Review
Oncology
Thineskrishna Anbarasan, Cheng Wei, Jeffrey C. Bamber, Richard G. Barr, Ghulam Nabi
Summary: Shear wave elastography is a promising imaging modality for detecting prostate cancer, with good sensitivity and specificity demonstrated in 16 published studies involving over 2200 patients.
Article
Immunology
Guosheng Yuan, Fuli Xie, Yangda Song, Qi Li, Rong Li, Xiaoyun Hu, Mengya Zang, Xiao Cheng, Guanting Lu, Jing Huang, Wenzhe Fan, Xiaoxiang Rong, Jian Sun, Jinzhang Chen
Summary: Baseline LS value of tumorous foci by SWE, before PD-1 inhibitor treatment in combination with lenvatinib, is a convenient predictor of PD-1 inhibitor efficacy in patients with advanced HCC, providing potential for pretreatment stratification to optimize treatment outcomes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Acoustics
Jacqueline Roots, Gabriel S. Trajano, Christopher Drovandi, Davide Fontanarosa
Summary: This study assessed the application of wave elastography in muscle stiffness assessment and compared the measurement results of two different devices. The study found significant differences in stiffness variability among different muscle regions, with the 75% location having the lowest variability and highest agreement, suggesting its use in future stiffness assessments.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Oncology
Wael Ageeli, Xinyu Zhang, Chidozie N. Ogbonnaya, Yuting Ling, Jennifer Wilson, Chunhui Li, Ghulam Nabi
Summary: This study explored the prostate cancer microenvironment and its association with peritumoral collagen in relation to cancer aggressivity. Different types and contents of collagen were found to vary with the Gleason grade of prostate cancer. Increased expression of Col1A1 in cancer tissues was linked to higher tissue modulus measured by ultrasound shear wave elastography. These findings contribute to a better understanding of clinically significant prostate cancer and its microenvironment.
Review
Radiology, Nuclear Medicine & Medical Imaging
Xia-Li Wang, Shu Lin, Guo-Rong Lyu
Summary: Changes in tissue stiffness can be identified earlier than clinical features, and elastography techniques provide valuable noninvasive measurement of mechanical properties. Ultrasound elastography plays a critical role in obstetrics and gynecology, especially for uterine tumor diagnosis, preterm birth prediction, and intrauterine insemination.
INSIGHTS INTO IMAGING
(2022)
Article
Acoustics
Wen-Bin Dai, Jun Xu, Bo Yu, Lin Chen, Yue Chen, Jiaz Zhan
Summary: This study investigated the correlation between shear wave elastography (SWE) and grade group (GG) of prostate cancer (PCa). The results demonstrated significant linear trends between SWE parameters and GG, with excellent diagnostic performance in predicting high GG in PCa.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Review
Acoustics
Gianluca Rossetto, Nicola Francesco Lopomo, Summaiva Zareen Shaikh
Summary: This study aimed to assess the effectiveness of ultrasonography (US) and ultrasound elastography (UE) in evaluating longitudinal sliding and stiffness of nerves. By analyzing 1112 publications from 2010 to 2021, the study found that US and UE are effective methods for assessing the mentioned parameters in lower extremity nerves. The study also identified differences in shear wave velocity (SWV) and shear modulus (SM) between control participants and those with leg pain or diabetic peripheral neuropathy (DPN).
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Medicine, General & Internal
Chang-Juan Hao, Wen-Li Xiao, Quan-Bin Zhang, Xiao-Mei Tan
Summary: Real-time shear-wave elastography can evaluate the stiffness of trapezius muscles in patients with trapezius myofascial pain syndrome, and it has been found that the stiffness of both affected and non-affected trapezius muscles increases, with the degree of increase positively correlated with the time of cervical forward leaning.
ANNALS OF MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Jacqueline Roots, Gabriel S. Trajano, Davide Fontanarosa
Summary: This article systematically reviewed the literature on the change in muscle stiffness as measured by ultrasound elastography in stroke survivors. The analysis of 29 relevant studies showed that ultrasound elastography has good validity in assessing muscle stiffness in stroke survivors and identified factors that affect muscle stiffness.
INSIGHTS INTO IMAGING
(2022)
Article
Biochemistry & Molecular Biology
Cristina Mihaela Roi, Andreea Borlea, Monica Simina Mihuta, Corina Paul, Dana Stoian
Summary: This study aims to assess the usefulness of shear-wave elastography (SWE) and strain elastography (SE) for identifying and monitoring thyroid gland changes in children diagnosed with chronic autoimmune thyroiditis (CAT). The results showed that both SWE and SE are useful for measuring thyroid tissue elasticity, with comparable diagnostic accuracy and reliability. The optimal cut-off values for predicting the presence of CAT in children were >1 for SR and >12 kPa for SWE.
Article
Medicine, General & Internal
Cyprian Olchowy, Kinga Grzech-Lesniak, Jakub Hadzik, Anna Olchowy, Mateusz Lasecki
Summary: The study showed that intensive exercise can significantly increase the stiffness of masticatory muscles, as measured by shear-wave elastography, while relaxation can lead to a significant decrease. The temporalis muscle exhibited significantly lower stiffness compared to the masseter muscle, with a significant correlation between the stiffness values of the two muscles.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qike Song, Yu Shi, Feng Gao, Yin Meng, Rui Yang, Yuanyuan Liu, Shiling Zhong, Yang Hong
Summary: This study aimed to evaluate the feasibility and reproducibility of multifrequency MR elastography (MRE) for diagnosing pancreatic ductal adenocarcinoma (PDAC). The results showed that MRE at frequencies of 30 and 40 Hz provided reliable measurements of pancreatic stiffness in healthy volunteers, while MRE at frequencies of 30-60 Hz was acceptable for PDACs (IQS >= 3, ICC and kappa >= 0.80).
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Chemistry, Analytical
Weirong Ge, Graham Brooker, Ritu Mogra, Jon Hyett
Summary: This study proposes a simulation-based method to resolve the challenges in measuring the nonlinear properties of cervical tissue. The study describes the nonlinear behavior using hyperelastic material models and compares the performance of different models in fitting the elastograms. The use of hyperelastic material models improves the consistency of measurements and has potential applications in clinical settings, but further refinements are needed.
Article
Radiology, Nuclear Medicine & Medical Imaging
Wael Ageeli, Cheng Wei, Xinyu Zhang, Magdalena Szewcyk-Bieda, Jennifer Wilson, Chunhui Li, Ghulam Nabi
Summary: The study found significant correlations between tissue stiffness measured by USWE and Gleason scores, as well as between Gleason scores and PI-RADS scores on mpMRI. High PIRADS on MRI and high stiffness on USWE (> 100 kPa) detected more than 80% and 90% high risk prostate cancer disease. However, there was a weak correlation coefficient of 0.231 between PI-RADS score and tissue stiffness in kPa.
INSIGHTS INTO IMAGING
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Domenico Albano, Mariachiara Basile, Salvatore Gitto, Carmelo Messina, Stefano Longo, Stefano Fusco, Ziga Snoj, Silvia Gianola, Silvia Bargeri, Greta Castellini, Luca Maria Sconfienza
Summary: This study compares pathological and healthy tendons using shear-wave elastography (SWE) technique.