期刊
ANNALS OF BIOMEDICAL ENGINEERING
卷 44, 期 6, 页码 1946-1958出版社
SPRINGER
DOI: 10.1007/s10439-016-1637-z
关键词
Hydrogel; Microgel; Microparticle; Protein delivery; Growth factor; PEG; PNIPAM
资金
- NIH [R01 AR062368, R01 AR062920, R21 EB020107, T32 EB006343]
- Juvenile Diabetes Research Foundation [2-SRA-2014-287-Q-R, 3-SRA-2015-38-Q-R]
Proteins represent a major class of therapeutic molecules with vast potential for the treatment of acute and chronic diseases and regenerative medicine applications. Hydrogels have long been investigated for their potential in carrying and delivering proteins. As compared to bulk hydrogels, hydrogel microparticles (microgels) hold promise in improving aspects of delivery owing to their less traumatic route of entry into the body and improved versatility. This review discusses common methods of fabricating microgels, including emulsion polymerization, microfluidic techniques, and lithographic techniques. Microgels synthesized from both natural and synthetic polymers are discussed, as are a series of microgels fashioned from environment-responsive materials.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据