Metabolically healthy obesity across the life course: epidemiology, determinants, and implications

Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver Disease

(2016) Yoosoo Chang et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Obesity or obesities? Controversies on the association between body mass index and premature mortality

(2016) Ottavio Bosello et al.   Eating and Weight Disorders-Studies on Anorexia Bulimia and Obesity

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY

(2016) W. Timothy Garvey et al.   Endocrine Practice

Mediterranean diet and mortality risk in metabolically healthy obese and metabolically unhealthy obese phenotypes

(2016) Y-M Park et al.   INTERNATIONAL JOURNAL OF OBESITY

Identification of Genetic and Environmental Factors Predicting Metabolically Healthy Obesity in Children: Data From the BCAMS Study

(2016) Lujiao Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cardiometabolic Health in Obese Adolescents Is Related to Length of Obesity Exposure: A Pilot Study

(2016) Hana Zamrazilova et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Fatty liver index is a risk determinant of incident type 2 diabetes in a metabolically healthy population with obesity

(2016) Chang Hee Jung et al.   Obesity

Proinflammatory and lipid biomarkers mediate metabolically healthy obesity: A proteomics study

(2016) Ayo Priscille Doumatey et al.   Obesity

Metabolically Healthy Obesity: Personalised and Public Health Implications

(2016) Catherine M. Phillips   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Does Metabolically Healthy Obesity Exist?

(2016) Araceli Muñoz-Garach et al.   Nutrients

Hepatic fat content is a determinant of metabolic phenotypes and increased carotid intima-media thickness in obese adults

(2016) Huijie Zhang et al.   Scientific Reports

Divergent associations of height with cardiometabolic disease and cancer: epidemiology, pathophysiology, and global implications

(2016) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Physical Activity and Sedentary Behavior in Metabolically Healthy versus Unhealthy Obese and Non-Obese Individuals – The Maastricht Study

(2016) Belle H. de Rooij et al.   PLoS One

Is the Metabolically Healthy Obesity Phenotype an Irrelevant Artifact for Public Health?

(2015) Juan Pablo Rey-López et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Invited Commentary: Limitations and Usefulness of the Metabolically Healthy Obesity Phenotype

(2015) Patrick T. Bradshaw et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Lipoprotein particle subclass profiles among metabolically healthy and unhealthy obese and non-obese adults: Does size matter?

(2015) Catherine M. Phillips et al.   ATHEROSCLEROSIS

Stability of metabolically healthy obesity over 8 years: the English Longitudinal Study of Ageing

(2015) Mark Hamer et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Preserved insulin sensitivity predicts metabolically healthy obese phenotype in children and adolescents

(2015) Rade Vukovic et al.   EUROPEAN JOURNAL OF PEDIATRICS

Prevalence of Metabolically Healthy Obese and Metabolically Obese but Normal Weight in Adults Worldwide: A Meta-Analysis

(2015) B. Wang et al.   HORMONE AND METABOLIC RESEARCH

Strong Effect of Pubertal Status on Metabolic Health in Obese Children: A Longitudinal Study

(2015) Thomas Reinehr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolically normal obese people are protected from adverse effects following weight gain

(2015) Elisa Fabbrini et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolically Healthy Obesity Is Not Associated with Food Intake in White or Black Men

(2015) Ruth W Kimokoti et al.   JOURNAL OF NUTRITION

Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences

(2015) Mariangela Rondanelli et al.   Lipids in Health and Disease

Genetic Effects on Longitudinal Changes from Healthy to Adverse Weight and Metabolic Status — The HUNT Study

(2015) Kirsti Kvaløy et al.   PLoS One

Healthy eating index and metabolically healthy obesity in U.S. adolescents and adults

(2015) Sarah M. Camhi et al.   PREVENTIVE MEDICINE

Physical Activity and Cardiorespiratory Fitness as Major Markers of Cardiovascular Risk: Their Independent and Interwoven Importance to Health Status

(2015) Jonathan Myers et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Role of Fitness in the Metabolically Healthy but Obese Phenotype: A Review and Update

(2015) Francisco B. Ortega et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Depressive symptoms, anxiety and well-being among metabolic health obese subtypes

(2015) Catherine M. Phillips et al.   PSYCHONEUROENDOCRINOLOGY

Assessing cardiometabolic risk in middle-aged adults using body mass index and waist–height ratio: are two indices better than one? A cross-sectional study

(2015) Seán R. Millar et al.   Diabetology & Metabolic Syndrome

The Relationship between Dietary Patterns and Metabolic Health in a Representative Sample of Adult Australians

(2015) Lucinda Bell et al.   Nutrients

Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals

(2015) A. Berezina et al.   Biomed Research International

Trends and prevalence of overweight and obesity in primary school aged children in the Republic of Ireland from 2002-2012: a systematic review

(2014) Eimear Keane et al.   BMC PUBLIC HEALTH

Predictors of Metabolically Healthy Obesity in Children

(2014) Rhiannon L. Prince et al.   DIABETES CARE

American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the 2014 Advanced Framework for a New Diagnosis of Obesity as a Chronic Disease

(2014) W. Garvey et al.   Endocrine Practice

Metabolically healthy obesity and the risk of cardiovascular disease and type 2 diabetes: the Whitehall II cohort study

(2014) Guy-Marino Hinnouho et al.   EUROPEAN HEART JOURNAL

High aerobic fitness in late adolescence is associated with a reduced risk of myocardial infarction later in life: a nationwide cohort study in men

(2014) Gabriel Högström et al.   EUROPEAN HEART JOURNAL

Natural course of metabolically healthy abdominal obese adults after 10 years of follow-up: the Tehran Lipid and Glucose Study

(2014) R Eshtiaghi et al.   INTERNATIONAL JOURNAL OF OBESITY

Predicting the development of the metabolically healthy obese phenotype

(2014) I Achilike et al.   INTERNATIONAL JOURNAL OF OBESITY

Metabolically Healthy Obesity, Presence or Absence of Fatty Liver, and Risk of Type 2 Diabetes in Japanese Individuals: Toranomon Hospital Health Management Center Study 20 (TOPICS 20)

(2014) Yoriko Heianza et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Is it Finally Time to Dispel the Concept of Metabolically-Healthy Obesity?∗

(2014) Rishi Puri   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Metabolically healthy obesity from childhood to adulthood — Does weight status alone matter?

(2014) Susann Blüher et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014) Gerald I. Shulman   NEW ENGLAND JOURNAL OF MEDICINE

Adipose tissue dysregulation and metabolic consequences in childhood and adolescent obesity: potential impact of dietary fat quality

(2014) Aoibheann M. McMorrow et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

(2014) Jana V van Vliet-Ostaptchouk et al.   BMC Endocrine Disorders

Do rapid BMI growth in childhood and early-onset obesity offer cardiometabolic protection to obese adults in mid-life? Analysis of a longitudinal cohort study of Danish men

(2014) Laura D Howe et al.   BMJ Open

A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype

(2014) Lance Dalleck et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

A Weight Loss Diet Intervention Has a Similar Beneficial Effect on Both Metabolically Abnormal Obese and Metabolically Healthy but Obese Premenopausal Women

(2013) Jonatan R. Ruiz et al.   ANNALS OF NUTRITION AND METABOLISM

Metabolically Healthy Obesity and Risk of Mortality: Does the definition of metabolic health matter?

(2013) G.-M. Hinnouho et al.   DIABETES CARE

Diabetes and Cardiovascular Disease Outcomes in the Metabolically Healthy Obese Phenotype: A cohort study

(2013) S. L. Appleton et al.   DIABETES CARE

Tipping the inflammatory balance: inflammasome activation distinguishes metabolically unhealthy from healthy obesity

(2013) Rinke Stienstra et al.   DIABETOLOGIA

Determinants of the transition from a cardiometabolic normal to abnormal overweight/obese phenotype in a Spanish population

(2013) Helmut Schröder et al.   EUROPEAN JOURNAL OF NUTRITION

High Risk vs. “Metabolically Healthy” Phenotype in Juvenile Obesity - Neck Subcutaneous Adipose Tissue and Serum Uric Acid are Clinically Relevant

(2013) D. Weghuber et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories

(2013) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Does Inflammation Determine Metabolic Health Status in Obese and Nonobese Adults?

(2013) Catherine M. Phillips et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolically Healthy but Obese, a Matter of Time? Findings From the Prospective Pizarra Study

(2013) Federico Soriguer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolically obese status with normal weight is associated with both the prevalence and severity of angiographic coronary artery disease

(2013) Beom-June Kwon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolically healthy obese subjects are at risk of fatty liver but not of pre-clinical atherosclerosis

(2013) Ki-Chul Sung et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Influence of a clinical lifestyle-based weight loss program on the metabolic risk profile of metabolically normal and abnormal obese adults

(2013) Rebecca H. Liu et al.   Obesity

Diet composition and activity level of at risk and metabolically healthy obese american adults

(2013) Arlene L. Hankinson et al.   Obesity

Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype

(2013) Catherine M. Phillips et al.   Obesity

Uric acid best predicts metabolically unhealthy obesity with increased cardiovascular risk in youth and adults

(2013) Harald Mangge et al.   Obesity

Relationships of body composition and liver fat content with insulin resistance in obesity-matched adolescents and adults

(2013) Katarzyna Linder et al.   Obesity

Cardiorespiratory Fitness and Adiposity in Metabolically Healthy Overweight and Obese Youth

(2013) M. Senechal et al.   PEDIATRICS

Defining Metabolically Healthy Obesity: Role of Dietary and Lifestyle Factors

(2013) Catherine M. Phillips et al.   PLoS One

Metabolically healthy obesity: Definitions, determinants and clinical implications

(2013) Catherine M. Phillips   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications

(2013) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Relation of Childhood Obesity/Cardiometabolic Phenotypes to Adult Cardiometabolic Profile: The Bogalusa Heart Study

(2012) S. Li et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Body Fat Distribution and Risk of Cardiovascular Disease

(2012) Jean-Pierre Després   CIRCULATION

The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness

(2012) Francisco B. Ortega et al.   EUROPEAN HEART JOURNAL

Insulin-sensitive obese children display a favorable metabolic profile

(2012) Rade Vukovic et al.   EUROPEAN JOURNAL OF PEDIATRICS

Cohort Profile: The International Childhood Cardiovascular Cohort (i3C) Consortium

(2012) T. Dwyer et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Metabolically Healthy Obesity and Risk of All-Cause and Cardiovascular Disease Mortality

(2012) Mark Hamer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Childhood Obesity and Vascular Phenotypes

(2012) Marietta Charakida et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Burden of subclinical cardiovascular disease in “metabolically benign” and “at-risk” overweight and obese women: The Study of Women's Health Across the Nation (SWAN)

(2011) Unab I. Khan et al.   ATHEROSCLEROSIS

Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity

(2011) J Gómez-Ambrosi et al.   INTERNATIONAL JOURNAL OF OBESITY

Evidence that the prevalence of childhood overweight is plateauing: data from nine countries

(2011) Tim Olds et al.   International Journal of Pediatric Obesity

Preadipocyte Factor-1 Is Associated with Metabolic Profile in Severe Obesity

(2011) J. O'Connell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dysmetabolic signals in “metabolically healthy” obesity

(2011) Peter Manu et al.   Obesity Research & Clinical Practice

Insulin-sensitive obesity

(2010) Nora Klöting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effects of Weight Loss Among Metabolically Healthy Obese Men and Women

(2010) P. M. Janiszewski et al.   DIABETES CARE

Impact of BMI and the Metabolic Syndrome on the Risk of Diabetes in Middle-Aged Men

(2010) J. Arnlov et al.   DIABETES CARE

Prevalence, Metabolic Features, and Prognosis of Metabolically Healthy Obese Italian Individuals: The Cremona Study

(2010) G. Calori et al.   DIABETES CARE

Effects of a lifestyle intervention in metabolically benign and malign obesity

(2010) K. Kantartzis et al.   DIABETOLOGIA

Metabolically healthy obesity: different prevalences using different criteria

(2010) S Velho et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review

(2010) J J Reilly et al.   INTERNATIONAL JOURNAL OF OBESITY

Childhood Obesity, Other Cardiovascular Risk Factors, and Premature Death

(2010) Paul W. Franks et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Prevalence of Metabolically Healthy Obese Subjects Defined by BMI and Dual-Energy X-Ray Absorptiometry

(2010) Jennifer L. Shea et al.   Obesity

Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1interact with plasma saturated fatty acids to modulate insulin resistance

(2009) Jane F Ferguson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Are Metabolically Normal but Obese Individuals at Lower Risk for All-Cause Mortality?

(2009) J. L. Kuk et al.   DIABETES CARE

Physical Fitness During Adolescence and Adult Mortality

(2009) Mutsumi Sato et al.   EPIDEMIOLOGY

Acylated and nonacylated ghrelin levels and their associations with insulin resistance in obese and normal weight children with metabolic syndrome

(2009) Lucia Pacifico et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women

(2009) Satoru Kodama   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Leptin Receptor Polymorphisms Interact with Polyunsaturated Fatty Acids to Augment Risk of Insulin Resistance and Metabolic Syndrome in Adults

(2009) Catherine M. Phillips et al.   JOURNAL OF NUTRITION

Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

(2009) E. Fabbrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Characterization of Metabolically Benign Obesity in Humans

(2008) Norbert Stefan   ARCHIVES OF INTERNAL MEDICINE

The Obese Without Cardiometabolic Risk Factor Clustering and the Normal Weight With Cardiometabolic Risk Factor Clustering

(2008) Rachel P. Wildman   ARCHIVES OF INTERNAL MEDICINE

Inclusion of C-reactive protein in the identification of metabolically healthy but obese (MHO) individuals

(2008) A.D. Karelis et al.   DIABETES & METABOLISM

High Birth Weight and Early Postnatal Weight Gain Protect Obese Children and Adolescents From Truncal Adiposity and Insulin Resistance: Metabolically healthy but obese subjects?

(2008) N. Bouhours-Nouet et al.   DIABETES CARE

Metabolically healthy but obese women: effect of an energy-restricted diet

(2008) A. D. Karelis et al.   DIABETOLOGIA

Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects

(2008) Kevin M. Korenblat et al.   GASTROENTEROLOGY

Global burden of obesity in 2005 and projections to 2030

(2008) T Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

High Adiponectin Concentrations Are Associated with the Metabolically Healthy Obese Phenotype

(2008) Carlos A. Aguilar-Salinas et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM