期刊
CURRENT ORGANIC CHEMISTRY
卷 23, 期 6, 页码 704-720出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272823666190404163748
关键词
Chinese herbal medicine; natural product; aqueous two-phase system; application; extraction; amplify
资金
- National Natural Science Foundation of China [21476090]
- Science and Technology Planning Project of Guangdong Province, China [2017A010104005]
- Fundamental Research Funds for the central Universities
Background: In the past decades, Chinese herbal medicine has attracted worldwide attention because they contain a variety of active ingredients which are beneficial to human health. As a result, there is a growing interest in the extraction of these substances. However, traditional extraction methods not only need a large amount of extractant, but arc also time-consuming, moreover, the extraction efficiency is extremely poor and tedious purification steps are required to purify the crude extract. Thus, researchers hope to fund an alternative method for the extraction of these components and the aqueous two-phase system (ATPS) seems to be one. Objective: This review focuses on introducing the properties of the aqueous two-phase system and summarizing the application of ATPS in the extraction of natural products. Meanwhile, this review also provided a guideline to researchers who wish to design a suitable ATPS for a specific target and how to amplify it to industrial-scale.
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