Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

The efficacy and safety of targeted therapy with or without chemotherapy in advanced gastric cancer treatment: a network meta-analysis of well-designed randomized controlled trials

(2018) Ting-Ting Zhao et al.   Gastric Cancer

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

(2018) Yinghua Zhu et al.   Nature Communications

Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression

(2017) Dan Han et al.   HEPATOLOGY

Human Helicase RECQL4 Drives Cisplatin Resistance in Gastric Cancer by Activating an AKT-YB1-MDR1 Signaling Pathway

(2016) D. Mo et al.   CANCER RESEARCH

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

(2016) Kun Wang et al.   EUROPEAN HEART JOURNAL

Circular RNAs are miRNA sponges and can be used as a new class of biomarker

(2016) Franceli Rodrigues Kulcheski et al.   JOURNAL OF BIOTECHNOLOGY

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

(2016) Aditya Bagrodia et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting therapeutic liabilities engendered by PIK3R1 mutations for cancer treatment

(2016) Lydia WT Cheung et al.   PHARMACOGENOMICS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

MIR517Cinhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation

(2015) Yuntao Lu et al.   Autophagy

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Update on Metastatic Gastric and Esophageal Cancers

(2015) Manish A. Shah   JOURNAL OF CLINICAL ONCOLOGY

Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

(2015) Kristen M. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1–miR-593-5p–MFF axis

(2015) Song Fan et al.   Oncotarget

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer

(2015) Da Li et al.   Oncotarget

BRCA1 as a nicotinamide adenine dinucleotide (NAD)-dependent metabolic switch in ovarian cancer

(2014) Da Li et al.   CELL CYCLE

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation

(2014) Da Li et al.   Molecular Cancer

BRCA1-IRIS inactivation sensitizes ovarian tumors to cisplatin

(2014) B T Paul et al.   ONCOGENE

Systems biology of cisplatin resistance: past, present and future

(2014) L Galluzzi et al.   Cell Death & Disease

SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non-Small Cell Lung Cancers to Cisplatin and Doxorubicin

(2013) D. H. Shin et al.   CANCER RESEARCH

miR-9 Regulation of BRCA1 and Ovarian Cancer Sensitivity to Cisplatin and PARP Inhibition

(2013) Chaoyang Sun et al.   JNCI-Journal of the National Cancer Institute

BRCA1-Dependent Translational Regulation in Breast Cancer Cells

(2013) Estelle Dacheux et al.   PLoS One

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel

(2008) Lifeng Wang et al.   BMC CANCER

Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt

(2008) X Yang et al.   BRITISH JOURNAL OF CANCER

S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial

(2008) Wasaburo Koizumi et al.   LANCET ONCOLOGY

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

(2008) R. C-Y. Hui et al.   MOLECULAR CANCER THERAPEUTICS

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH