Review
Biochemistry & Molecular Biology
Evelyn Kabirova, Artem Nurislamov, Artem Shadskiy, Alexander Smirnov, Andrey Popov, Pavel Salnikov, Nariman Battulin, Veniamin Fishman
Summary: This review summarizes the essential role of SMC complexes in chromatin biology, including mitotic chromosome formation and sister chromatid cohesion, as well as their involvement in gene regulation, DNA repair, and chromatin topology. The article provides an overview of the anatomy of SMC complexes and their accessory proteins, as well as biochemical details of the extrusion process.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Frank Burmann, Jan Lowe
Summary: Structural maintenance of chromosomes (SMC) complexes safeguard and organize the three-dimensional structure of chromosomal DNA. They possess motor activity that extrudes large DNA loops as they move along their substrate, explaining many SMC functions. This review focuses on recent structural insights into the architecture and conservation of these molecular machines, their interaction with DNA, and the conformational changes associated with their ATP hydrolysis cycle.
CURRENT OPINION IN STRUCTURAL BIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Eugene Kim, Roman Barth, Cees Dekker
Summary: SMC (structural maintenance of chromosomes) protein complexes are motor proteins that hold sister chromatids together and fold genomes throughout the cell cycle. They play important roles in chromosome packaging and regulation, but the molecular mechanism for DNA loop extrusion by SMC complexes is still unresolved. This review focuses on the roles of SMCs in chromosome biology and discusses recent in vitro single-molecule studies that have advanced our understanding of SMC proteins and the mechanistic aspects of loop extrusion.
ANNUAL REVIEW OF BIOCHEMISTRY
(2023)
Article
Computer Science, Information Systems
Suhyeon Kim, Hyeongjun Cho, Dongwon Jung
Summary: This paper presents a guidance algorithm for the circular formation flight of multiple fixed-wing UAVs. The algorithm aims at reducing both the radial and the phase angle error with respect to a moving reference point located at a fixed distance from the leader UAV. The proposed control law is compared with an existing vector-field formation guidance scheme through numerical simulation. Extensive validation and flight tests demonstrate the performance and robustness of the proposed algorithm, including its capability to handle wind disturbance.
Article
Automation & Control Systems
Ximan Wang, Simone Baldi, Xuewei Feng, Changwei Wu, Hongwei Xie, Bart De Schutter
Summary: The paper proposes a non-uniform vector field method for UAV formation control, which does not assume the absence of wind. The stability of the method is analyzed using Lyapunov stability theory and validated through comparative experiments.
IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING
(2023)
Article
Engineering, Mechanical
Olga A. Zadubrovskaya, Dmitry A. Gavrilov, Grigory Nesterov, Pavel Poshibaev
Summary: This study evaluates the endurance of cold bending elbows made of K56 strength class steel using low-cycle fatigue tests. The results show that the endurance of the bent part of elbows in the stretched and compressed zones is not lesser than that of the unstrained zone. The study also defines the relationship between the relative reduction of the tested specimens and the quantity of loading cycles.
NAUKA I TEHNOLOGII TRUBOPROVODNOGO TRANSPORTA NEFTI I NEFTEPRODUKTOV-SCIENCE & TECHNOLOGIES-OIL AND OIL PRODUCTS PIPELINE TRANSPORTATION
(2022)
Article
Energy & Fuels
Tiantian Shi, Wenbo Liu, Zhengxiong Su, Xu Yan, Chenyang Lu, Zhaoxi Yang, Xinfu He, Wei Yan, Di Yun
Summary: The experimental results showed that bubbles in the Fe-9Cr alloy have different spatial distributions along the depth. In regions with higher helium concentration and irradiation doses, bubbles tend to form bubble-loop complexes. However, in regions with lower helium concentration and doses, the number of bubble-loop complexes decreases significantly. The enrichment of Cr atoms at the bubble-loop complexes was quantitatively estimated using energy-dispersive X-ray spectroscopy in scanning TEM mode.
FRONTIERS IN ENERGY RESEARCH
(2021)
Article
Orthopedics
Samuel Bachmaier, Patrick A. Smith, Sommer Hammoud, Daniel Ritter, Oliver Hauck, Coen A. Wijdicks
Summary: This study investigates the biomechanical performance of a new knotless adjustable anterior cruciate ligament (ACL) repair system compared to a fixed repair system. The results show that the knotless adjustable repair system provides higher construct stability, greater load share on the ACL at lower loads, and reduced gap formation.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Agnes Grenacs, Nikolett Bodnar, Dora Csilla Palinkas, Norbert Lihi, Katalin Varnagy
Summary: The thermodynamic stability and structure of nickel(ii), zinc(ii), and cadmium(ii) complexes with cysteine-containing ligands were studied. Different ligands were shown to affect the coordination properties of the metal ions.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Yan Li, Judith H. I. Haarhuis, Angela Sedeno Cacciatore, Roel Oldenkamp, Marjon S. van Ruiten, Laureen Willems, Hans Teunissen, Kyle W. Muir, Elzo de Wit, Benjamin D. Rowland, Daniel Panne
Article
Multidisciplinary Sciences
Claire Hoencamp, Olga Dudchenko, Ahmed M. O. Elbatsh, Sumitabha Brahmachari, Jonne A. Raaijmakers, Tom van Schaik, Angela Sedeno Cacciatore, Vinicius G. Contessoto, Roy G. H. P. van Heesbeen, Bram van den Broek, Aditya N. Mhaskar, Hans Teunissen, Brian Glenn St Hilaire, David Weisz, Arina D. Omer, Melanie Pham, Zane Colaric, Zhenzhen Yang, Suhas S. P. Rao, Namita Mitra, Christopher Lui, Weijie Yao, Ruqayya Khan, Leonid L. Moroz, Andrea Kohn, Judy St Leger, Alexandria Mena, Karen Holcroft, Maria Cristina Gambetta, Fabian Lim, Emma Farley, Nils Stein, Alexander Haddad, Daniel Chauss, Ayse Sena Mutlu, Meng C. Wang, Neil D. Young, Evin Hildebrandt, Hans H. Cheng, Christopher J. Knight, Theresa L. U. Burnham, Kevin A. Hovel, Andrew J. Beel, Pierre-Jean Mattei, Roger D. Kornberg, Wesley C. Warren, Gregory Cary, Jose Luis Gomez-Skarmeta, Veronica Hinman, Kerstin Lindblad-Toh, Federica Di Palma, Kazuhiro Maeshima, Asha S. Multani, Sen Pathak, Liesl Nel-Themaat, Richard R. Behringer, Parwinder Kaur, Rene H. Medema, Bas van Steensel, Elzo de Wit, Jose N. Onuchic, Michele Di Pierro, Erez Lieberman Aiden, Benjamin D. Rowland
Summary: The study identified two types of three-dimensional genome architectures at the chromosome scale in eukaryotes, with one type correlated with the absence of condensin II subunits. Depletion of condensin II in humans results in a genome structure resembling that of fungi or mosquitoes. The research proposes a physical model in which condensin II compacts chromosomes lengthwise during mitosis, influencing the chromosome-scale genome architecture.
Article
Biochemistry & Molecular Biology
Marjon S. van Ruiten, Demi van Gent, Angela Sedeno Cacciatore, Astrid Fauster, Laureen Willems, Maarten L. Hekkelman, Liesbeth Hoekman, Maarten Altelaar, Judith H. I. Haarhuis, Thijn R. Brummelkamp, Elzo de Wit, Benjamin D. Rowland
Summary: The acetylation of cohesin's SMC3 subunit controls the three-dimensional genome structure in human cells. ESCO1 restricts the length of chromatin loops and architectural stripes, while HDAC8 promotes their extension. Acetylation also controls the interaction of cohesin with PDS5A to limit chromatin loop length.
NATURE STRUCTURAL & MOLECULAR BIOLOGY
(2022)
