Review
Oncology
Erin Pitt, Natalie Bradford, Eden Robertson, Ursula M. Sansom-Daly, Kimberly Alexander
Summary: The study aimed to identify and synthesize the available literature regarding the effects of Decision Support Systems (DSS) on patient-reported outcomes during and after cancer treatment. The findings showed mixed results, with DSS interventions being effective in reducing pain but not significantly improving other health-related patient-reported outcomes.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2023)
Review
Oncology
Madeline R. Horan, Jin-ah Sim, Kevin R. Krull, Kirsten K. Ness, Yutaka Yasui, Leslie L. Robison, Melissa M. Hudson, Justin N. Baker, I-Chan Huang
Summary: Patient-reported outcome measures (PROMs) are useful in assessing the subjective experiences of childhood cancer survivors and can be used to monitor health status and inform medical decision making. This article provides 10 important considerations for clinicians when assessing PROMs for childhood cancer survivors, addressing practical barriers and solutions. An example framework for integrating PROMs into clinical workflow using cutting-edge technologies is also discussed.
Article
Otorhinolaryngology
Maarten C. Dorr, Aniel Sewnaik, Diako Berzenji, Kira S. van Hof, Tim Grevelink, Robert J. Baatenburg de Jong, Marinella P. J. Offerman
Summary: This study aims to use structurally obtained patient-reported outcome data combined with clinical patient data to improve end-of-life care and patient-centered counseling for patients with palliative head and neck cancer. The study found a significant deterioration in various aspects of quality of life, but also an improvement in emotional functioning over time. The results highlight the importance of incorporating both patient-reported outcomes and clinical outcomes in improving patient-centered care.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Dermatology
Aaron M. Secrest, Mary-Margaret Chren
Summary: Patient-reported outcomes (PROs) provide comprehensive and informative assessments of patients' experiences with skin diseases, which may not necessarily correlate with clinician assessments. PROs should serve as vital signs for skin in dermatology.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
Review
Computer Science, Information Systems
Anindya Pradipta Susanto, David Lyell, Bambang Widyantoro, Shlomo Berkovsky, Farah Magrabi
Summary: This study aims to summarize the research literature evaluating machine learning (ML)-based clinical decision support (CDS) systems in healthcare settings. The findings suggest that ML-based CDS systems have been applied successfully in assisting clinical tasks, but their effects on decision-making, care delivery, and patient outcomes are mixed.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Editorial Material
Oncology
Cristiane Decat Bergerot, Sumanta K. Pal, Abhishek Tripathi
Summary: This commentary discusses the potential relevance and barriers to including patient-reported outcomes in early phase trials.
Review
Health Care Sciences & Services
Ramkumar Govindaraj, Meera Agar, David Currow, Tim Luckett
Summary: This study explored the mechanisms underlying ePROM interventions in cancer clinical care and developed program theories on how and when these interventions improve health outcomes. The findings suggest that remote symptom self-reporting, real-time clinician feedback, and clinician-patient interactions are key components of effective ePROM interventions. However, the intended benefits may not be achieved if ePROMs are not meaningful to patients or increase clinicians' workload.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Editorial Material
Biochemistry & Molecular Biology
Ameeta Retzer, Olalekan Lee Aiyegbusi, Anna Rowe, Philip N. Newsome, Jessica Douglas-Pugh, Sheeba Khan, Saloni Mittal, Roger Wilson, Daniel O'Connor, Lisa Campbell, Sandra A. Mitchell, Melanie Calvert
Summary: Patient-reported outcomes can offer preliminary evidence of efficacy and tolerability from the patient's perspective, and they can also support regulatory review.
Article
Oncology
Anna E. E. Coghill, Naomi C. C. Brownstein, Sweta Sinha, Zachary J. J. Thompson, Brittney L. L. Dickey, Aasha I. I. Hoogland, Peter A. A. Johnstone, Gita Suneja, Heather S. S. Jim
Summary: Cancer patients with HIV are more likely to experience severe symptoms during their cancer care, including severe pain and depression, which are also linked to higher mortality rates.
Review
Oncology
Jens Lehmann, Maria Rothmund, David Riedl, Gerhard Rumpold, Vincent Grote, Michael J. Fischer, Bernhard Holzner
Summary: The goal of cancer rehabilitation is to help patients recover physically and psychologically after acute cancer treatment and regain their social life. To assess the effectiveness of rehabilitation interventions, it is important to measure their outcomes. This can be done through clinician reports, patient performance testing, observation of behavior, or direct patient feedback. This paper focuses on patient reports and provides an overview of available questionnaires for assessment and advice on their use. The use of electronic systems for collecting data is highlighted as the most promising approach. The assessment of patient perspective aims to inform decisions on choosing and reimbursing rehabilitation interventions based on patients' needs. The article reviews different types of clinical outcome assessments and emphasizes the importance of patient-reported outcomes (PROs) which provide direct reports from patients about their health condition without interpretation by a third party. The article also discusses the current state of PRO implementation in cancer rehabilitation, highlights trends in using PROs for value-based care, and provides examples of PRO usage and the benefits of electronic PRO collection. Advice is offered on selecting, implementing, and integrating PROs into cancer rehabilitation settings to maximize efficiency.
Article
Oncology
C. Mazariego, M. Jefford, R. J. Chan, N. Roberts, L. Millar, A. Anazodo, S. Hayes, B. Brown, C. Saunders, K. Webber, J. Vardy, A. Girgis, B. Koczwara
Summary: The aim of this study was to develop priority recommendations for the service level implementation of patient-reported outcomes (PROs) into clinical cancer care. A two-round modified Delphi survey was conducted to rank and prioritize statements related to PRO implementation. The results highlighted the importance of clinical relevance, stakeholder engagement, communication, and integration within existing processes and capabilities in implementing PROs in clinical cancer care.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Article
Pediatrics
Isabel I. Sreeram, Chantal A. ten Kate, Joost van Rosmalen, Johannes M. Schnater, Saskia J. Gischler, Rene M. H. Wijnen, Hanneke IJsselstijn, Andre B. Rietman
Summary: The study examined the added value of self-reported PROMs for the health status and quality of life of children with foregut anomalies, finding a significant association between lower cognition and lower self-reported health status in children with CDH and EA, while analysis in children with CLM was limited due to a low number of cases. Health status, quality of life, and clinical outcomes represent different aspects of a child's wellbeing, emphasizing the importance of measuring them simultaneously for a holistic approach to clinical decision making.
Review
Oncology
David Riedl, Maria Rothmund, Anne-Sophie Darlington, Samantha Sodergren, Roman Crazzolara, Teresa de Rojas
Summary: This study found that the use of patient-reported outcomes (PROs) is extremely rare in pediatric oncology clinical trials, with only 8.2% of trials using PROs as endpoints and .6% as the primary endpoint. Despite recommendations from regulatory agencies, there is a significant gap between the recommended and actual use of PROs, with only 20.3% of closed studies publishing their results. More efforts should be made to promote the implementation of PROs in pediatric trials to ensure patient-centered research and treatments.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Health Care Sciences & Services
Anne Louise Depla, Marije Lamain-de Ruiter, Lyzette Laureij, Hiske E. Ernst-Smelt, Jan A. Hazelzet, Arie Franx, Mireille N. Bekker, BUZZ Project Team
Summary: This study reports the initial outcomes, experiences, and practice insights of implementing the PCB set in clinical practice in the Netherlands. The results indicate that the PCB set is a useful tool to assess patient-reported outcomes and experiences that need to be addressed throughout pregnancy and childbirth, providing opportunities to improve and personalize perinatal care.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Multidisciplinary Sciences
Wang-Chuan Juang, Ming-Hsia Hsu, Zheng-Xun Cai, Chia-Mei Chen
Summary: Holistic health care is essential for complete patient care, and an efficient clinical decision support system (CDSS) is crucial to support physicians' judgement. This study proposes an AI-assisted CDSS model using an improved recurrent neural network (RNN) to predict patients in need of holistic health care.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sharon W. Kwan, Resmi A. Charalel, Angela M. Stover, Judith F. Baumhauer, David Cella, Gwen Darien, Jeremy C. Durack, Jason Gerson, Frank Opelka, Donald L. Patrick, Riad Salem, James B. Spies, Albert W. Wu, Sarah B. White
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Article
Oncology
Sarah A. Birken, Robin Urquhart, Corrine Munoz-Plaza, Alexandra R. Zizzi, Emily Haines, Angela Stover, Deborah K. Mayer, Erin E. Hahn
JOURNAL OF CANCER SURVIVORSHIP
(2018)
Editorial Material
Oncology
Bogda Koczwara, Angela M. Stover, Louise Davies, Melinda M. Davis, Linda Fleisher, Shoba Ramanadhan, Florian R. Schroeck, Leah L. Zullig, David A. Chambers, Enola Proctor
JOURNAL OF ONCOLOGY PRACTICE
(2018)
Article
Oncology
Ashley Leak Bryant, Erin M. Coffman, Elizabeth Bullard, Rachel Hirschey, Joshua Bradley, Angela Stover, William A. Wood, Antonia V. Bennett
JOURNAL OF ONCOLOGY PRACTICE
(2018)
Article
Health Care Sciences & Services
Kea Turner, Justin G. Trogdon, Morris Weinberger, Angela M. Stover, Stefanie Ferreri, Joel F. Farley, Neepa Ray, Michael Patti, Chelsea Renfro, Christopher M. Shea
IMPLEMENTATION SCIENCE
(2018)
Article
Oncology
Ashley Leak Bryant, Erin Coffman, Brett Phillips, Xianming Tan, Elizabeth Bullard, Rachel Hirschey, Joshua Bradley, Antonia V. Bennett, Angela M. Stover, Lixin Song, Thomas C. Shea, William A. Wood
SUPPORTIVE CARE IN CANCER
(2020)
Article
Health Care Sciences & Services
Angela M. Stover, Lotte Haverman, Hedy A. van Oers, Joanne Greenhalgh, Caroline M. Potter
Summary: Across case studies, consistent barriers to PROM/PREM implementation were identified, including technology issues, uncertainty about how or why to use PROMs/PREMs, and competing demands from established clinical workflows. However, enabling factors were context specific in each clinic, highlighting the need for tailored implementation strategies based on clinic resources. Further theoretically guided studies are needed to explore how IS principles can lead to successful integration and sustainability of PROM/PREMs.
QUALITY OF LIFE RESEARCH
(2021)
Letter
Health Care Sciences & Services
Angela M. Stover, Liv Marit Valen Schougaard, Kate Absolom
QUALITY OF LIFE RESEARCH
(2020)
Review
Oncology
Angela M. Stover, Rachel Kurtzman, Jennifer Walker Bissram, Jennifer Jansen, Philip Carr, Thomas Atkinson, C. Tyler Ellis, Ashley T. Freeman, Kea Turner, Ethan M. Basch
Summary: Through a systematic review, stakeholders in oncology prioritize psychosocial care and symptom management as key components of high-quality care. Patients, caregivers, clinicians, and healthcare administrators also recognize the importance of maintaining physical function and daily activities, with specific symptoms like pain, poor sleep, and gastrointestinal issues being seen as critical by clinicians and administrators. This information was used to inform testing and evaluation of care provided by six cancer centers.
Article
Urology & Nephrology
Angela M. Stover, Ramsankar Basak, Dana Mueller, Robert Lipman, Randall Teal, Alison Hilton, Kara Giannone, Myra Waheed, Angela B. Smith
Summary: Optima II is a clinical trial evaluating a nonsurgical alternative as a primary treatment for nonmuscle-invasive bladder cancer. The study found that using UGN-102 as a primary treatment did not cause significant side effects and was well-received by patients.
JOURNAL OF UROLOGY
(2022)
Article
Multidisciplinary Sciences
Angela M. Stover, Mian Wang, Christopher M. Shea, Erica Richman, Jennifer Rees, Andrea L. Cherrington, Doyle M. Cummings, Liza Nicholson, Shannon Peaden, Macie Craft, Monique Mackey, Monika M. Safford, Jacqueline R. Halladay
Summary: This study examined the construct validity, reliability, and longitudinal trend of the Key Driver Implementation Scale (KDIS) in primary care practices. The results showed that KDIS had acceptable reliability, but further research is needed in larger sample sizes to determine if multiple groups of implementation activities are being measured rather than one.
Article
Oncology
Kea Turner, Angela M. Stover, Danielle B. Tometich, Carley Geiss, Arianna Mason, Oliver T. Nguyen, Emma Hume, Rachael McCormick, Sean Powell, Julie Hallanger-Johnson, Krupal B. Patel, Kedar S. Kirtane, Neelima Jammigumpula, Colin Moore, Randa Perkins, Dana E. Rollison, Heather S. L. Jim, Laura B. Oswald, Sylvia Crowder, Brian D. Gonzalez, Edmondo Robinson, Amir Alishahi Tabriz, Jessica Y. Islam, Scott M. Gilbert
Summary: This study assessed the perspectives of oncology providers and professionals on the barriers and facilitators of implementing suicide risk screening for patients with head and neck cancer. Multilevel implementation barriers were identified, such as patient difficulty with using a tablet, limited nursing engagement, limited clinic Wi-Fi connectivity, and low clinician self-efficacy for interpreting and acting upon patient-reported outcome scores. Participants recommended strengthening patient and clinician education and providing alternative data entry modalities for patients.
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Ethan Basch, Angela M. Stover, Deborah Schrag, Arlene Chung, Jennifer Jansen, Sydney Henson, Philip Carr, Brenda Ginos, Allison Deal, Patricia A. Spears, Mattias Jonsson, Antonia V. Bennett, Gita Mody, Gita Thanarajasingam, Lauren J. Rogak, Bryce B. Reeve, Claire Snyder, Lisa A. Kottschade, Marjory Charlot, Anna Weiss, Deborah Bruner, Amylou C. Dueck
JCO CLINICAL CANCER INFORMATICS
(2020)
Article
Health Care Sciences & Services
Angela M. Stover, Lori D. McLeod, Michelle M. Langer, Wen-Hung Chen, Bryce B. Reeve
JOURNAL OF PATIENT-REPORTED OUTCOMES
(2019)