Article
Gastroenterology & Hepatology
Lena W. Y. Thin, Sherman Picardo, Shanela Sooben, Kevin Murray, Jennifer Ryan, Marina H. Wallace
Summary: The study compared the risk of early post-operative endoscopic recurrence in Crohn's disease patients undergoing end-to-end anastomosis (ETEA) versus side-to-side anastomosis (STSA). The results showed that in emergency surgeries, ETEA was associated with a higher risk of EPER, while early initiation of biologics and/or immunosuppressants and smoking cessation were crucial for this high-risk group of patients.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Medicine, General & Internal
Michela Mineccia, Giovanni Maconi, Marco Daperno, Maria Cigognini, Valeria Cherubini, Francesco Colombo, Serena Perotti, Caterina Baldi, Paolo Massucco, Sandro Ardizzone, Alessandro Ferrero, Gianluca M. Sampietro
Summary: The results of the Remedy study suggest that mesenteric removal during surgery for ileocolic CD does not have a significant impact on postoperative complications, endoscopic and ultrasonographic recurrences, and long-term surgical recurrence.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Gabriele Bislenghi, Peter-Jan Vancoillie, Steffen Fieuws, Bram Verstockt, Joao Sabino, Albert Wolthuis, Andre D'Hoore
Summary: This study compared the outcomes of side-to-side (S-S) and end-to-end (E-E) anastomosis after ileocecal resection in Crohn's disease patients. The results showed no significant differences in postoperative complications and endoscopic recurrence between the two anastomosis types. However, the S-S anastomosis significantly reduced the risk of surgical and endoscopic reintervention in the long term.
UPDATES IN SURGERY
(2023)
Article
Gastroenterology & Hepatology
Gabriele Bislenghi, Julie Van Den Bossch, Steffen Fieuws, Albert Wolthuis, Marc Ferrante, Gert de Hertogh, Severine Vermeire, Andre D'Hoore
Summary: The macroscopic appearance of the bowel and associated mesentery during surgery does not appear to be predictive of postoperative recurrence after ileocecal resection for Crohn's disease. Prospective studies investigating risk factors for Crohn's disease recurrence after surgery are scarce.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Gastroenterology & Hepatology
Henit Yanai, Anna Kagramanova, Oleg Knyazev, Joao Sabino, Shana Haenen, Gerassimos J. Mantzaris, Katerina Mountaki, Alessandro Armuzzi, Daniela Pugliese, Federica Furfaro, Gionata Fiorino, David Drobne, Tina Kurent, Sharif Yassin, Nitsan Maharshak, Fabiana Castiglione, Roberto de Sire, Olga Maria Nardone, Klaudia Farkas, Tamas Molnar, Zeljko Krznaric, Marko Brinar, Elena Chashkova, Moran Livne Margolin, Uri Kopylov, Cristina Bezzio, Ariella Bar-Gil Shitrit, Milan Lukas, Maria Chaparro, Marie Truyens, Stephane Nancey, Triana Lobaton, Javier P. Gisbert, Simone Saibeni, Peter Bacsur, Peter Bossuyt, Julien Schulberg, Frank Hoentjen, Chiara Vigano, Andrea Palermo, Joana Torres, Joana Reves, Konstantinos Karmiris, Magdalini Velegraki, Edoardo Savarino, Panagiotis Markopoulos, Eftychia Tsironi, Pierre Ellul, Cristina Calvino Suarez, Roni Weisshof, Dana Ben-Hur, Timna Naftali, Carl Eriksson, Ioannis E. Koutroubakis, Kalliopi Foteinogiannopoulou, Jimmy K. Limdi, Eleanor Liu, Gerard Suris, Emma Calabrese, Francesca Zorzi, Rafal Filip, Davide Giuseppe Ribaldone, Yifat Snir, Idan Goren, Hagar Banai-Eran, Yelena Broytman, Hadar Amir Barak, Irit Avni-Biron, Jacob E. Ollech, Iris Dotan, Maya Aharoni Golan
Summary: This study aimed to evaluate the effectiveness of early prophylaxis with biologics in preventing endoscopic-post-operative-recurrence (ePOR) in Crohn's disease (CD) after ileocecal resection (ICR). The study compared the effectiveness of anti-tumour necrosis factor (anti-TNF) therapy with vedolizumab (VDZ) and ustekinumab (UST). The results showed that 60% of patients successfully prevented ePOR within 1 year after surgery. Patients treated with VDZ or UST were more difficult to treat. After controlling for confounders, there were no differences in ePOR risk between anti-TNF prophylaxis and other treatment groups.
JOURNAL OF CROHNS & COLITIS
(2022)
Article
Veterinary Sciences
Marco Gandini, Gessica Giusto
Summary: 7 horses underwent emergency exploratory laparotomy for acute colic caused by small intestinal obstruction, with all horses surviving to hospital discharge and most showing no subsequent signs of colic.
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
(2021)
Article
Medicine, General & Internal
Maria B. Witte, Johannes Saupe, Johannes Reiner, Karen Bannert, Clemens Schafmayer, Georg Lamprecht, Peggy Berlin
Summary: This study investigated the role of NOD2 gene after limited ileocecal resection (ICR). The results showed that Nod2 knockout mice had impaired healing after the surgery, and treatment with NOD2 agonist did not improve the situation. Additionally, Nod2 knockout mice had a lower rate of anastomotic leak.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Ilker Ozgur, Carla F. F. Justiniano, Michael A. A. Valente, Stefan D. D. Holubar, Scott R. R. Steele, Emre Gorgun
Summary: This study evaluated the management and outcomes of endoscopic treatment for ileocecal valve lesions. The results showed low complications and acceptable recurrence rates in patients treated with advanced endoscopy.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Olga Maria Nardone, Giulio Calabrese, Brigida Barberio, Mariano Cesare Giglio, Fabiana Castiglione, Gaetano Luglio, Edoardo Savarino, Subrata Ghosh, Marietta Iacucci
Summary: Kono-S ileocolic anastomosis appears to be more effective in reducing the risk of ePOR at >= 6 months compared to conventional anastomosis. However, larger randomized controlled trials are needed to confirm these findings.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Gastroenterology & Hepatology
Clara Yzet, Yann Le Baleur, Jeremie Albouys, Jeremie Jacques, Paul Doumbe-Mandengue, Maximilien Barret, Einas Abou Ali, Marion Schaefer, Jean-Baptiste Chevaux, Sarah Leblanc, Vincent Lepillez, Jocelyn Privat, Thibault Degand, Timothee Wallenhorst, Jerome Rivory, Ulriikka Chaput, Arthur Berger, Karim Aziz, Gabriel Rahmi, Emmanuel Coron, Eric Kull, Ludovic Caillo, Geoffroy Vanbiervliet, Stephane Koch, Fabien Subtil, Mathieu Pioche
Summary: This study compared the efficacy and safety of using the full thickness resection device (FTRD) system and endoscopic submucosal dissection (ESD) for the treatment of residual colorectal neoplasia (RCN). The results showed that ESD was effective in achieving R0 resection regardless of the size and location of the lesions. When residual lesions were smaller than 20 mm, FTRD was an effective alternative.
Article
Otorhinolaryngology
Roberto Saetti, Guglielmo Ronzani, Stefano Meneghesso, Marina Silvestrini
Summary: Tracheal stenosis is a rare condition where the trachea becomes narrow. A thorough preoperative evaluation is essential to determine the appropriate surgical procedure. Tracheal resection and anastomosis is a viable option, especially for extensive and high-grade lesions or failed endoscopic procedures. The patient in this case had undergone balloon dilatation and tracheal resection before, and was referred to our clinic with residual tracheal stenosis. We illustrate the surgical procedure and highlight a unique way to perform the anastomosis, particularly in a revision surgery.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Gastroenterology & Hepatology
Jordan E. Axelrad, Terry Li, Salam P. Bachour, Takahiro Nakamura, Ravi Shah, Michael C. Sachs, Shannon Chang, David P. Hudesman, Stefan D. Holubar, Amy L. Lightner, Edward L. Barnes, Benjamin L. Cohen, Florian Rieder, Eren Esen, Feza Remzi, Miguel Regueiro, Benjamin Click
Summary: Postoperative recurrence of Crohn's disease is common after ileocecal resection. This dual-center study found that early initiation of an anti-TNF agent within 4 weeks following the surgery can reduce the risk of postoperative recurrence.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Gastroenterology & Hepatology
Benjamin Click, Amit Merchea, Dorin T. Colibaseanu, Miguel Regueiro, Francis A. Farraye, Luca Stocchi
Summary: This review discusses the various surgical techniques for ileocolic resection (ICR), the common surgical procedure for Crohn's disease (CD), and examines how these techniques influence the recurrence of CD. The importance of periodic endoscopic surveillance to detect early active disease is emphasized.
INFLAMMATORY BOWEL DISEASES
(2022)
Article
Surgery
Giacomo Benassai, Carlo Serra, Gregorio Romeo, Francesca Calemma, Francesco Maione, Mariarosaria Portinaio, Marianna Scevola, Gianluca Benassai, Gennaro Quarto
Summary: In this study, a limited resection and ileocecal anastomosis method for the treatment of ileocecal valve Crohn's disease was proposed. The surgical procedure allowed the preservation of the caecum and colon, and no changes were observed in the mucosa of the ileocecal anastomosis after surgery.
ANNALI ITALIANI DI CHIRURGIA
(2022)
Article
Gastroenterology & Hepatology
Caroline Valibouze, Silvia Speca, Caroline Dubuquoy, Florian Mourey, Lena M'Ba, Lucil Schneider, Marie Titecat, Benoit Foligne, Michael Genin, Christel Neut, Philippe Zerbib, Pierre Desreumaux
Summary: In an HLA-B27 transgenic rat model, CNCM I-3856 was found to effectively prevent postoperative recurrence (POR) induced by LF82, reducing infection and gut inflammation.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
