Article
Biochemistry & Molecular Biology
Jiantao Chen, Yingkang Dai, Xiangjun Gong, Guangzhao Zhang
Summary: The study reveals that Gdm(+) prefers to bind to thiol or hydroxyl groups, while NH4+ tends to bind to the alpha-carboxyl group. Hydrogen bonding is observed between NH4+ and the alpha-carboxyl group, which is not involved in the interactions between Gdm(+) and cysteine.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Songtai Gao, Yujun Sun, Zhong Lu, Nan Jiang, Huaiying Yao
Summary: Antibiotics overuse and misuse contribute to the emergence of multidrug-resistant bacterial strains and biofilm formation. This study screened out a combination of quaternary ammonium compound PDDA and Cu2+ as a promising antibacterial agent against Staphylococcus aureus. The combination showed strong synergistic antibacterial activity by disrupting membrane function, generating intracellular reactive oxygen, promoting Cu2+ uptake, and reducing biofilm extracellular matrix. In vitro biocompatibility studies demonstrated low cytotoxicity and hemolysis ratio. This work provides a novel and efficient strategy to combat planktonic and biofilm S. aureus infections.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Xingqin Fu, Yuejun Zhang, Xu Jia, Yongji Wang, Tingting Chen
Summary: This paper introduces the properties, synthesis methods, and application fields of quaternary ammonium salt polymers, summarizes the research progress in polymer synthesis, and analyzes the relationship between polymer structure and properties. The paper also provides suggestions for developing high molecular weight quaternary ammonium salt polymers.
Article
Nutrition & Dietetics
Kate M. Bermingham, Mohsen Mazidi, Paul W. Franks, Tyler Maher, Ana M. Valdes, Inbar Linenberg, Jonathan Wolf, George Hadjigeorgiou, Tim D. Spector, Cristina Menni, Jose M. Ordovas, Sarah E. Berry, Wendy L. Hall
Summary: This study characterized the variability and correlations of postprandial metabolite changes in a large cohort. The majority of metabolites showed significant changes after a meal, particularly in very large lipoprotein particles and ketone bodies. Strong correlations were observed between fasting and postprandial metabolites, although some metabolites showed weak correlations.
Article
Dentistry, Oral Surgery & Medicine
Michal Dekel-Steinkeller, Ervin I. Weiss, Trudi Lev-Dor Samovici, Itzhak Abramovitz
Summary: This study tests the antibacterial properties of a novel composite material containing quaternary ammonium silica particles (QASi). The results demonstrate that QASi effectively kills E. faecalis bacteria and has comparable antibacterial activity to previously described quaternary ammonium polyethyleneimine particles.
JOURNAL OF DENTISTRY
(2022)
Article
Chemistry, Physical
He Sun, Blake A. Hammann, Alexander B. Brady, Gurpreet Singh, Lisa M. Housel, Esther S. Takeuchi, Kenneth J. Takeuchi, Amy C. Marschilok, Sophia E. Hayes, Lisa F. Szczepura
Summary: The combination of powder XRD, solid-state NMR, and electrochemical impedance spectroscopy was used to study the high capacity primary lithium battery cathode material (Ag2VO2PO4) and its electrochemically reduced counterparts. The findings show that as reduction proceeds, the material transitions from crystalline to increasingly paramagnetic and amorphous. Further investigation using static and magic-angle spinning solid-state (51)V NMR spectroscopy provided insight into the structure changes of the reduced materials, indicating that the V-51 NMR tensor parameters are better indicators of local environment changes than the isotropic chemical shift.
CHEMISTRY OF MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Mitsuharu Tabuchi, Riki Kataoka, Koji Yazawa
Summary: The study found that samples of LiNi1/2Mn1/2O2 prepared by coprecipitation-calcination exhibited a biphasic structure below 950 degrees Celsius, with the minor Li-rich phase decreasing as the calcination temperature increased; while the single-phase LiNi1/2Mn1/2O2 sample obtained at 1000 degrees Celsius showed superior electrochemical performance. By setting an excess amount of Li2CO3 and calcining in air, Li-excess Li1+x(NiyMn1-y)(1-x)O-2 samples were synthesized and found to be useful as high-capacity positive electrode materials.
MATERIALS RESEARCH BULLETIN
(2021)
Article
Chemistry, Physical
Kumiko Yoshihara, Noriyuki Nagaoka, Aya Umeno, Akinari Sonoda, Hideki Obika, Yasuhiro Yoshida, Bart Van Meerbeek, Yoji Makita
Summary: Novel amino acid-silver complexes loaded with montmorillonite demonstrated high antibacterial efficacy, particularly inhibiting the growth of Streptococcus mutans in dental acrylic resin. The structure of the complexes influenced the presence of silver ions in chloride and their antibacterial efficacy. His-Ag-Mont could serve as an effective antibacterial agent for dental materials.
Article
Chemistry, Analytical
Klaudia W. Milc, Thomas Oerther, Joshua A. Dijksman, John P. M. van Duynhoven, Camilla Terenzi
Summary: A pressure-driven high-field MRI velocimetry platform was developed to accurately predict cooperative flow in strongly confined flow. Experimental observations showed that the cooperative flow of Carbopol in a 100 μm capillary was independent of flow conditions, while the cooperative flow of heterogeneous fat crystal dispersion (FCD) increased with gap size and applied pressure.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Brijith Thomas, Daniel Jardon-Alvarez, Raanan Carmieli, Johan van Tol, Michal Leskes
Summary: In DNP-NMR experiments, the polarization of unpaired electrons is transferred to nuclei, increasing the sensitivity of NMR signal. While this method is efficient in crystalline inorganic oxides, it is less effective in oxide glasses. The difference in efficiency can be attributed to shorter relaxation times and dielectric properties in glasses. These findings provide guidance in identifying suitable materials for the DNP approach.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Geosciences, Multidisciplinary
D. Grombacher, L. Liu, M. P. Griffiths, M. O. Vang, J. J. Larsen
Summary: Groundwater, a critical freshwater source for billions, is increasingly stressed by climate change, pollution, and overexploitation. Surface nuclear magnetic resonance (NMR), with recent advancements, shows great promise in locating and monitoring groundwater sources efficiently and accurately, even in previously inaccessible areas. The new technique, enabled by breakthroughs in transmitter capabilities and numerical modeling, delivers significant signal enhancements for high-fidelity groundwater measurements.
GEOPHYSICAL RESEARCH LETTERS
(2021)
Article
Physics, Applied
Moriyoshi Haruyama, Yuki Okigawa, Mitsuhiro Okada, Hideaki Nakajima, Toshiya Okazaki, Hiromitsu Kato, Toshiharu Makino, Takatoshi Yamada
Summary: We investigated the charge-state stabilization of shallow nitrogen-vacancy (NV) centers in (111) diamond using graphene/diamond junctions. Fluorescence stability and charge-state stability were measured on NV centers in both the graphene and graphene-free regions. The results showed that about half of the NV centers in the graphene-free region were unstable, while over 90% of the measured NV centers in the graphene region were stabilized as NV- centers. Graphene/diamond junctions significantly contribute to the charge-state stabilization of shallow NV- centers in (111) diamond.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Organic
Trinadh Kaicharla, Bhavani Shankar Chinta, Thomas R. Hoye
Summary: This article provides examples that demonstrate the value of using properly designed and easily performed doping experiments to gain insights about the nature of analytes in a H-1 NMR sample. By conducting doping experiments on a complex mixture and a simple mixture, multiple compounds were successfully identified, highlighting the advantage of doping experiments over comparing spectra from separate samples containing the same analyte.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Ming-Ming Zhu, Yu Fang, Yan-Chen Chen, Yu-Qing Lei, Li-Feng Fang, Bao-Ku Zhu, Hideto Matsuyama
Summary: A dual-functional ultrafiltration membrane containing quaternary ammonium and zwitterionic polymers was designed to overcome organic/bio-fouling, with improved hydrophilicity and antibacterial properties. The membrane showed higher flux recovery, lower protein adhesion, and efficient broad-spectrum antibacterial performance against S. aureus and E. coli. It effectively inhibited bacterial adhesion for long-term antibacterial properties, demonstrating potential for microbiologically contaminated water filtration processes.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Seong-Joo Lee, Kwon Kyu Yu, Seong-min Hwang, Sangwon Oh, Nam Woong Song, Hak-Sung Jung, Oc Hee Han, Jeong Hyun Shim
Summary: Low-field nuclear magnetic resonance spectroscopy provides limited spectral information, but the use of isotopically labeled molecules can overcome this limitation. This study investigates the correlation spectroscopy of 1-C-13-ethanol at low-field, demonstrating that even with a moderate spectral line width, a low-field 2D spectrum can reveal the coupling networks of isotopically labeled molecules.
Article
Chemistry, Multidisciplinary
Chih-Wei Tsai, Kuo-Hui Wu, Je-Chuang Wang, Chien-Chou Shih
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2017)
Article
Materials Science, Biomaterials
Wei-Che Hung, Kuo-Hui Wu, Dong-Yi Lyu, Ken-Fa Cheng, Wen-Chien Huang
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2017)
Article
Materials Science, Multidisciplinary
Kuo-Hui Wu, Wen-Chien Huang, Shu-Chen Chang, Ching-Hua Kao, Rong-Hwa Shyu
MATERIALS CHEMISTRY AND PHYSICS
(2019)
Article
Chemistry, Multidisciplinary
Je-Chuang Wang, Wen-Chien Huang, Ken-Fa Cheng, Nien-Tung Liu, Kuo-Hui Wu
Summary: The study evaluated the efficacy of expired disinfectants in deactivating biological and chemical toxins on building material surfaces. The results showed that despite being past their expiration dates, the disinfectants had high effectiveness in deactivating biological toxins.
Article
Chemistry, Multidisciplinary
Kuo-Hui Wu, Wen-Chien Huang, Shu-Chen Chang, Rong-Hwa Shyu
Summary: A colloidal silver nanoparticle-based lateral flow immunoassay was developed for the rapid detection of PEO pesticide residue in vegetables. The assay showed a high sensitivity and specificity, with no cross-reactivity to other pesticides.
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
