Article
Chemistry, Applied
Saranya Sundar, Ramesh Rengan, Anandaraj Pennamuthiriyan, David Semeril
Summary: A facile catalytic one-pot synthesis of N-acylhydrazones has been described using arene ruthenium (II) complexes. The method provides a wide range of N-acylhydrazones in good yields with high selectivity and functional group tolerance, without any alkylated products.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Shivangi Gupta, Ankur Maji, Dibyajyoti Panja, Mita Halder, Sabuj Kundu
Summary: Efficient synthesis of quinolines, pyridines, and pyrroles via alcohol dehydrogenative coupling strategy using copper oxide nanoparticles as catalyst is reported. Various functionalized quinolines, pyridines, and pyrroles were efficiently synthesized from different amino alcohols and a diverse range of ketones. Control experiments were conducted to elucidate the mechanism. The catalyst showed no significant loss in catalytic activity after being recycled up to 6 runs.
JOURNAL OF CATALYSIS
(2022)
Review
Chemistry, Organic
Pinaki Nad, Arup Mukherjee
Summary: Acceptorless dehydrogenative coupling reactions using manganese catalyst is a promising and sustainable method for constructing carbon-carbon and carbon-heteroatom bonds. The methodology is highly atom economical, producing water and hydrogen as byproducts, and provides a unique opportunity for constructing various synthons and biologically important motifs. Recent progress in this field has been made with manganese catalysis based on pincer ligands for various homogeneous transformations.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Zhijun Li, Xiaowen Lu, Rufang Zhao, Siqi Ji, Mingyang Zhang, J. Hugh Horton, Yang Wang, Qian Xu, Junfa Zhu
Summary: Researchers have developed an efficient molten-salt-assisted approach to create atomically dispersed cobalt atoms supported over vanadium pentoxide layered material. This cobalt single-atom catalyst achieves extraordinary catalytic efficiency in the dehydrogenative coupling reaction of alcohols and amines, with high selectivity and conversion. Density functional theory calculations confirm the optimized coordination environment and strong metal-support interaction contribute significantly to the activation of reactants.
Article
Chemistry, Inorganic & Nuclear
Aswathi N. E. Ravindran, Dharmalingam Sindhuja, Nattamai Bhuvanesh, Ramasamy Karvembu
Summary: The catalytic activity of Ru(II)-arene complexes containing ferrocene thiosemicarbazone (Fc-TSC) ligands towards the selective synthesis of 1,2-disubstituted benzimidazoles via acceptorless dehydrogenative coupling of diamines with primary alcohols was investigated. The electronic effect of ligands on the catalytic activity of their complexes was studied, leading to the conclusion of achieving good to moderate yields in the synthesis of 1,2-disubstituted benzimidazoles.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Aswathi Ravindran, Maheepal Yadav, Manoharan Muthu Tamizh, Nattamai Bhuvanesh, Sunandan Sarkar, Ramasamy Karvembu
Summary: A series of Ru(II)-p-cymene complexes based on ferrocene-hydrazone were investigated for their catalytic activity in acceptorless dehydrogenative coupling (ADC) reactions. The Ru(II)-p-cymene isonicotinic Fc-hyrazone complex showed better performance in the solvent-free synthesis of 1,2-disubstituted benzimidazoles (up to 88%) and quinazolinones (up to 95%). The catalytic experiments demonstrated good to moderate yields, with hydrogen and water as the only by-products.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Xiangchao Xu, Yao Ai, Rongzhou Wang, Liping Liu, Jiazhi Yang, Feng Li
Summary: A ruthenium complex with a functional ligand was synthesized and found to be an efficient catalyst for the synthesis of quinolines. The NH units in the ligand were crucial for the catalytic activity. This research demonstrates the potential of metal-ligand bifunctional catalysts for acceptorless dehydrogenative reactions.
JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Physical
Shuaicong Huo, Siqi Kong, Guang Zeng, Qi Feng, Zhiqiang Hao, Zhangang Han, Jin Lin, Guo-Liang Lu
Summary: Treatment of N,N,O-tridentate pyrazolyl-pyridinyl-alcohol ligands with RuCl3.xH(2)O in refluxing EtOH afforded Ru(III) complexes, which showed high catalytic performance for dehydrogenative couplings of 2-aminoarylmethanols with ketones and nitriles, providing a sustainable route to access various structurally important quinoline and quinazoline derivatives.
MOLECULAR CATALYSIS
(2021)
Article
Chemistry, Organic
Swadhin Chetia, Samprity Sarmah, Apurba Dutta, Diganta Sarma
Summary: A copper acetate monohydrate catalyzed protocol for the construction of quinazoline derivatives and quinolines analogues via dehydrogenative coupling of 2-aminoaryl methanols and nitriles is developed. The reaction proceeded in toluene at 110 degrees C for 5 h without the requirement of inert condition, external additives, and ligands.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Tamilthendral Veerappan, Ramesh Rengan
Summary: A sustainable synthesis of substituted pyrazoles is achieved via an eco-friendly dehydrogenative annulation reaction using newly synthesized binuclear Ru-(II) p-cymene complexes. The reaction proceeds under mild conditions, producing H(2)O/H-2 as the only byproduct, and yields a range of polysubstituted pyrazoles and a therapeutic gout medicine analogue successfully.
Article
Chemistry, Organic
Delia Bellezza, Ramon J. Zaragoza, M. Jose Aurell, Rafael Ballesteros, Rafael Ballesteros-Garrido
Summary: The use of diols and anilines as reagents for indole synthesis is a challenging task in organic chemistry. Through the acceptorless dehydrogenative condensation method, heterocycles like indoles can be efficiently obtained. This study successfully reduced the excess of diols to 2 equivalents using heterogeneous catalysts, and explored pathways for the synthesis of various indole-like compounds.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Organic
Ling Zhao, Xiaochun He, Tianhua Cui, Xufeng Nie, Jiaqi Xu, Xueli Zheng, Weidong Jiang, Maolin Yuan, Hua Chen, Haiyan Fu, Ruixiang Li
Summary: The acceptorless dehydrogenative cross-coupling of primary alcohols to form cross-esters with the liberation of H2 gas was achieved using a [RuCl(eta 6-C6H6)(Kappa 2-CNP)][PF6]Cl complex as the catalyst. This sustainable protocol is applicable to a wide range of primary alcohols, particularly those that are sterically demanding, and it exhibits good functional group tolerance and high selectivity. The nitrogen-phosphine-functionalized N-heterocyclic carbene (CNP) ligand, which adopts a facial coordination mode and allows for facile dissociation of coordinated benzene, is responsible for the excellent catalytic performance.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Review
Chemistry, Organic
Bivas Chandra Roy, Kasturi Ganguli, Sk. Abdus Samim, Sabuj Kundu
Summary: Alcohol has garnered special attention in the past two decades due to its abundance, low cost, and low toxicity, making it a versatile building block for synthesizing value-added products. Metal-ligand cooperation is a powerful tool for utilizing alcohol in the synthesis of complex molecules. This review focuses on stable metal-ligand cooperative 5d, 4d, and 3d metal-based complexes for effective alcohol dehydrogenative coupling reactions.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Xiaona Yang, Yunfei Guo, Hong'en Tong, Rongfang Liu, Rong Zhou
Summary: In this work, a metal-free acceptorless dehydrogenative cross-coupling reaction for both carbon-heteroatom and carbon-carbon bond formation has been developed. The reaction was achieved through the synergistic catalysis of the organophotocatalyst 4CzIPN and a thiol under blue light irradiation, enabling the coupling of aldehydes with alcohols or two different alcohols with a broad substrate scope and good functional group compatibility. Mechanistic studies revealed the generation and subsequent oxidation of an acyl radical to its cation under photocatalytic conditions.
Article
Chemistry, Organic
Nandita Biswas, Dipankar Srimani
Summary: The Ru-catalyzed reaction provides an economical and simple operational strategy for synthesizing biologically active 1,8-dioxodecahydroacridine derivatives with a wide substrate scope and good tolerance toward various functional groups.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Engineering, Environmental
Wei Zhang, Cong Li, Jun-Yang Ji, Zheng Niu, Hongwei Gu, Brendan F. Abrahams, Jian-Ping Lang
Summary: In this study, a Co/CoO/CoN heterostructure catalyst dispersed in hierarchical porous N-doped graphitic carbon on carbon cloth was prepared using a facile method. The active centers in the catalytic process were investigated by DFT calculations. Due to the strong interaction and electronic structure reconfiguration between interfaces, the optimized catalyst, Co/CoO/CoN/CC-2, exhibited remarkable catalytic activity for both HER and OER.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Inorganic & Nuclear
Min-Jie Zhang, Yu Ge, Chen Cao, Xin-Ran Xue, Qiu-Yi Li, Qi Liu, Jian-Ping Lang
Summary: A flexible metal-organic framework (MOF), {[Cd(1,4-bdc)(4-bpa)]center dot DMF}n (1), was prepared and used to synthesize and store pure interhalogens. The embedded interhalogen molecules were stabilized by interactions with the inner groups of the porous framework and released for organic reactions. This work provides a new approach for the synthesis of pure interhalogens and demonstrates the potential applications of MOF crystal vessels in reactions.
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
(2023)
Article
Chemistry, Medicinal
Mengyao Feng, Fuyuan Liu, Ningwen Yang, Jiayao Yu, Wei Yang, David James Young, Xiang-Qian Cao, Hong-Xi Li, Zhi-Gang Ren
Summary: A heterobimetallic coordination polymer [Au4(dppmt)4(AgCl)2]n (1) incorporating an in situ generated P-S ligand (dppmtH) was synthesized. The structure of 1 contains a one-dimensional helical Au-Au chain. Coordination polymer 1 exhibited a rapid, selective, reversible, and visible vapor chromic response on exposure to methanol (MeOH) vapor.
ACS MEDICINAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Mengling Zhang, Yu Ge, Zheng Qin, Qilei Jiang, Xianggang Huang, Yan Hou, Yingxin Liu, Xueqin Cao, Jian-Ping Lang, Hongwei Gu
Summary: This study demonstrates reversible single-crystal-to-single-crystal (SCSC) transformations between nanoscale three-dimensional ZIF-67 and two-dimensional Co-LDH. The resulting Co-LDH materials show superior oxygen evolution reaction performance, indicating their potential value in crystal synthesis and resource recycling.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yu-Xuan Hong, Meng-Fan Wang, Yu Ge, Hong Yu, Chun-Yan Ni, Wei-Yi Chen, Pierre Braunstein, Jian-Ping Lang
Summary: The solid-state [2 + 2] photocycloaddition experiment introduced in this study provides senior undergraduate students with a comprehensive understanding of coordination chemistry, organic chemistry, structural chemistry, and supramolecular chemistry. This experiment not only strengthens students' experimental skills, but also broadens their research horizon and promotes rigorous thinking in a laboratory course.
JOURNAL OF CHEMICAL EDUCATION
(2023)
Article
Chemistry, Multidisciplinary
Ze-Ming Xu, Zhuoyi Hu, Yali Huang, Shu-Jin Bao, Zheng Niu, Jian-Ping Lang, Abdullah M. Al-Enizi, Ayman Nafady, Shengqian Ma
Summary: Hydrogenated nitrogen heterocyclic compounds are critical in various industries. Previous studies on the partial hydrogenation of these compounds have focused on costly and toxic precious metal catalysts. This research introduces a novel P/B type MOF-FLP catalyst achieved through a solvent-assisted linker incorporation approach, which significantly enhances catalytic hydrogenation reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Jia-Jun Yan, Yu Wu, Weijia Zhai, Ningwen Yang, Hong-Xi Li, Wei Yang, Chengrong Lu, David James Young, Zhi-Gang Ren
Summary: The reaction of CF3COOAg, 3-bdppmapy and HTZ in CH2Cl2/MeOH resulted in a dinuclear Ag/P/S complex [Ag-2(TZ)(2)(3-bdppmapy)(2)]& BULL;xSol (1 & BULL;xSol). Crystals of 1 & BULL;xSol converted to 1 & BULL;2MeOH in air at room temperature and further to 1 under vacuum upon heating. The solid-state, room-temperature photoluminescent emission of 1 & BULL;xSol (510 nm) shifted to 494 nm (1 & BULL;2MeOH) and 486 nm (1).
Article
Chemistry, Organic
Da-Liang Zhu, Jie Li, David James Young, Yanqing Wang, Hong-Xi Li
Summary: This paper presents a mild strategy for aminating aryl halides with anilines using dual photoredox and nickel catalysis. Thioxanthen-9-one, an inexpensive and readily available compound, greatly enhanced this cross-coupling reaction, yielding a diverse range of diarylamines in good yields (41-93%) at room temperature. The reaction could be performed under compact fluorescent lamp light or sunlight and was tolerant of various functional groups. It was successfully applied to the synthesis of natural products and drug molecules, even at a gram-scale. The mechanism involves several steps including oxidative addition, transmetalation, energy transfer, and reductive elimination.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Shengnan Hu, Sisi Yan, Yuanyuan Hu, David James Young, Hong-Xi Li, Chengrong Lu, Jing-Hui He, Zhi-Gang Ren
Summary: Reliable and sensitive detection of sub-ppm level, ultra-low humidity is critical for a number of important technologies. We report a heteronuclear Au2Cu2 cluster complex that can undergo reversible transformations and has photoluminescent properties in different environments. The crystals of the complex can detect ultralow humidity of 0.21 ppm (w/w).
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Inorganic & Nuclear
You-Hui Zhao, Hai-Yan Li, David James Young, Xiangqian Cao, Da-Liang Zhu, Zhi-Gang Ren, Hong-Xi Li
Summary: Earth-abundant copper(I) coordination complexes have been developed as visible-light photocatalysts for the intermolecular atom-transfer radical addition reactions. Four heteroleptic bis-chelate Cu(I) complexes were synthesized and showed broad absorption in the visible spectrum. These complexes facilitated efficient reactions with CBr4, CCl3Br, and CHI3, yielding high product yields up to 91%. The substitution on the phpz ligand had a significant impact on the absorption, emission, redox potential, and photocatalytic activity.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Mengyao Feng, Fuyuan Liu, Ningwen Yang, Jiayao Yu, Wei Yang, David James Young, Xiang-Qian Cao, Hong -Xi Li, Zhi-Gang Ren
Summary: A heterobimetallic coordination polymer [Au-4(dppmt)(4)(AgCl)2(]) n (1) with an in situ generated P-S ligand (dppmtH) was synthesized. The structure of 1 contains a helical Au-Au chain connected by [Au(2()dppmt)(2)] dimers. Upon excitation at 343 nm, 1 exhibited cyan phosphorescent emission at QY = 22.3% and t = 0.78 μs. Coordination polymer 1 exhibited a rapid, selective, reversible, and visible vaporchromic response on exposure to methanol vapor, with its emission shifting to a more intense green at QY = 46.8% and t = 1.24 μs.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Zhi-Hao Zhang, Jia-Lu Ge, Yan Li, Qing Li, Pin-Pin Ma, Xiao-Yan Tang, Wen-Hua Zhang, David J. Young
Summary: Developing porous materials for efficient capture of I-2 is important for the sequestration and storage of radioactive iodine towards clean nuclear energy. In this study, three structurally identical two-dimensional (2D) metal-organic frameworks (MOFs) were prepared, and one of the MOFs showed the highest adsorption capacity for I-2.
Article
Chemistry, Physical
Weichan Zhong, Dixing Chen, Yuting Wu, Jingxiu Yue, Zhangfeng Shen, Hong Huang, Yangang Wang, Xi Li, Jian-Ping Lang, Qineng Xia, Yongyong Cao
Summary: This study proposes a systematic approach to screen efficient double-atom catalysts (DACs) for urea production, using nitrogen and carbon dioxide as precursors, with the help of density functional theory (DFT). The results show that co-doped graphdiyne with CrB and MnB double atoms emerge as potential electrocatalysts for urea production, displaying low energy barriers and the capability to suppress the formation of unwanted by-products. The study establishes a theoretical framework for the evaluation of DACs in electrocatalytic urea synthesis.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Biochemistry & Molecular Biology
Shan He, Yixiao Wu, Yang Zhang, Xuan Luo, Christopher T. Gibson d Jingrong Gao, Jingrong Gao, Matt Jellicoe, Hao Wang, David J. Young, Colin L. Raston
Summary: Biodegradable cellulose films derived from kombucha, processed using a vortex fluidic device, show increased mechanical strength due to intense micromixing and high shear stress of the liquid film. The films retain their biodegradability and degrade within 5 days.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
