期刊
COMPOSITES PART B-ENGINEERING
卷 162, 期 -, 页码 154-161出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.compositesb.2018.10.094
关键词
Public health; Ti scaffolds; Selective laser melting; The bionic pores; Bone tissue engineering
资金
- National Key Research and Development Program of China [2018YFB1105600, 2018YFC1106800]
- Key R&D project of Sichuan Province [2018GZ0142]
- Sichuan Province Major Scientific & Technological Achievements Transformation Demonstration Project [2016CZYD0004]
- Sichuan Province Science & Technology Department Key Projects [2017SZ0001]
- 111 Project [B16033]
Bone defect and osteoporosis are common in clinic which are seriously harmful for public health. Bionic bone tissue engineering scaffolds are very important for bone tissue repair and reconstruction. In this study, different bionic bone tissue engineering scaffolds were constructed by computer-aided design and fabricated by selected laser melting. Novel porous structures were designed by using parameterization modeling. The accurate models with key characteristics such as porosity and the mechanical property of scaffolds were studied. Compared with the designed model, the error of the selective laser melting (SLM) printed scaffold porosity was less than 2.73%. The mechanical properties of the prepared scaffold can be calculated by finite element analysis of 3D models, and the mechanical properties of the 3D printed samples were consistent with the model design. Through the design, manufacture, characterization and evaluation of the scaffold porous structures, the parametric modeling of porous titanium bone tissue engineering scaffold with good mechanical and biological properties was realized. Optimized design and precisely manufactured implants are very important for bone tissue repair and reconstruction.
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