Review
Food Science & Technology
Laryssa Rosa de Sousa Franckilin, Anna Clara Paiva Menezes Dos Santos, Flavio Eduardo Dias Araujo Freitas, Isabela Garbazza Vieira, Carlos Eduardo de Freitas Jorge, Daniela Godoy Neri, Maria Vitoria Cota de Abreu, Janaina Koenen Fonseca, Renato Guimaraes Loffi, Giselle Foureaux
Summary: Gluten, the most common protein in wheat, is associated with celiac disease, wheat allergy, and non-celiac gluten sensitivity. These disorders have similar clinical manifestations but differ in development pathways and diagnostic criteria. A gluten-free diet is the most effective treatment for celiac disease and may also lead to improvements in neuropathologies and the gut microbiome.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Guifeng Xu, Buyun Liu, Wenhan Yang, Linda G. Snetselaar, Mingwu Chen, Wei Bao, Lane Strathearn
Summary: This study found a significant association of common allergic conditions (food allergy, respiratory allergy, and skin allergy) with ADHD in a nationally representative sample of US children aged 4-17 years.
Article
Behavioral Sciences
Renee M. Gardner, Ida Samuelsson, Emily G. Severance, Hugo Sjoqvist, Robert H. Yolken, Christina Dalman, Hakan Karlsson
Summary: This study found little association between maternal antibodies against components of gluten and the risk of ASD in general. Exposure to high levels of AGA in the pre- and perinatal periods may be protective in terms of risk for ASD with ID.
Review
Food Science & Technology
Kalekristos Yohannes Woldemariam, Juanli Yuan, Zhen Wan, Qinglin Yu, Yating Cao, Huijia Mao, Yingli Liu, Jing Wang, Hongyan Li, Baoguo Sun
Summary: Wheat mainly consists of gluten with 30% gliadin and 50% glutenin, which are associated with celiac disease. The challenge lies in discovering new gluten-based peptides with high affinity toward T-cells. The highly immunogenic 33-mer gliadin peptide is considered the main cause, so consistent data on different gluten peptides and their immunogenicity is urgently needed.
FOOD REVIEWS INTERNATIONAL
(2022)
Article
Multidisciplinary Sciences
Xuemei Jin, Huilin Zhu, Wei Cao, Xiaobing Zou, Jiajia Chen
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 2% of children. A computer vision-based motion trajectory detection approach was proposed in this study to objectively extract movement features (MFs) from videos and evaluate children's activity levels in ASD assessment. The most relevant MFs were found to be the pixel distance (PD)-based MFs of all three body key points and the instantaneous pixel velocity (IPV)-based MFs of the right wrist key point in Table-play activity, which can be used as an auxiliary means for automating the evaluation of activity levels in ASD assessment.
SCIENTIFIC REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Silvia Alemany, Claudia Avella-Garcia, Zeyan Liew, Raquel Garcia-Esteban, Kosuke Inoue, Tim Cadman, Monica Lopez-Vicente, Llucia Gonzalez, Isolina Riano Galan, Ainara Andiarena, Maribel Casas, Katerina Margetaki, Katrine Strandberg-Larsen, Deborah A. Lawlor, Hanan El Marroun, Henning Tiemeier, Carmen Iniguez, Adonina Tardon, Loreto Santa-Marina, Jordi Julvez, Daniela Porta, Leda Chatzi, Jordi Sunyer
Summary: The study found that children prenatally exposed to acetaminophen were more likely to have borderline or clinical ASC and ADHD symptoms in the future. The association was slightly stronger among boys, but postnatal exposure to acetaminophen did not show any significant association with ASC or ADHD symptoms. The results support the need to provide clear information to pregnant women and their partners about the potential risks of acetaminophen use.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Christoph Buehrer, Stefanie Endesfelder, Till Scheuer, Thomas Schmitz
Summary: Paracetamol, commonly used during pregnancy for fever and pain, is suspected to increase the risk of attention deficit hyperactivity disorder and autism spectrum disorder in offspring by about 25% according to epidemiological studies. However, there are still unknown factors and mechanisms that require further investigation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Rachel U. Lee, Shauna L. Stahlman, Jared S. Magee
Summary: This article describes the epidemiology of celiac disease in the US military population. A population-based study was conducted using data from 2000 to 2021, revealing an increasing trend in incidence and prevalence rates.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Genetics & Heredity
Holly K. Harris, Tojo Nakayama, Jenny Lai, Boxun Zhao, Nikoleta Argyrou, Cynthia S. Gubbels, Aubrie Soucy, Casie A. Genetti, Victoria Suslovitch, Lance H. Rodan, George E. Tiller, Gaetan Lesca, Karen W. Gripp, Reza Asadollahi, Ada Hamosh, Carolyn D. Applegate, Peter D. Turnpenny, Marleen E. H. Simon, Catharina M. L. Volker-Touw, Koen L. I. van Gassen, Ellen van Binsbergen, Rolph Pfundt, Thatjana Gardeitchik, Bert B. A. de Vries, LaDonna L. Immken, Catherine Buchanan, Marcia Willing, Tomi L. Toler, Emily Fassi, Laura Baker, Fleur Vansenne, Xiadong Wang, Julian L. Ambrus, Madeleine Fannemel, Jennifer E. Posey, Emanuele Agolini, Antonio Novelli, Anita Rauch, Paranchai Boonsawat, Christina R. Fagerberg, Martin J. Larsen, Maria Kibaek, Audrey Labalme, Alice Poisson, Katelyn K. Payne, Laurence E. Walsh, Kimberly A. Aldinger, Jorune Balciuniene, Cara Skraban, Christopher Gray, Jill Murrell, Caleb P. Bupp, Giulia Pascolini, Paola Grammatico, Martin Broly, Sebastien Kury, Mathilde Nizon, Iqra Ghulam Rasool, Muhammad Yasir Zahoor, Cornelia Kraus, Andre Reis, Muhammad Iqbal, Kevin Uguen, Severine Audebert-Bellanger, Claude Ferec, Sylvia Redon, Janice Baker, Yunhong Wu, Guiseppe Zampino, Steffan Syrbe, Ines Brosse, Rami Abou Jamra, William B. Dobyns, Lilian L. Cohen, Anne Blomhoff, Cyril Mignot, Boris Keren, Thomas Courtin, Pankaj B. Agrawal, Alan H. Beggs, Timothy W. Yu
Summary: These individuals with de novo or inherited deleterious variants in RFX3, RFX4, and RFX7 share neurobehavioral features including ASD, intellectual disability, and/or ADHD, as well as hypersensitivity to sensory stimuli and sleep problems. The RFX family genes are strongly expressed in developing and adult human brain, with enriched X-box binding motifs and RFX ChIP-seq peaks in the cis-regulatory regions of known ASD risk genes, indicating a likely role of these genes in cases of monogenic intellectual disability, ADHD, and ASD.
GENETICS IN MEDICINE
(2021)
Article
Genetics & Heredity
Ditte Demontis, G. Bragi Walters, Georgios Athanasiadis, Raymond Walters, Karen Therrien, Trine Tollerup Nielsen, Leila Farajzadeh, Georgios Voloudakis, Jaroslav Bendl, Biau Zeng, Wen Zhang, Jakob Grove, Thomas D. Als, Jinjie Duan, F. Kyle Satterstrom, Jonas Bybjerg-Grauholm, Marie Baekved-Hansen, Olafur O. Gudmundsson, Sigurdur H. Magnusson, Gisli Baldursson, Katrin Davidsdottir, Gyda S. Haraldsdottir, Esben Agerbo, Gabriel E. Hoffman, Soren Dalsgaard, Joanna Martin, Marta Ribases, Dorret Boomsma, Maria Soler Artigas, Nina Roth Mota, Daniel Howrigan, Sarah E. Medland, Tetyana Zayats, Veera M. Rajagopal, Merete Nordentoft, Ole Mors, David M. Hougaard, Preben Bo Mortensen, Mark J. Daly, Stephen Faraone, Hreinn Stefansson, Panos Roussos, Barbara Franke, Thomas Werge, Benjamin M. Neale, Kari Stefansson, Anders D. Borglum
Summary: This study conducted a meta-analysis of genome-wide association studies on ADHD and identified 27 significant genetic loci associated with ADHD. They also found that these loci were enriched with genes involved in early brain development. Moreover, they discovered an increased load of rare protein-truncating variants in ADHD, implicating SORCS3 as a potential gene involved in ADHD.
Article
Public, Environmental & Occupational Health
Lonny Stokholm, Mette Juhl, Nicole M. Talge, Mika Gissler, Carsten Obel, Katrine Strandberg-Larsen
Summary: This study examined the association between prenatal exposure to obstetric oxytocin and ADHD and ASD in children born in Denmark and Finland. While initial analyses showed a slight increase in risk, adjustments for confounding factors attenuated the association. The results suggest that the link is unlikely to be causal, alleviating concerns about using oxytocin in obstetric settings leading to ADHD or ASD.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Neurosciences
Grace R. Jacobs, Aristotle N. Voineskos, Colin Hawco, Laura Stefanik, Natalie J. Forde, Erin W. Dickie, Meng-Chuan Lai, Peter Szatmari, Russell Schachar, Jennifer Crosbie, Paul D. Arnold, Anna Goldenberg, Lauren Erdman, Stephanie H. Ameis
Summary: This study integrated brain imaging and behavioral measures to identify new brain-behavior subgroups cutting across autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD). The new groups showed significantly different scores on everyday adaptive functioning, indicating potential for studying data-driven groups representing children with neurodevelopmental disorders more similar to each other than others within their own diagnostic group.
NEUROPSYCHOPHARMACOLOGY
(2021)
Article
Psychiatry
Doha Bemmouna, Sebastien Weibel, Markus Kosel, Roland Hasler, Luisa Weiner, Nader Perroud
Summary: The co-occurrence of ADHD and ASD in adults is common. The utility of the AQ as a screening tool for ASD in the context of ADHD is limited, but the imagination subscale can be useful for distinguishing between individuals with ADHD and ASD.
PSYCHIATRY RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Francesca Fiori Nastro, Maria Rosaria Serra, Sabrina Cenni, Daniela Pacella, Massimo Martinelli, Erasmo Miele, Annamaria Staiano, Carlo Tolone, Renata Auricchio, Caterina Strisciuglio
Summary: This study aimed to assess the prevalence of FGIDs in children with CD after 1 year of follow-up and to compare the prevalence of FGIDs in children with CD on a GFD with processed foods and in children on a GFD with natural products.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Multidisciplinary Sciences
Kristine Kaalund-Brok, Tine Bodil Houmann, Marie Bang Hebsgaard, Maj-Britt Glenn Lauritsen, Louise Hyldborg Lundstrom, Helene Gronning, Lise Darling, Susanna Reinert-Petersen, Morten Aagaard Petersen, Jens Richardt Mollegaard Jepsen, Anne Katrine Pagsberg, Kerstin Jessica Plessen, Henrik Berg Rasmussen, Pia Jeppesen
Summary: Randomized placebo-controlled trials have shown the efficacy of methylphenidate (MPH) for ADHD, but selection biases may limit generalizability. A study on 207 children with ADHD found that 81.2% responded favorably to carefully titrated MPH treatment with minimal adverse effects.
Article
Medicine, General & Internal
Marcela Bejares, Amaya Oyarzun, Yalda Lucero, Nelly Espinoza, Karla Bascunan, Magdalena Araya
REVISTA MEDICA DE CHILE
(2015)
Article
Gastroenterology & Hepatology
Sergio George, Nora Mamani, Yalda Lucero, Juan Pablo Torres, Mauricio Farfan, Anne J. Lagomarcino, Andrea Orellana, Miguel O'Ryan
Article
Gastroenterology & Hepatology
Francisco Alliende, Cecilia Vial, Karen Espinoza, Daniela Schnettle, Victoria Romero, Isabel Miquel, Maria E. Arancibia, Gloria Rios, Lorena Rodriguez, Soledad Quesada, Yalda Lucero, Gabriela M. Repetto
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2016)
Article
Immunology
Andrea Orellana-Manzano, Miguel G. O'Ryan, Anne J. Lagomarcino, Sergio George, Mindy S. Munoz, Nora Mamani, Carolina A. Serrano, Paul R. Harris, Octavio Ramilo, Asuncion Mejias, Juan P. Torres, Yalda Lucero, Andrew F. G. Quest
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2016)
Article
Immunology
Yalda Lucero, Roberto Vidal, Miguel O'Ryan G
Article
Immunology
Yalda Lucero, Amaya Oyarzun, Miguel O'Ryan, Rodrigo Quera, Nelly Espinosa, Romina Valenzuela, Daniela Simian, Elisa Alcalde, Claudio Arce, Mauricio J. Farfan, ALejandra F. Vergara, Ivan Gajardo, Jocelyn Mendez, Jorge Carrasco, German Errazuriz, Monica Gonzalez, Juan C. Ossa, Eduardo Maiza, Francisco Perez-Bravo, Magdalena Castro, Magdalena Araya
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2017)
Correction
Immunology
Yalda Lucero, Amaya Oyarzun, Miguel O'Ryan, Rodrigo Quera, Nelly Espinosa, Romina Valenzuela, Daniela Simian, Elisa Alcalde, Claudio Arce, Mauricio J. Farfan, Alejandra F. Vergara, Ivan Gajardo, Jocelyn Mendez, Jorge Carrasco, German Errazuriz, Monica Gonzalez, Juan C. Ossa, Eduardo Maiza, Francisco Perez-Bravo, Magdalena Castro, Magdalena Araya
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2017)
Article
Gastroenterology & Hepatology
Magdalena Araya, Julia Diaz, Amaya Oyarzun, Yalda Lucero, Teresa Alarcon, Monica Gonzalez, Paulina Canales, Liliana Fierro, Francisco Perez-Bravo
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2018)
Article
Pediatrics
Yalda Lucero, Miguel O'Ryan, Giulia Liparoti, Nicole Huerta, Nora Mamani, Sasirekha Ramani, Anne J. Lagomarcino, Felipe Del Canto, Jorge Quense
JOURNAL OF PEDIATRICS
(2019)
Article
Infectious Diseases
Yalda Lucero, Anne J. Lagomarcino, Monica Espinoza, Nanami Kawakami, Nora Mamani, Nicole Huerta, Felipe Del Canto, Mauricio Farfan, Yoshihiro Sawaguchi, Sergio George, Miguel O. ' Ryan
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2020)
Article
Gastroenterology & Hepatology
Yalda Lucero, Anne J. Lagomarcino, Juan P. Torres, Patricia Roessler, Nora Mamani, Sergio A. George, Nicole Huerta, Monica Gonzalez, Miguel G. O'Ryan
Summary: The study included 61 school-aged children undergoing H. pylori eradication therapy, with a high eradication rate and good tolerance observed in the treatment group. Significant reductions in serum markers PGI and PGII levels were noted post-eradication. Despite a small percentage experiencing reinfection, no significant difference in symptoms was observed between the treated and control groups.
Article
Pediatrics
German Errazuriz, Yalda Lucero, Sergio Ceresa, Monica Gonzalez, Maureen Rossel, Andres Vives
REVISTA CHILENA DE PEDIATRIA-CHILE
(2016)
Article
Pediatrics
Isabel Miquel, Maria Eugenia Arancibia, Francisco Alliende, Gloria Rios, Lorena Rodriguez, Yalda Lucero, Eric Saelzer
REVISTA CHILENA DE PEDIATRIA-CHILE
(2017)
Review
Pediatrics
Catalina Ortiz, Romina Valenzuela, Yalda Lucero A
REVISTA CHILENA DE PEDIATRIA-CHILE
(2017)