期刊
JOURNAL OF THERMAL BIOLOGY
卷 82, 期 -, 页码 186-196出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtherbio.2019.04.009
关键词
brown fat; Skin temperature; Thermoregulation
资金
- Spanish Ministry of Economy and Competitiveness via the Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III [PI13/01393]
- Retos de la Sociedad [DEP2016-79512-R, PTA 12264-I]
- European Regional Development Fund (ERDF)
- Spanish Ministry of Education [FPU 13/04365, FPU14/04172, FPU15/05337, FPU15/04059]
- Spanish Ministry of Science and Innovation-MINECO [RYC-2014-16938]
- Fundacion Iberoamericana de Nutricion (FINUT)
- Redes Tematicas de Investigacion Cooperative RETIC (Red SAMID) [RD16/0022]
- AstraZeneca HealthCare Foundation
- University of Granada Plan Propio de Investigacion 2016 - Excellence actions: Unit of Excellence on Exercise and Health (UCEES)
- University of Granada Plan Propio de Investigacion 2018 - Programa Contratos-Puente
- Junta de Andalucia, Consejeria de Conocimiento, Investigacion y Universidades (ERDF) [SOMM17/6107/UGR]
Brown adipose tissue (BAT) thermogenic activity is commonly assessed with a positron emission tomography with computed tomography scan (PET/CT). This technique has several limitations and alternative techniques are needed. Supraclavicular skin temperature measured with iButtons and infrared thermography (IRT) has been proposed as an indirect marker of BAT activity. We studied the concurrent validity of skin temperature measured with iButtons vs. IRT and the association of supraclavicular skin temperature measured with iButtons and IRT with BAT. We measured skin temperature upon a shivering threshold test with iButtons and IRT in 6 different regions in 12 participants (n = 2 men). On a separate day, we determined supraclavicular skin temperature with an iButton and IRT after 2 h of a personalized cooling protocol. Thereafter, we quantified BAT volume and activity by PET/CT. We observed that the absolute differences between the devices were statistically different from 0 (all P < 0.05) after the shivering threshold test. Moreover, we did not find any association between supraclavicular skin temperature measured with iButtons or IRT and BAT F-18-FDG activity (r = -0.213; P = 0.530 and r = -0.079; P = 0.817). However, we observed a negative association of supraclavicular skin temperature measured by IRT with BAT F-18-FDG volume (r = -0.764; P = 0.006), but not with supraclavicular skin temperature measured with iButtons (r = -0.546; P = 0.082). In light of these results, we concluded that the measurement of skin temperature obtained by iButtons and IRT are not comparable. Furthermore, it seems that supraclavicular skin temperature is not associated with BAT F-18-FDG activity, but it appears to be negatively associated with BAT F-18-FDG volume in the case of IRT.
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