannabidiol against MPP + -induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease
- (2015) Neife Aparecida Guinaim Santos et al. TOXICOLOGY IN VITRO
- Seizures and Epilepsy: An Overview for Neuroscientists
- (2015) C. E. Stafstrom et al. Cold Spring Harbor Perspectives in Medicine
- Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?
- (2015) Bruno P. Guiard et al. Frontiers in Pharmacology
- Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
- (2014) Attila Oláh et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial
- (2014) Marcos Hortes N Chagas et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Understanding the Molecular Aspects of Tetrahydrocannabinol and Cannabidiol as Antioxidants
- (2013) Rosivaldo Borges et al. MOLECULES
- Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
- (2013) M. Mecha et al. NEUROBIOLOGY OF DISEASE
- Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
- (2013) Matthew D. Shirley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Valproic acid pathway
- (2013) Yogita Ghodke-Puranik et al. Pharmacogenetics and Genomics
- Delta opioid receptors in brain function and diseases
- (2013) Paul Chu Sin Chung et al. PHARMACOLOGY & THERAPEUTICS
- The role of different serotonin receptor subtypes in seizure susceptibility
- (2013) Mohammad Hadi Gharedaghi et al. EXPERIMENTAL BRAIN RESEARCH
- Cannabidiol as potential anticancer drug
- (2012) Paola Massi et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Neuroprotective agents: Cannabinoids
- (2011) A.J. Sánchez et al. CLINICAL IMMUNOLOGY
- Serotonin 1A receptors, depression, and memory in temporal lobe epilepsy
- (2011) William H. Theodore et al. EPILEPSIA
- Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: Role of phenolic hydroxyl groups in the resorcinol moiety
- (2011) Satoshi Yamaori et al. LIFE SCIENCES
- Presentation, Diagnosis, Pathophysiology, and Treatment of the Neurological Features of Sturge-Weber Syndrome
- (2011) Anne M. Comi NEUROLOGIST
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour
- (2011) Serena Deiana et al. PSYCHOPHARMACOLOGY
- Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
- (2010) Sabatino Maione et al. BRITISH JOURNAL OF PHARMACOLOGY
- Infantile spasms: A U.S. consensus report
- (2010) John M. Pellock et al. EPILEPSIA
- Interaction between cytokines, cannabinoids and the nervous system
- (2010) Lucie Jean-Gilles et al. IMMUNOBIOLOGY
- Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
- (2009) Patrick Kwan et al. EPILEPSIA
- Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo
- (2009) N. A. Jones et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors
- (2009) A. Castillo et al. NEUROBIOLOGY OF DISEASE
- Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology
- (2009) Sagnik Bhattacharyya et al. NEUROPSYCHOPHARMACOLOGY
- The anti-convulsant stiripentol acts directly on the GABAA receptor as a positive allosteric modulator
- (2008) Janet L. Fisher NEUROPHARMACOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started