Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons

Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments

(2015) Pabalu P. Karunadharma et al.   FASEB JOURNAL

Extensive respiratory chain defects in inhibitory interneurones in patients with mitochondrial disease

(2015) Nichola Z. Lax et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells

(2015) Karolina A. Rygiel et al.   Scientific Reports

Molecular pathogenesis of polymerase gamma-related neurodegeneration

(2014) Charalampos Tzoulis et al.   ANNALS OF NEUROLOGY

In D-loop: 40years of mitochondrial 7S DNA

(2014) Thomas J. Nicholls et al.   EXPERIMENTAL GERONTOLOGY

Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue

(2014) Anne Grünewald et al.   JOURNAL OF NEUROSCIENCE METHODS

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

(2014) Huu B. Ngo et al.   Nature Communications

Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis

(2014) Annie Hiniker et al.   Acta Neuropathologica Communications

Mitochondrial DNA Rearrangements in Health and Disease-A Comprehensive Study

(2013) Joana Damas et al.   HUMAN MUTATION

The Impact of Pathogenic Mitochondrial DNA Mutations on Substantia Nigra Neurons

(2013) A. Reeve et al.   JOURNAL OF NEUROSCIENCE

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Relationship Between Mitochondria and α-Synuclein

(2012) Amy K. Reeve   ARCHIVES OF NEUROLOGY

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Genetics of Parkinson's Disease

(2012) Kishore Kumar et al.   SEMINARS IN NEUROLOGY

Mitochondrial Pathology in Parkinson's Disease

(2011) Anthony H. V. Schapira   MOUNT SINAI JOURNAL OF MEDICINE

Structure of human mitochondrial RNA polymerase

(2011) Rieke Ringel et al.   NATURE

TFAM forces mtDNA to make a U-turn

(2011) B Martin Hallberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients

(2010) A. Rakovic et al.   HUMAN MOLECULAR GENETICS

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

(2009) Jin-Qiang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease

(2009) D. Galter et al.   GENES BRAIN AND BEHAVIOR

Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

(2009) Charles R Arthur et al.   Molecular Neurodegeneration

Resistance training in patients with single, large-scale deletions of mitochondrial DNA

(2008) J. L. Murphy et al.   BRAIN