A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

(2018) Derek M Mason et al.   NUCLEIC ACIDS RESEARCH

A platform for functional assessment of large variant libraries in mammalian cells

(2017) Kenneth A. Matreyek et al.   NUCLEIC ACIDS RESEARCH

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

(2017) Danielle M. DiCara et al.   Scientific Reports

Transpo-mAb display: Transposition-mediated B cell display and functional screening of full-length IgG antibody libraries

(2016) Lorenz Waldmeier et al.   mAbs

Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

(2016) Mark Pogson et al.   Nature Communications

Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids

(2015) Tetsushi Sakuma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stable Enhanced Green Fluorescent Protein Expression After Differentiation and Transplantation of Reporter Human Induced Pluripotent Stem Cells Generated by AAVS1 Transcription Activator-Like Effector Nucleases

(2014) Yongquan Luo et al.   Stem Cells Translational Medicine

Exploiting CRISPR/Cas systems for biotechnology

(2013) Timothy R. Sampson et al.   BIOESSAYS

OpenCFU, a New Free and Open-Source Software to Count Cell Colonies and Other Circular Objects

(2013) Quentin Geissmann   PLoS One

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration

(2012) Sandra Cristea et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mapping protein interactions by combining antibody affinity maturation and mass spectrometry

(2011) Michael R. Dyson et al.   ANALYTICAL BIOCHEMISTRY

Identification of HBsAg-specific antibodies from a mammalian cell displayed full-length human antibody library of healthy immunized donor

(2011) Chang-Zheng Li et al.   Cellular & Molecular Immunology

Beyond natural antibodies: the power of in vitro display technologies

(2011) Andrew R M Bradbury et al.   NATURE BIOTECHNOLOGY

TAL Effectors: Customizable Proteins for DNA Targeting

(2011) A. J. Bogdanove et al.   SCIENCE

Development of a novel mammalian cell surface antibody display platform

(2010) Chen Zhou et al.   mAbs

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS