DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway

Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane

(2018) Tetsuo Mioka et al.   MOLECULAR BIOLOGY OF THE CELL

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

(2017) Yingli He et al.   JOURNAL OF CELL BIOLOGY

AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

(2017) Michael Schweizer et al.   Cancers

Plasticity of PI4KIII  interactions at the plasma membrane

(2015) J. Chung et al.   EMBO REPORTS

PKA-Dependent Phosphorylation of Ribosomal Protein S6 Does Not Correlate with Translation Efficiency in Striatonigral and Striatopallidal Medium-Sized Spiny Neurons

(2015) A. Biever et al.   JOURNAL OF NEUROSCIENCE

Resistance to Selumetinib (AZD6244) in Colorectal Cancer Cell Lines is Mediated by p70S6K and RPS6 Activation

(2014) Silvina Grasso et al.   NEOPLASIA

Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer

(2013) A. Khalaileh et al.   CANCER RESEARCH

DRAM1 Regulates Autophagy Flux through Lysosomes

(2013) Xing-Ding Zhang et al.   PLoS One

The Pro-Survival Role of Autophagy Depends on Bcl-2 Under Nutrition Stress Conditions

(2013) Hai-Dong Xu et al.   PLoS One

DRAM-1 encodes multiple isoforms that regulate autophagy

(2012) Li Yen Mah et al.   Autophagy

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells

(2012) S Galavotti et al.   ONCOGENE

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy

(2011) Jim O’Prey et al.   CELL CYCLE

Regulation of Ribosomal Protein S6 Phosphorylation by Casein Kinase 1 and Protein Phosphatase 1

(2011) John A. Hutchinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5′ terminal oligopyrimidine tract

(2010) P R Hagner et al.   ONCOGENE

Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death

(2009) Sun-Mi Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting the PI3K signaling pathway in cancer

(2009) Kwok-Kin Wong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE