Article
Computer Science, Artificial Intelligence
Huanqing Zhang, Jun Xie, Yi Xiao, Guiling Cui, Xinyu Zhu, Guanghua Xu, Qing Tao, Yuzhe Yang, Zhiyuan Ren, Min Li
Summary: This study analyzed the effects of steady-state auditory-visual motion stimuli on EEG and found that synchronous and asynchronous stimuli can enhance brain responses and activate areas involved in auditory and visual integration. Moreover, asynchronous stimuli activated the Anterior Cingulate region, indicating its involvement in conflicting processing of steady-state auditory-visual motion information.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Psychology, Clinical
Julia M. Longenecker, Victor J. Pokorny, Seung Suk Kang, Cheryl A. Olman, Scott R. Sponheim
Summary: The study examined how high-level visual processing is affected in psychosis and its relation to individual perceptual experiences. Findings showed that smaller N1 and larger NCL amplitudes were associated with object detection, and higher levels of perceptual absorption were correlated with reductions in N400 and a late positive PCA factor.
JOURNAL OF ABNORMAL PSYCHOLOGY
(2021)
Review
Neurosciences
Alexander Schielke, Bart Krekelberg
Summary: The author systematically reviewed studies on altered rhythmic responses to visual stimulation in individuals with schizophrenia using steady state visual evoked potentials (SSVEPs). The results indicated that people with schizophrenia exhibited decreased SSVEPs compared to controls across different frequencies and electrode locations, with null results being common. Most studies focused on frequencies within the alpha and beta bands, and investigations of the gamma band were rare.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Psychiatry
Tushar Chouhan, Melissa H. H. Black, Sonya Girdler, Sven Bolte, Tele Tan, Cuntai Guan
Summary: This study examines the task-induced functional brain networks of autistic and non-autistic individuals during a complex facial emotion recognition task. The results show significant differences in the functional networks between autistic and non-autistic adults, suggesting altered connectivity and EEG frequency bands in autistic individuals. These findings provide evidence for the neural mechanisms underlying the difficulties in facial emotion recognition observed in autism.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Behavioral Sciences
Gianluca Marsicano, Luca Casartelli, Alessandra Federici, Sara Bertoni, Lorenzo Vignali, Massimo Molteni, Andrea Facoetti, Luca Ronconi
Summary: This study reveals the spatially and temporally overrepresented encoding of visual information in children with autism spectrum disorder (ASD), leading to their peculiar hyperfocused attentional profile.
Article
Behavioral Sciences
Tessel Blom, Stefan Bode, Hinze Hogendoorn
Summary: Research demonstrates that the visual system utilizes two independent predictive mechanisms to reduce processing time when dealing with moving objects, predicting the position of the object in advance and adjusting the latency of neurons. Additionally, when the object unexpectedly reverses its trajectory, predictive activation needs to be readjusted, causing an additional latency disadvantage.
Article
Psychology, Developmental
Par Nystrom, Emily Jones, Fahimeh Darki, Sven Bolte, Terje Falck-Ytter
Summary: Research indicates individuals with ASD excel in local processing but struggle with integrating local features into global percepts. By comparing infants at risk for ASD to typically developing infants using SSVEP at 5 months old, different topographical organizations for global form and motion processing were observed. However, activation patterns for local visual change were surprisingly similar between the two groups, suggesting that perceptual abnormalities may contribute to the developmental pathways of ASD.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2021)
Article
Behavioral Sciences
Antigona Martinez, Russell H. Tobe, Pablo A. Gaspar, Daniel Malinsky, Elisa C. Dias, Pejman Sehatpour, Peter Lakatos, Gaurav H. Patel, Dalton H. Bermudez, Gail Silipo, Daniel C. Javitt
Summary: The study found deficits in facial emotion recognition ability in patients with schizophrenia and autism spectrum disorders, which may be related to reduced activation in early visual regions and the superior temporal sulcus.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Adrian R. Aguinaga, Daniel E. Hernandez, Angeles Quezada, Andres Calvillo Tellez
Summary: This paper introduces a novel two-stage deep learning model for recognizing emotional states by correlating facial expressions and brain signals. The model uses facial emotion recognition technique to create identifiers and extract relevant EEG record segments.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Brandon J. Lew, Anabel Salimian, Tony W. Wilson
Summary: The study found that alcohol use disorder is associated with reduced alpha brainwave responses, which are related to the severity of alcohol use symptoms but not cannabis use. The research also suggests that visual theta or gamma brainwave activity is not affected by alcohol or cannabis use disorders.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Martina Fanghella, Sebastian B. Gaigg, Matteo Candidi, Bettina Forster, Beatriz Calvo-Merino
Summary: This study investigates the reduced sensitivity of the somatosensory system to facial emotional expressions in individuals with autism spectrum disorder (ASD). The results show that ASD individuals have reduced amplitudes of somatosensory evoked potentials (SEPs) during the emotion task, suggesting a decreased recruitment of the somatosensory system during emotion discrimination in ASD.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Rhianan E. Ellis, Elizabeth Milne, Liat Levita
Summary: ASD individuals showed reduced short-term potentiation of VEPs following visual HFS compared to neurotypical controls. Those who reported being more sensitive to visual stimuli exhibited greater short-term potentiation.
BRAIN RESEARCH BULLETIN
(2021)
Article
Psychiatry
Michele Ribolsi, Giuliano Albergo, Federico Fiori Nastro, Martina Pelle, Valentina Contri, Cinzia Niolu, Vincenzo Di Lazzaro, Alberto Siracusano, Giorgio Di Lorenzo
Summary: Using the PAUSS scale, it was found that UHR patients have lower levels of autistic symptomatology compared to SCZ patients but higher than patients with mood disorders. There was a significant correlation between autistic symptomatology and the severity of formal thought disorders.
PSYCHIATRY RESEARCH
(2022)
Article
Pediatrics
Vinod Sharma, Arushi Gahlot Saini, Prahbhjot Malhi, Pratibha Singhi
Summary: The study found that about one-fourth of children with autism spectrum disorders also have epilepsy, with female gender and adverse perinatal events being independent risk factors. Subclinical or isolated EEG abnormalities are associated with abnormal neurological examination.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Article
Neurosciences
Judith Goris, Senne Braem, Shauni Van Herck, Jonas Simoens, Eliane Deschrijver, Jan R. Wiersema, Bryan Paton, Marcel Brass, Juanita Todd
Summary: Findings suggest that individuals with autism exhibit faster model updating during early sensory processing, resulting in less influence from the initial context.
JOURNAL OF NEUROSCIENCE
(2022)
Correction
Substance Abuse
A. Benjamin Srivastava, Juan Sanchez-Pena, Frances R. Levin, John J. Mariani, Gaurav H. Patel, Nasir H. Naqvi
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Muhammad O. Chohan, Jared M. Kopelman, Hannah Yueh, Zeinab Fazlali, Natasha Greene, Alexander Z. Harris, Peter D. Balsam, E. David Leonardo, Edgar R. Kramer, Jeremy Veenstra-VanderWeele, Susanne E. Ahmari
Summary: This study found that overexpression of Slc1a1 in dopaminergic neurons is associated with compulsive-like behavior in mice, suggesting that altered dopaminergic transmission may contribute to obsessive-compulsive disorder. These findings support the potential of normalizing EAAT3 activity as a treatment target.
MOLECULAR PSYCHIATRY
(2022)
Article
Behavioral Sciences
Antigona Martinez, Russell H. Tobe, Pablo A. Gaspar, Daniel Malinsky, Elisa C. Dias, Pejman Sehatpour, Peter Lakatos, Gaurav H. Patel, Dalton H. Bermudez, Gail Silipo, Daniel C. Javitt
Summary: The study found deficits in facial emotion recognition ability in patients with schizophrenia and autism spectrum disorders, which may be related to reduced activation in early visual regions and the superior temporal sulcus.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Review
Psychology, Developmental
Gonzalo Salazar de Pablo, Carolina Pastor Jorda, Julio Vaquerizo-Serrano, Carmen Moreno, Anna Cabras, Celso Arango, Patricia Hernandez, Jeremy Veenstra-VanderWeele, Emily Simonoff, Paolo Fusar-Poli, Paramala Santosh, Samuele Cortese, Mara Parellada
Summary: This meta-analysis found that antipsychotics and medications used to treat ADHD were significantly better than placebo in improving emotional dysregulation and irritability in individuals with ASD. Specifically, risperidone and aripiprazole showed efficacy in short-term treatment. However, other drug classes did not show evidence of efficacy. Lower efficacy was associated with comorbid epilepsy.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Neurosciences
David C. Gruskin, Gaurav H. Patel
Summary: Individuals' typical sensory experiences are related to the typicality of their brain activity. Recent research suggests that individual differences in this regard might be due to variability in focal neural processing. This study found that an individual's degree and spatial distribution of intersubject correlation (ISC) are closely associated with their brain's functional organization at rest.
Article
Psychology, Developmental
Miranda Zuniga-Kennedy, Micah Davoren, Lauren C. Shuffrey, Ruth Ann Luna, Tor Savidge, Vinay Prasad, George M. Anderson, Jeremy Veenstra-VanderWeele, Kent C. Williams
Summary: This study investigated the relationship between autism spectrum disorder (ASD) and gastrointestinal (GI) issues, and found an association between T-lymphocytes and elevated levels of whole blood serotonin (WB5-HT).
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Editorial Material
Neurosciences
Andrew T. Drysdale, Gaurav H. Patel
BIOLOGICAL PSYCHIATRY
(2022)
Article
Biochemistry & Molecular Biology
Muhammad O. Chohan, Hannah Yueh, Halli Fein, Jared M. Kopelman, Susanne E. Ahmari, Jeremy Veenstra-VanderWeele
Summary: Repeated amphetamine use leads to locomotor sensitization, which may be related to the development of psychosis and addiction. The interaction between dopaminergic and glutamatergic systems plays a significant role in amphetamine sensitization. However, the impact of chronic alterations in the expression of the excitatory amino acid transporter (EAAT3) on this phenomenon is still uncertain.
NEUROCHEMISTRY INTERNATIONAL
(2022)
Editorial Material
Psychology, Developmental
Pankhuree Vandana, Jeremy Veenstra-VanderWeele
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Neurosciences
Russell Tobe, Yajing Zhu, Teresa Gleissl, Simona Rossomanno, Jeremy Veenstra-VanderWeele, Janice Smith, Eric Hollander
Summary: High rates of placebo response are a problem in autism spectrum disorder (ASD) clinical trials. This study aimed to identify predictors of placebo response and their impact on clinical scales. The results showed that factors such as baseline function, trial duration, study site, and presence of other disorders influenced placebo response. These findings can help in managing and anticipating placebo response in drug development for ASD and other conditions.
NEUROPSYCHOPHARMACOLOGY
(2023)
Review
Behavioral Sciences
Ziwen Wang, Hannah Yueh, Mirabella Chau, Jeremy Veenstra-VanderWeele, Kally C. C. O'Reilly
Summary: Significant progress has been made in understanding the genetic and environmental risk factors for autism. With the use of optogenetic and chemogenetic tools, researchers can now manipulate neural circuits in model systems to study social function and dysfunction. This review examines the neural circuits associated with various aspects of social behavior and provides an interactive map of their overlaps. The findings suggest that some circuits are involved in multiple behavioral aspects, while others are specialized for specific social behaviors, highlighting knowledge gaps in our understanding of these circuits.
Article
Neurosciences
Gaurav H. Patel, David C. Gruskin, Sophie C. Arkin, Emery C. Jamerson, Daniel R. Ruiz-Betancourt, Casimir C. Klim, Juan P. Sanchez-Pena, Laura P. Bartel, Jessica K. Lee, Jack Grinband, Antigona Martinez, Rebecca A. Berman, Kevin N. Ochsner, David A. Leopold, Daniel C. Javitt
Summary: This study measured the functional connectivity of individuals with schizophrenia and healthy control subjects and found significant decreases in connectivity between brain regions involved in processing emotions and understanding others' mental states in schizophrenia patients. In the healthy control group, these regions were connected through the temporoparietal junction, while in schizophrenia patients, they were connected through the prefrontal cortex. These results suggest that connectivity anomalies can have widespread impacts on the network architecture and functioning of the brain.
BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE
(2023)
Article
Psychiatry
Russell H. Tobe, Lucia Tu, John R. Keefe, Melissa M. Breland, Benjamin A. Ely, Melissa Sital, Jasmin T. Richard, Umit Tural, Dan V. Iosifescu, Vilma Gabbay
Summary: This study aims to examine the factors influencing the expression of anhedonia. By evaluating physical, developmental, and clinical measures, the study found a correlation between personality traits and anhedonia, while diagnostic and symptom measures were not significant predictors of anhedonia.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Meeting Abstract
Neurosciences
Safia Mirza, Daniel Vieira, Nicholas Foley, Gaurav Patel
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
A. Benjamin Srivastava, Juan Sanchez-Pena, Frances Levin, John Mariani, Gaurav Patel, Nasir Naqvi
BIOLOGICAL PSYCHIATRY
(2022)
Review
Neurosciences
Maya Jammoul, Dareen Jammoul, Kevin K. Wang, Firas Kobeissy, Ralph G. Depalma
Summary: This article reviews the possible mechanisms by which traumatic brain injury (TBI) may stimulate the development of opioid use disorder (OUD) and discusses the interaction between these two processes. CNS damage due to TBI appears to drive adverse effects of subsequent OUD, with pain being a risk factor for opioid use after TBI.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Danusa Mar Arcego, Jan-Paul Buschdorf, Nicholas O'Toole, Zihan Wang, Barbara Barth, Irina Pokhvisneva, Nirmala Arul Rayan, Sachin Patel, Euclides Jose de Mendonca Filho, Patrick Lee, Jennifer Tan, Ming Xuan Koh, Chu Ming Sim, Carine Parent, Randriely Merscher Sobreira de Lima, Andrew Clappison, Kieran J. O'Donnell, Carla Dalmaz, Janine Arloth, Nadine Provencal, Elisabeth B. Binder, Josie Diorio, Patricia Pelufo Silveira, Michael J. Meaney
Summary: This study investigates the impact of environmental influences on mental health by integrating transcriptomic data from animal models with human data. The results suggest that hippocampal glucocorticoid-related transcriptional activity mediates the effects of early adversity on neural mechanisms implicated in psychiatric disorders.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Milenna T. van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora C. Kelsall, Marc J. Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M. Weissman, Jonathan Posner
Summary: This study found that maternal stress is associated with future depressive symptoms and alterations in microstructure of the dentate gyrus (DG) in offspring. These results were consistent across two independent cohorts.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Josephine C. McGowan, Liliana R. Ladner, Claire X. Shubeck, Juliana Tapia, Christina T. LaGamma, Amanda Anqueira-Gonzalez, Ariana DeFrancesco, Briana K. Chen, Holly C. Hunsberger, Ezra J. Sydnor, Ryan W. Logan, Tzong-Shiue Yu, Steven G. Kernie, Christine A. Denny
Summary: Traumatic brain injury (TBI) leads to fear generalization by altering fear memory traces, and this symptom can be improved with (R,S)-ketamine.
BIOLOGICAL PSYCHIATRY
(2024)