Potential Roles of NIX/BNIP3L Pathway in Rat Traumatic Brain Injury

NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury

(2018) Kebin Xu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Intranasally Delivered Wnt3a Improves Functional Recovery after Traumatic Brain Injury by Modulating Autophagic, Apoptotic, and Regenerative Pathways in the Mouse Brain

(2018) James Ya Zhang et al.   JOURNAL OF NEUROTRAUMA

LRRK2 Contributes to Secondary Brain Injury Through a p38/Drosha Signaling Pathway After Traumatic Brain Injury in Rats

(2018) Qin Rui et al.   Frontiers in Cellular Neuroscience

Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury

(2018) Xu-Jia Zeng et al.   Cell Death & Disease

Sevoflurane post-conditioning attenuates traumatic brain injury-induced neuronal apoptosis by promoting autophagy via the PI3K/AKT signaling pathway

(2018) Hefan He et al.   Drug Design Development and Therapy

Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis

(2018) Ya-Ni Huang et al.   Scientific Reports

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Protects Against Neuronal Apoptosis via Activation of Akt/MDM2/p53 Signaling Pathway in a Rat Model of Intracerebral Hemorrhage

(2018) Weilin Xu et al.   Frontiers in Molecular Neuroscience

Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway

(2018) Fengchen Zhang et al.   Journal of Neuroinflammation

Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype

(2017) Jie Wu et al.   Journal of Neuroinflammation

P2X7 Participates in Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via MAPKs Signaling Pathways

(2017) Zunjia Wen et al.   NEUROCHEMICAL RESEARCH

Pathophysiology of Traumatic Brain Injury

(2017) Kirsty J. Dixon   Physical Medicine and Rehabilitation Clinics of North America

Recent Advances in Pathophysiology of Traumatic Brain Injury

(2017) Parmeet Kaur et al.   Current Neuropharmacology

p75 neurotrophin receptor and its novel interaction partner, NIX, are involved in neuronal apoptosis after intracerebral hemorrhage

(2016) Jiabing Shen et al.   CELL AND TISSUE RESEARCH

IL-33 Exerts Neuroprotective Effect in Mice Intracerebral Hemorrhage Model Through Suppressing Inflammation/Apoptotic/Autophagic Pathway

(2016) Yuan Gao et al.   MOLECULAR NEUROBIOLOGY

Past, Present, and Future of Traumatic Brain Injury Research

(2016) Gregory W.J. Hawryluk et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats

(2016) Jiang Wu et al.   STROKE

The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L

(2016) Victoria E Pedanou et al.   eLife

Hypoxia Activation of Mitophagy and Its Role in Disease Pathogenesis

(2015) Hao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720

(2015) Li Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Oxygen–Glucose Deprivation (OGD) Modulates the Unfolded Protein Response (UPR) and Inflicts Autophagy in a PC12 Hypoxia Cell Line Model

(2015) Theofanis Vavilis et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12

(2015) Barbora Veselá et al.   CONNECTIVE TISSUE RESEARCH

The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway

(2015) Feng Gao et al.   HUMAN MOLECULAR GENETICS

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory

(2015) Timothy E. O’Sullivan et al.   IMMUNITY

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

(2015) Nastasia Wilfinger et al.   Oncotarget

Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in Parallel with Reduced Apoptosis and Autophagy in Mice

(2014) Mingyang Zhang et al.   PLoS One

Up-regulated expression of Bnip3L after intracerebral hemorrhage in adult rats

(2013) Ying Rui et al.   JOURNAL OF MOLECULAR HISTOLOGY

Selective escape of proteins from the mitochondria during mitophagy

(2013) Shotaro Saita et al.   Nature Communications

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

(2010) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation

(2008) Abhinav Diwan et al.   CIRCULATION