Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma

Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

(2018) Jennifer Tsoi et al.   CANCER CELL

Toward Minimal Residual Disease-Directed Therapy in Melanoma

(2018) Florian Rambow et al.   CELL

Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation

(2017) Rasmus Siersbæk et al.   MOLECULAR CELL

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

(2017) Cedric R. Clapier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation

(2017) Himangi G. Marathe et al.   NUCLEIC ACIDS RESEARCH

Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma

(2017) Hannah E. Seberg et al.   Pigment Cell & Melanoma Research

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo

(2017) Shilpy Joshi et al.   PLoS Genetics

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype

(2016) D. Bossi et al.   Cancer Discovery

DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR

(2016) Goran Micevic et al.   Cell Reports

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

(2015) Temesgen D. Fufa et al.   HUMAN MOLECULAR GENETICS

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice

(2015) M. Achour et al.   HUMAN MOLECULAR GENETICS

The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy

(2015) Altaf A. Dar et al.   JNCI-Journal of the National Cancer Institute

What are super-enhancers?

(2015) Sebastian Pott et al.   NATURE GENETICS

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

(2015) Annelien Verfaillie et al.   Nature Communications

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment

(2015) Stefanie Riesenberg et al.   Nature Communications

New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis

(2015) Florian Rambow et al.   Cell Reports

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells

(2015) Dana Koludrovic et al.   PLoS Genetics

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

(2015) Patrick Laurette et al.   eLife

The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy

(2015) Altaf A. Dar et al.   JNCI-Journal of the National Cancer Institute

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma

(2013) Victoria Marsh Durban et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf V600E ::Pten –/– melanoma

(2013) M Scortegagna et al.   ONCOGENE

A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors

(2013) Melissa L. Harris et al.   PLoS Genetics

Chromatin-Remodeling Factor Brg1 Is Required for Schwann Cell Differentiation and Myelination

(2012) Matthias Weider et al.   DEVELOPMENTAL CELL

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas

(2011) William E. Damsky et al.   CANCER CELL

Chromatin remodeling complex NURF regulates thymocyte maturation

(2011) J. W. Landry et al.   GENES & DEVELOPMENT

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

(2011) T Strub et al.   ONCOGENE

General strategy to analyse melanoma in mice

(2011) Stuart J. Gallagher et al.   Pigment Cell & Melanoma Research

BRG1 expression is increased in human cutaneous melanoma

(2010) H. Lin et al.   BRITISH JOURNAL OF DERMATOLOGY

seqMINER: an integrated ChIP-seq data interpretation platform

(2010) Tao Ye et al.   NUCLEIC ACIDS RESEARCH

Inducible expression ofV600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality

(2010) Nathalie Dhomen et al.   Pigment Cell & Melanoma Research

Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice

(2009) Nathalie Dhomen et al.   CANCER CELL

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

(2009) B Keenen et al.   ONCOGENE

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

(2008) J. Goodall et al.   CANCER RESEARCH

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY