Article
Thermodynamics
Rui Long, Fan Wu, Xiyu Chen, Zhichun Liu, Wei Liu
Summary: Previous studies on the electrokinetic energy conversion focused on isothermal conditions, but this study systematically investigates the effects of temperature and membrane thermal conductivity. The findings suggest that under non-isothermal conditions, controlling membrane thermal conductivity and temperature differences can significantly improve the efficiency of energy conversion. Additionally, utilizing asymmetric temperatures and constructing tunable ionic current sources are proposed as potential strategies to enhance the performance of EKEC.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2021)
Article
Engineering, Biomedical
Hien Vu-Dinh, Wei Yun Tsao, Chun-Ping Jen
Summary: The study developed a microfluidic device for protein preconcentration and capture, achieving efficient dual purpose through fabrication of nano-interstices and modification of antibodies on gold electrodes for target protein capture.
BIOMEDICAL MICRODEVICES
(2022)
Article
Chemistry, Multidisciplinary
Hyukjin J. Kwon, Minsoo Lee, Seong Kyung Hong, Chan Park, Seong J. Cho, Geunbae Lim
Summary: The technology utilizes electrokinetics to achieve efficient emulsion separation, capable of separating nanoemulsions with ultrahigh flux. By arresting nano-oil droplets and allowing them to coalesce into larger droplets, they can be filtered by coarser membranes.
Article
Chemistry, Multidisciplinary
Chih-Chang Chang
Summary: This study investigated the electrokinetic energy conversion in a conical nanopore using a numerical model, revealing asymmetric characteristics in the streaming current, streaming potential, maximum power generation, maximum conversion efficiency, and flow rate under both forward and reverse pressure biases. The reverse pressure bias exhibited higher EKEC performance, attributed to asymmetric electrical resistance resulting from asymmetric ion depletion and ion enrichment.
Review
Chemistry, Analytical
Jongwan Lee, Jaeseok Lee, Minseok Kim
Summary: This article comprehensively reviews the fabrication methods and recent advances in bioanalysis of self-assembled particle membranes (SAPMs). The different fabrication methods of SAPM are categorized based on their working principle, and the application results for manipulating or analyzing ions, molecules, microbes, viruses, cells, and particles are enumerated. The review concludes by discussing the current limitations and the required efforts for solving them. It is hoped that this review article will provide guidance for researchers and expand the spectrum of applications for SAPMs in the future.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Chemical
Dongho Kim, Seungbin Ihm, Sudong Park, Yeonuk Yu, Rhokyun Kwak
Summary: The technique of preconcentration and filtration is essential in mechanical/biological/chemical engineering applications, with many strategies introduced to improve the process. Utilizing ion concentration polarization (ICP) desalination in a concentric geometry is a viable solution to the trade-off issue of preconcentration/filtration efficiency. This system can operate under large flow rate differences to produce highly concentrated solutions and desalted solutions with high water recovery rates.
Article
Chemistry, Analytical
Kira L. Rahn, Sommer Y. Osman, Quinlan G. Pollak, Robbyn K. Anand
Summary: The COVID-19 pandemic has emphasized the need for sensitive and selective point-of-care diagnostic sensors for early and rapid detection of infection. In this study, ion concentration polarization (ICP) is used to improve the sensitivity of paper-based lateral flow assays (LFAs) by preconcentrating the analyte, SARS-CoV-2 Spike protein (S-protein), directly over a test line. The results show that the described ICP-enhanced LFA can concentrate the S-protein by 21-fold, leading to a significant increase in signal compared to a regular LFA.
ANALYTICAL METHODS
(2023)
Article
Nanoscience & Nanotechnology
Ramadan Abu-Rjal, Yoav Green
Summary: The study shows that nanofluidic diodes exhibit unipolar and bipolar behaviors under different geometric and surface charge conditions, with bipolar and semi-bipolar systems showing a wider range of phenomena. Furthermore, the investigation of system characteristics includes not only the steady-state results, but also the time-dependent rectification factors and transport numbers in transient conditions.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Antonio Cobelo-Garcia, Mirsya E. Mulyani, Jorg Schafer
Summary: The determination of palladium in environmental samples by ICP-MS is challenging due to extensive interferences, but an interference-free methodology for the determination of Pd in natural waters has been successfully achieved by online matrix separation and preconcentration. This method allows for the detection of dissolved Pd in natural samples at low, ambient concentrations, providing valuable data for understanding the behavior of Pd in natural waters.
Article
Biochemical Research Methods
Junwoo Lee, Yong Kyoung Yoo, Dohwan Lee, Cheonjung Kim, Kang Hyeon Kim, Seungmin Lee, Seungmin Kwak, Ji Yoon Kang, Hyungsuk Kim, Dae Sung Yoon, Don Hur, Jeong Hoon Lee
Summary: Ion concentration polarization (ICP) is a preconcentration technique with the potential for high preconcentration factor, but faces challenges of instability and low efficiency under physiological conditions. A sequentially driven ICP process has been proposed to enhance the preconcentration of highly ionic raw samples without increasing the electric field, resulting in significant preconcentration factor and signal enhancement in enzyme-linked immunosorbent assay (ELISA) using tau protein.
Review
Chemistry, Analytical
Aparna Krishnamurthy, Robbyn K. K. Anand
Summary: Microscale extraction offers advantages in sample throughput, specificity, and efficiency, which can be utilized to improve assays, sensor signals, and sample purification. Electrokinetic microextraction techniques have gained attention for their control over mass transport, ease of actuation, and portability, making them suitable for microscale and point-of-care devices. While most articles focus on analyte preconcentration using ion concentration polarization (ICP), few have explored the subsequent extraction step. This review discusses recent advancements in ICP-mediated microfluidic extraction methods and their potential for further development.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Minsoo Lee, Hyukjin J. Kwon, Geunbae Lim
Summary: The novel multiscale-porous anion exchange membrane (MP-AEM) enables convenient and scalable electrokinetic concentration of cationic species by overcoming the intrinsic limitations of traditional AEM materials. The MP-AEM-embedded electrokinetic concentrator is fabricated in a highly simplified manner with only a simple insertion and assembly process. The concentration performance of the MP-AEM-embedded concentrator is demonstrated to enrich positively charged samples with enrichment factors of up to 500, making cationic electrokinetic concentration more accessible and scalable for various applications.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Biochemical Research Methods
Fatima Flores-Galicia, Alexander Eden, Antoine Pallandre, Sumita Pennathur, Anne-Marie Haghiri-Gosnet
Summary: This study investigates the influence of key parameters such as electrolyte concentration, surface charge density, and applied electric field on ion concentration polarization dynamics in micro-/nanofluidic devices. By tuning the system for analyte focusing at the charge, excluding microchannel, nanochannel electrical double layer (EDL) interface, the greatest enhancement is observed. Additionally, adding extra nanochannels oriented parallel to the electric field can increase perm-selectivity and enhance focusing at the EDL interfaces.
Article
Biochemistry & Molecular Biology
Nikolett Czipa, Bela Kovacs, Lorand Alexa, Mehari Gebreyesus
Summary: This study measured macro, micro, and trace elemental concentrations in Eritrean acacia honey samples and found significant differences among specific honey samples. The elemental concentrations in these honeys are influenced by the characteristics of the collecting area. The consumption of these honeys does not significantly contribute to nutrition reference values and presents no risk to the human body.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Biochemical Research Methods
Meng Zhiyue, Yuan Xichen, Ren Li, Yang Yang, Feng Huicheng, Shang Peng
Summary: The limitation of biochemical detection technology in sensitivity to micro-samples is attributed to the relatively high complexity of the samples. The ion-concentration polarization phenomenon has gained widespread interest in the application of microfluidic technology, especially in paper-based microfluidic chips.
Review
Chemistry, Multidisciplinary
Qiu-Yang Xu, Zheng Tan, Xue-Wei Liao, Chen Wang
Summary: Early and precise diagnosis are crucial for timely treatment and increased success rate of treatments. Nanoscale metal-organic frameworks (nMOFs) have been widely used in biomedicine due to their structural designability and property tunability. This review summarizes the recent advancements of nMOFs-based biosensors for biomarker detection in different sensing modes, including fluorescent sensing, colorimetric sensing, electrochemical sensing, and surface-enhanced Raman scattering (SERS) sensing.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Xiaoyu Wang, Wenchao Hu, Xing-Hua Xia, Chen Wang
Summary: A surfactant-assisted method is used to prepare 2D metal-organic frameworks based single zinc sites nanozyme with high loading weight ratio. The nanozyme exhibits peroxidase-like activity and shows potential in antibiofilm therapy under low concentration of H2O2. This work not only provides a method for fabricating MOF-based single sites nanozyme, but also demonstrates its application in antibiofilm therapy.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jin Wang, Chen Wang, Jing-Juan Xu, Xing-Hua Xia, Hong-Yuan Chen
Summary: Integrating discrete plasmonic nanoparticles into assemblies can induce plasmonic coupling, leading to stronger electromagnetic field enhancement effects. This enables better performance in plasmon-based applications, such as enhanced fluorescence and Raman effects, holding great potential for trace analyte detection and nanomedicine. The recent advances in various plasmonic nanoassemblies and their applications in biosensing and cell imaging are discussed, along with the fabrication strategies for self-assembled plasmonic nanostructures.
CHINESE CHEMICAL LETTERS
(2023)
Article
Engineering, Environmental
Shuyu Jia, Xinran Gao, Yangyang Zhang, Peng Shi, Chen Wang, Qing Zhou, Lin Ye, Xu-Xiang Zhang
Summary: Although tertiary wastewater treatment processes (TWTPs) have high removal efficiency for chemical pollutants, their impact on microbial risk mitigation is uncertain. This study used metagenomic approaches to investigate the changes of antibiotic resistance genes (ARGs), virulence factor genes (VFGs), and their co-occurrence during multiple TWTPs. It was found that the denitrifying biofilter (DB) increased the abundance of antibiotic-resistant bacteria and ARGs, as well as the relative abundance of ARGs and VFGs through the enrichment of multidrug resistance and offensive genes. Complementary microbial risk reduction was achieved through ultraviolet and constructed wetland treatment. The study provides new insights into the effects of TWTPs on the antibiotic resistome and VFG profiles, and aids in selecting appropriate TWTPs for microbial risk mitigation.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Shi-Shu Yang, Chen Wang, Yu-Fei Jiang, Hua Zhang
Summary: In this study, Ti3AlC2 nanomaterials were employed as an affinity adsorbent for the dual-selective capture of phosphopeptides and glycopeptides. The nanomaterials showed excellent detection sensitivity for phosphopeptides and good selectivity for glycopeptides. They were successfully used for the enrichment of phosphopeptides and glycopeptides from biological samples, leading to the identification of unique phosphopeptides and glycopeptides. This work opens up new opportunities for sample preparation in phosphoproteomics and glycoproteomics research.
Article
Chemistry, Multidisciplinary
Zheng Tan, Jin Wang, Li Xu, Qijun Zheng, Lingfei Han, Chen Wang, Xuewei Liao
Summary: A gas sensor based on 2D covalent organic framework (COF) and Raman technology was developed, which showed excellent performance in the detection of volatile organic compounds (VOCs). The sensor effectively preconcentrated VOCs by adsorbing gas molecules with high capacity and fast kinetics. The Raman intensity was enhanced through the local surface plasmon resonance effect, resulting in improved detection sensitivity and reliability. This microfluidic platform provides a simple, sensitive, and fast method for VOCs sensing and distinguishing.
Article
Chemistry, Multidisciplinary
Mengyuan Chen, Kun Yang, Jin Wang, Hanjun Sun, Xing-Hua Xia, Chen Wang
Summary: In response to the energy crisis, the osmotic energy conversion method utilizing the salinity gradient between seawater and freshwater is an effective way to obtain energy. However, the majority of nanofluidic membranes used for osmotic energy generation are cation-selective. This study presents the synthesis of an anion-selective membrane by growing imine-bridged covalent organic framework (COF) on ordered anodic aluminum oxide (AAO) at room temperature. The resulting membrane exhibits excellent ionic current rectification property, high ion selectivity and permeability, and successfully harvests salinity gradient energy.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Analytical
Lingfei Han, Yingjiu Zhou, Zheng Tan, Hongtan Zhu, Yexin Hu, Xiao Ma, Feng Zheng, Feng Feng, Chen Wang, Wenyuan Liu
Summary: This study utilized the characteristics of gamma H2AX as a confined target and constructed a gamma H2AX immunosensor based on gold nanoprobes, achieving accurate assessment of genotoxicity. The proposed method allows for in situ real-time analysis of intranuclear targets at the single-living-cell level, simplifying the structure of SERS probes and the operation process.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jin Wang, Zheng Tan, Chengcheng Zhu, Li Xu, Xing-Hua Xia, Chen Wang
Summary: A size-controlled Au@Cu-BTC nanomaterial was synthesized for specific and simultaneous imaging of multiple protein expression levels on cell membranes. The nanoprobes showed good specificity, stability, and multichannel imaging capabilities. This nanomaterial holds promising applications in biosensing and therapeutic fields, enabling simultaneous detection of varied proteins on cell surfaces with high sensitivity and accuracy.
Review
Chemistry, Multidisciplinary
Yao Zhang, Huijie Wang, Jin Wang, Lulu Li, Hanjun Sun, Chen Wang
Summary: The potential of harnessing osmotic energy from the interaction between seawater and river water has been recognized. The reverse electrodialysis (RED) technology, combined with nanofluidic membranes, offers a promising solution for efficient harvesting of renewable osmotic energy. This review focuses on the structure, fabrication techniques, materials selection, and challenges in asymmetric membranes based on anodic aluminum oxide (AAO) for osmotic energy conversion.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Lingfei Han, Chengcheng Zhu, Zheng Tan, Jin Wang, Xuewei Liao, Xing-Hua Xia, Chen Wang
Summary: A label-free magnetic surface enhanced Raman scattering (SERS) platform was developed using superparamagnetic Fe3O4 nanoparticles as cores and Au layers as shells. This platform can effectively distinguish exosomes from different cell sources for cancer diagnosis with high sensitivity and specificity within a 95% confidence interval. The designed integrated platform for separation and detection has great potential in clinical diagnostics as a low-cost and efficient exosome analysis method.
CHEMICAL COMMUNICATIONS
(2023)
Article
Materials Science, Biomaterials
Xuewei Liao, Wenjun Tong, Li Dai, Lingfei Han, Hanjun Sun, Wenyuan Liu, Chen Wang
Summary: Gold nanoparticles (AuNPs) with dual enzyme-like activity were used to detect the concentration of bacteria and glucose. The method showed high sensitivity and a good linear relationship. This study provides a new approach for the construction of biosensors and clinical detections.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Computer Science, Software Engineering
Piaopiao Yu, Jie Guo, Fan Huang, Zhenyu Chen, Chen Wang, Yan Zhang, Yanwen Guo
Summary: Inserting 3D virtual objects into real-world images is a common practice in photo editing and augmented reality. Generating visually realistic shadows for these objects is a challenge, especially when projecting shadows from real objects onto virtual ones. In this paper, we propose an end-to-end solution called ShadowMover that automatically projects real shadows onto virtual objects for outdoor scenes. Our method uses the Shifted Shadow Map to encode the binary mask of shifted real shadows, and a CNN-based shadow generation model to generate plausible shadows on inserted virtual objects. Extensive experiments demonstrate the effectiveness of our approach.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2023)
Article
Chemistry, Multidisciplinary
Tingting Xu, Chen Wang, Sijie Jiang, Tingting Yang, Xueming Wu
Summary: An effective approach to biotransform luteolin glycosides in hydrophilic organic solvents was developed using Bacillus cereus A46 cells. The addition of DMSO greatly enhanced the solubility of luteolin and regulated the formation of the desired product of luteolin 7-O-beta-glucoside.
Review
Chemistry, Multidisciplinary
Yang Liu, Pengfei Lei, Xuewei Liao, Chen Wang
Summary: This review article summarizes recent advances in nanoscale metal-organic frameworks (nMOFs) as nanoplatforms for drug delivery and cancer therapy. Different techniques using nMOFs are systematically summarized, and their advantages in biomedical applications are highlighted.
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
(2022)
