Review
Engineering, Environmental
Paulina Wisniewska, Jozef Haponiuk, Mohammad Reza Saeb, Navid Rabiee, Sidi A. Bencherif
Summary: Metal-organic frameworks (MOFs) are a new class of crystalline porous materials comprising metal ions and organic linkers. They have high porosity and large surface area, making them attractive for various applications. However, assessing and optimizing their properties in biological systems is crucial for their clinical translation.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Jessica C. Hsu, Yu Du, Arjun Sengupta, Yuxi C. Dong, Katherine J. Mossburg, Mathilde Bouche, Andrew D. A. Maidment, Aalim M. Weljie, David P. Cormode
Summary: Comparing the clearance and cellular distribution profiles of Ag2S-NPs synthesized via different methods revealed the significant impact of ligand integrity on clearance efficiency and cellular uptake. Understanding the influence of synthetic processes on ligand integrity and subsequent nano-biointeractions is crucial for designing nanoparticle platforms with enhanced clearance and desired distribution profiles.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Medicine, Research & Experimental
Yanmei Huang, Peng Li, Ruikang Zhao, Laien Zhao, Jia Liu, Zhuhong Zhang
Summary: This article reviews the recent research progress on the biomedical applications of silica nanoparticles (SiNPs). SiNPs have great potential in drug delivery, targeted cancer treatment, and disease diagnosis due to their controllable particle size, large surface area, and good biocompatibility. However, the toxicity mechanisms of SiNPs remain poorly understood and require further investigation.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Biotechnology & Applied Microbiology
Yuyun Yang, Yuejun Liu, Laiming Song, Xiufang Cui, Juncen Zhou, Guo Jin, Aldo R. Boccaccini, Sannakaisa Virtanen
Summary: Iron-oxide-based biomagnetic nanocomposites have significant potential for biomedical applications such as MRI and cancer treatment. By modifying their properties and structure, their performance can be optimized. However, rigorous evaluation of their biosafety is needed before clinical translation.
TRENDS IN BIOTECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Simona Codruta Heghes, Oliviu Vostinaru, Cristina Mogosan, Doina Miere, Cristina Adela Iuga, Lorena Filip
Summary: Coumarins, a family of benzopyrones, are widely distributed in nature and can be found in seeds, fruits, flowers, or roots of various plant species. They are present in significant concentrations in certain herbs or spices used as nutraceuticals, but can also be found in cosmetics or household products due to their pleasant odor. Accidental exposure to high doses of coumarins can lead to harmful effects in patients. This review provides a summary of the latest published data on preclinical and clinical studies with natural coumarins, focusing on the investigation of general and specific toxicity, to better understand the safety profile of these valuable compounds. Regulatory aspects regarding the use of natural coumarins in different regions of the world are also reviewed.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Reza Abbasi, Ghazal Shineh, Mohammadmahdi Mobaraki, Sarah Doughty, Lobat Tayebi
Summary: The growing interest in using nanoparticles (NPs) for biomedical applications has raised concerns about their safety and toxicity. NPs, compared with bulk materials, are more chemically active and toxic due to their larger surface area and smaller size. Understanding the mechanism of NP toxicity and the factors affecting their behavior in biological environments can aid in the development of NPs with reduced side effects and improved performance. This review discusses the classification, properties, and biomedical applications of NPs, as well as their toxicity mechanisms and interactions with living components.
JOURNAL OF NANOPARTICLE RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Muhammad Redza Mohd Radzi, Yong Sin Yee, Mock Phooi Yan, Nur Amanina Johari, Wan Fatin Amira Wan Mohd Zawawi, Faridah Aminullah Lubis, Nur Afrina Muhamad Hendri, L. Santhana Raj, Khairunadwa Jemon
Summary: This study evaluates the subacute toxicity of modified multiwalled-carbon nanotubes (MWCNTs) and finds minimal toxicity effects, making them excellent materials for biomedical applications.
Article
Chemistry, Physical
K. Velsankar, K. Aravinth, Wang Yong, S. Mohandoss, Rok Lee Yong, Ana Claudia Paiva-Santos
Summary: The green synthesis of NiO nanoparticles using red rice grains extract was successfully achieved. The nanoparticles showed high biocompatibility, potential bio-drug activity, and good antibacterial properties. They can be used as therapeutic candidates in biomedical, clinical, and pharmaceutical fields with non-carcinogenic nature.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Review
Engineering, Biomedical
Andrew Baldwin, Brian W. Booth
Summary: Tannic Acid (TA) is a polyphenol compound with antioxidant, anti-inflammatory, antibacterial, and anticancer properties. Due to its various biochemical characteristics, it has been widely used in pharmaceutical research and biomaterials applications, showing great potential.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2022)
Article
Polymer Science
Kevin Reyes-Mateo, Oriol Careta, Jordi Hernando, Carme Nogues, Rosa Maria Sebastian
Summary: This study explores the feasibility of photothermal therapy by developing novel polybenzoxazine materials with enhanced properties. Water-soluble and nanoparticle forms of polybenzoxazine materials were prepared, and significant photothermal effects were observed upon irradiation with visible light. The effectiveness of these materials in inducing cancer cell death was demonstrated in vitro. The polybenzoxazine nanoparticle structures showed the best results, with successful cell internalization and efficient photothermal killing of cancer cells.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Pamela Floris, Stefania Garbujo, Gabriele Rolla, Marco Giustra, Lucia Salvioni, Tiziano Catelani, Miriam Colombo, Paride Mantecca, Luisa Fiandra
Summary: In this study, the toxicity of gold nanoparticles with different coating polymers on zebrafish embryos was analyzed. It was found that GNP@PEG showed significant toxicity on zebrafish embryos, while GNP@PMA exhibited mild toxicity, showing promise for the safe development of gold-based biomedical nanodevices. This raises concerns about the safety of PEGylated gold nanoparticles and contributes to the ongoing debate in the use of this nanotool in medicine and nano-biotechnologies.
Review
Biochemistry & Molecular Biology
Sagrario Yadira Gutierrez de la Rosa, Ramiro Muniz Diaz, Paola Trinidad Villalobos Gutierrez, Rita Patakfalvi, Oscar Gutierrez Coronado
Summary: Functionalized platinum nanoparticles have attracted considerable research interest as therapeutic agents due to their properties and applications. By functionalizing the nanoparticle surfaces, selectivity can be increased and the side effects of conventional drugs can be reduced. With the development of nanotechnology in the biomedical field, functionalized platinum nanoparticles have been utilized for the diagnosis and treatment of diseases such as cancer and infections. This review discusses the physical, chemical, and biological methods of obtaining platinum nanoparticles and explores the advantages and disadvantages of their synthesis. Furthermore, it explores the applications in the biomedical field that can be achieved by functionalizing the nanoparticle surfaces with different bioactive molecules, including antibodies, biodegradable polymers, and biomolecules.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Yingjie Hu, Christina Cortez-Jugo, Yi Ju, Tian Zheng, Jiajing Zhou, Zhixing Lin, Robert De Rose, Christoph E. Hagemeyer, Karen Alt, Frank Caruso
Summary: This study investigated the impact of nanoparticle cross-linking on liver uptake. The findings indicate that the cross-linking structure of nanoparticle can modulate the targeting ability of antibody nanoparticles in model cell lines and their interaction with phagocytes in human blood. The molecular architecture of PEG can also increase the tumor accumulation of antibody nanoparticles by reducing their uptake in the liver.
CHEMISTRY OF MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Saman Sargazi, Mohammad Reza Hajinezhad, Abbas Rahdar, Mahwash Mukhtar, Milad Karamzadeh-Jahromi, Mohammad Almasi-Kashi, Sima Alikhanzadeh-Arani, Mahmood Barani, Francesco Baino
Summary: Nanoparticles of CoNi alloy were successfully synthesized and tested for their cytotoxic effects on cancer cells and in vivo on rats, showing significant toxicity towards breast cancer and oral cavity cancer cells, as well as biochemical and histopathological changes in the rats.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2021)
Article
Biochemistry & Molecular Biology
Irena Maliszewska
Summary: This paper describes the synthesis of colloidal gold nanoparticles using cell-free filtrate from Coriolus versicolor biomass, and the enhancement of photodynamic therapy efficiency using these nanostructures. The obtained gold nanoparticles were stable and characterized by a spherical shape with a single plasmon band. The study showed that the combination of gold nanoparticles with hydroxyaluminum phthalocyanines effectively killed Staphylococcus aureus in antibacterial photodynamic therapy.
Article
Environmental Sciences
Muqiu Hu, Xin Zhao, Jinghan Gu, Lulu Qian, Zhiqing Wang, Yuanyuan Nie, Xiaoyu Han, Long An, Haiqiang Jiang
Summary: Due to its simple process, environmental friendliness, and low operating costs, biometallurgy has become a popular technology for metals recovering from low-grade ores and tailings. An optimized agar was used to isolate and grow functional bacteria, resulting in the successful isolation of six functional stains. These strains were further tested for their ability to leach metals from polymetallic sulfide tailings, with significant improvements observed when the strains were mixed together. The selection of leaching process should be based on tailings composition and target metals.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Saqib Hassan, Aswin Thacharodi, Anshu Priya, R. Meenatchi, Thanushree A. Hegde, R. Thangamani, Ht Nguyen, Arivalagan Pugazhendhi
Summary: An Endocrine Disrupting Chemical (EDC) is a compound that disrupts the function of the endocrine system and is found in the environment. EDCs, such as Bisphenol A and pesticides, have been shown to have negative effects on the female reproductive system. Understanding the relationship between EDCs and women's health is crucial for developing strategies to protect reproductive health and informing public policy decisions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Lichang Zhou, Zhaoling Li, Boyi Cheng, Jinqi Jiang, Xinqi Bi, Zongping Wang, Guanghao Chen, Gang Guo
Summary: Thiosulfate can promote sulfur-mediated bacterial activity, inhibit glycogen accumulating organisms, and enhance denitrification efficiency. After the carbon source is reduced, the competitive ability of glycogen accumulating organisms increases, resulting in reduced sulfate reduction.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Claire E. Campbell, Devyn L. Cotter, Katherine L. Bottenhorn, Elisabeth Burnor, Hedyeh Ahmadi, W. James Gauderman, Carlos Cardenas-Iniguez, Daniel Hackman, Rob McConnell, Kiros Berhane, Joel Schwartz, Jiu-Chiuan Chen, Megan M. Herting
Summary: Recent studies have found a connection between air pollution and increased risk for behavioral problems during development. However, more longitudinal studies are needed to investigate how exposure during the transition to adolescence may affect emotional behaviors.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Jing-hong Liang, Ru-yu Yang, Mei-ling Liu, Ying-qi Pu, Wen-wen Bao, Yu Zhao, Li-xin Hu, Yu-shan Zhang, Shan Huang, Nan Jiang, Xue-ya Pu, Shao-yi Huang, Guang-hui Dong, Ya-jun Chen
Summary: This study examines the association between urban Green and blue spaces (GBS) exposure and Emotion and behavior problems (EBP) in youth populations. The findings suggest that higher exposure to GBS, particularly green spaces (GS) and blue spaces (BS), is associated with a decrease in the risk of developing total difficulties in young individuals. The joint effect of GS and BS may also contribute to the decrease in EBPs.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Diego Ruiz-Sobremazas, Mario Ruiz Coca, Miguel Morales-Navas, Rocio Rodulfo-Cardenas, Caridad Lopez-Granero, Maria Teresa Colomina, Cristian Perez-Fernandez, Fernando Sanchez-Santed
Summary: Air pollution is associated with a range of health issues and gestational exposure to environmental pollutants may be linked to neurodevelopmental disorders. This study investigated the effects of oral gestational exposure to particulate matter (PM) on ultrasonic vocalizations (USV). The findings suggest that this exposure may lead to social deficits and abnormal gene expression related to neurotransmitter systems. Further research is needed to better understand the effects of air pollution on neurodevelopmental disorders and the neurotransmission systems involved.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yagmur Kabakci, Sadiye Kosar, Ozgur Dogan, Fehmi Gorkem Uctug, Osman Atilla Arikan
Summary: This study investigated the effect of electrohydrolysis pretreatment on municipal solid waste. The results showed that applying electrohydrolysis pretreatment increased methane production and reduced the time required for hydrolysis, suggesting it is a promising method to improve anaerobic digestion efficiency.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Chuanwu Zhao, Yaozhong Pan, Hanyi Wu, Yu Zhu
Summary: This study analyzed the impact of industrial zones on urban heat islands using remote sensing images and a novel spectral index. The research found that the contraction or expansion of industrial zones has a significant effect on land surface temperature. The results are valuable for environmental assessment and fine management of industrial cities.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Bang Du, Zhongzhong Wang, Piet N. L. Lens, Xinmin Zhan, Guangxue Wu
Summary: This study investigated the performance, syntrophic relationships, microbial communities, and metabolic pathways of ethanol-fed reactors with different operational modes and solids retention times. The results showed that different microorganisms were enriched under different SRT conditions, and syntrophic bacteria related to methane production could be enriched under low SRT conditions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Gokulan Ravindiran, Sivarethinamohan Rajamanickam, Muralikrishnan Ramalingam, Gasim Hayder, Balamurugan Karupaiya Sathaiah, Madhava Krishna Reddy Gaddam, Senthil Kumar Muniasamy, Priya Arunkumar
Summary: The present study investigated the sustainable approach for wastewater treatment using waste algal blooms. The biochar produced by the marine algae Ulva reticulata was used to remove chromium, nickel, and zinc from aqueous solutions. The study examined the adsorbents' properties and stability using SEM/EDX, FTIR, and XRD. The results showed that the biochar had high removal efficiency for the toxic metals, and the packed bed column effectively removed the heavy metal ions. The Thomas and Adams-Bohart models were found to best fit the regression values, and desorption studies were conducted to understand the sorption and elution processes.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Vignesh Vinayagam, Kavitha Nagarasampatti Palani, Sudha Ganesh, Siddharth Rajesh, Vedha Varshini Akula, Ramapriyan Avoodaiappan, Omkar Singh Kushwaha, Arivalagan Pugazhendhi
Summary: The presence of pollutants in water contributes to global pollution and poses significant threats to humans and wildlife. Finding effective wastewater treatment techniques is crucial for reducing pollutant accumulation in the environment. This paper highlights recent advances in the electrochemical advanced oxidation method and other processes for treating pharmaceuticals, dyes, and pesticide-polluted effluents.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
M. M. M. Ahmed, Kai-Yue Chen, Fang-Yu Tsao, Yi-Cheng Hsieh, Yu-Ting Liu, Min Tzou
Summary: This study investigated the sorption of citric acid onto humic acid-iron hydr(o)xide coprecipitate (HAFHCP) and the reciprocal effects of citric acid and P sorption on HAFHCP. The results showed that citric acid could increase P availability and have an impact on P sorption.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Xibo Xu, Zeqiang Wang, Xiaoning Song, Wenjie Zhan, Shuting Yang
Summary: The selection of predictor variables is crucial in building a digital mapping model for potentially toxic elements (PTEs) in soil. Traditionally, spatial and spectral parameters have been used as predictor variables, but the temporal dimension is often overlooked. This study demonstrates the value of incorporating temporal indices in the model, leading to significant performance improvements. The temporal-spatial-spectral covariate combinations used in a random forest (RF) algorithm achieve satisfactory mapping accuracy and outperform other methods.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yan Pei, Xun Liu, Mengbo Cao, Zijun Wang, Hongbing Yang
Summary: Heteroatom doping can reconfigure the electronic structure of heterogeneous catalysts, leading to the development of advanced oxidation water purification materials with superior performance and stability. In this study, a series of catalysts with different elemental doping were prepared using a simple and environmentally friendly method. The S-doped NiCo2O4 catalyst showed excellent catalytic performance for the removal of Tetracycline, with significantly increased kinetic constant and high oxidation and mineralization efficiency in a wide pH range. The degradation process was dominated by non-radical oxidation pathway after S doping, and the overall process moved towards low toxicity.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Srivalli Thimmarayan, Harshavardhan Mohan, Gaddapara Manasa, Karthi Natesan, Shanmugam Mahendran, Pavithra Muthukumar Sathya, Byung-Taek Oh, R. Ravi Kumar, Rangasamy Sigamani Gandhimathi, Arul Jayaprakash, Kamala-Kannan Seralathan
Summary: This study investigated the bacterial degradation of naphthalene (NPT) isolated from crude oil-contaminated soil. Bacillus sp. GN 3.4, a potential bacteria for NPT biodegradation, was isolated and the optimal conditions for NPT degradation were determined. The study suggests that Bacillus sp. GN 3.4 could potentially aid in bioremediation by eliminating NPT from the soil.
ENVIRONMENTAL RESEARCH
(2024)