Use of Allogeneic Hypoxic Mesenchymal Stem Cells For Treating Disc Degeneration in Rabbits

Human bone morphogenetic protein 7 transfected nucleus pulposus cells delay the degeneration of intervertebral disc in dogs

(2017) Tao Gu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy

(2017) Christopher Centeno et al.   Journal of Translational Medicine

Effect of the adenovirus-mediated Wip1 gene on lumbar intervertebral disc degeneration in a rabbit model

(2017) Yuan Wang et al.   Molecular Medicine Reports

BMP7 enhances the effect of BMSCs on extracellular matrix remodeling in a rabbit model of intervertebral disc degeneration

(2016) Jun Xu et al.   FEBS Journal

Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study

(2016) Christian Elabd et al.   Journal of Translational Medicine

Allogeneic Mesenchymal Stem Cells in Combination with Hyaluronic Acid for the Treatment of Osteoarthritis in Rabbits

(2016) En-Rung Chiang et al.   PLoS One

Mesenchymal Stem Cells Reduce Intervertebral Disc Fibrosis and Facilitate Repair

(2014) Victor Y.L. Leung et al.   STEM CELLS

Hypoxic mesenchymal stem cells engraft and ameliorate limb ischaemia in allogeneic recipients

(2013) Wei-Hua Huang et al.   CARDIOVASCULAR RESEARCH

In search of nucleus pulposus-specific molecular markers

(2013) F. Lv et al.   RHEUMATOLOGY

Hypoxia preconditioned bone marrow mesenchymal stem cells promoted liver regeneration in a rat massive hepatectomy model

(2013) Jun Yu et al.   Stem Cell Research & Therapy

The pathogenesis of degeneration of the intervertebral disc and emerging therapies in the management of back pain

(2012) S. P. F. Hughes et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Enhancement of Wound Healing by Human Multipotent Stromal Cell Conditioned Medium: The Paracrine Factors and p38 MAPK Activation

(2011) Tu-Lai Yew et al.   CELL TRANSPLANTATION

Transplantation of mesenchymal stem cells and nucleus pulposus cells in a degenerative disc model in rabbits: a comparison of 2 cell types as potential candidates for disc regeneration

(2011) Ganjun Feng et al.   JOURNAL OF NEUROSURGERY-SPINE

Effects of adeno-associated virus-2-mediated human BMP-7 gene transfection on the phenotype of nucleus pulposus cells

(2011) Chaofeng Wang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Intervertebral Disc Repair by Autologous Mesenchymal Bone Marrow Cells: A Pilot Study

(2011) Lluis Orozco et al.   TRANSPLANTATION

Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST

(2010) C.-C. Tsai et al.   BLOOD

Periodic knee injections of BMP-7 delay cartilage degeneration induced by excessive running in rats

(2009) Ichiro Sekiya et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mesenchymal Stem Cells Arrest Intervertebral Disc Degeneration Through Chondrocytic Differentiation and Stimulation of Endogenous Cells

(2009) Fan Yang et al.   MOLECULAR THERAPY

BMP-7 protects against progression of cartilage degeneration after impact injury

(2008) Mark Hurtig et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Weekly intra-articular injections of bone morphogenetic protein-7 inhibits osteoarthritis progression

(2008) Masaya Hayashi et al.   ARTHRITIS RESEARCH & THERAPY

Bone morphogenetic protein-7 protects human intervertebral disc cells in vitro from apoptosis

(2007) Aiqun Wei et al.   Spine Journal