Article
Chemistry, Multidisciplinary
Shengmei Guo, Yuyang Zhang, Jianyan Huang, Lin Kong, Jiaxiang Yang
Summary: This study developed a dual-state blue emission material with high emission efficiency in both solution and solid states, successfully synthesizing and investigating its fluorescence behavior mechanism. The material can be utilized for picric acid detection in solution and exhibits high emission performance in the solid state.
Review
Chemistry, Analytical
Ankita Roy, Mahasweta Nandi, Partha Roy
Summary: The development of dual chemosensors is gaining special attention due to its advantages over single analyte chemosensors. By compiling published pure organic compounds as dual chemosensors, a library can be built to provide ready information in this field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Pawan Kumar Sada, Amit Bar, Amanpreet Kaur Jassal, Alok Kumar Singh, Laxman Singh, Abhishek Rai
Summary: A new rhodamine-6G hydrazone (RHMA) was synthesized using rhodamine-6G hydrazide and 5-Allyl-3methoxysalicylaldehyde. RHMA was fully characterized and showed selective recognition of Cu2+ and Hg2+ among other metals. The absorbance and fluorescence of RHMA changed significantly with the presence of Cu2+ and Hg2+, resulting in a visual color change. RHMA also showed reversibility in the presence of EDTA2- ions and can be applied as a test strip for detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Varun Rawat, Arkadi Vigalok
Summary: Fluorescent calix[4]arene scaffolds with electron-rich carbazole moiety conjugated at the lower rim have been prepared. The electronic properties of the distal phenolic ring play a major role in the fluorescence quenching in the presence of the N-methyl pyridinium guest. Introducing an electron-donating piperidine fragment into that ring significantly increases the host-guest interactions, while introducing the same fragment into the proximal phenolic ring weakens the fluorescence response.
Article
Chemistry, Analytical
Wei-Yi Zhang, Tao Tian, Li-Jing Peng, Hang-Yu Zhou, Hao Zhang, Hua Chen, Feng-Qing Yang
Summary: In this study, a paper-based analytical device combined with a smartphone was developed for the dual-mode fluorescent and colorimetric detection of beta-glucosidase activity. The device utilizes the hydrolysis of a substrate to generate fluorescent and colorimetric signals, which are then captured and analyzed using a smartphone. This method offers a simple, environmentally friendly, and cost-effective approach for beta-glucosidase activity detection.
Article
Chemistry, Multidisciplinary
Sohom Kundu, Amit Ghosh, Indrajit Paul, Michael Schmittel
Summary: A multicomponent pseudorotaxane quadrilateral was reversibly toggled between three distinct switching states. Switching in the forward and reverse directions was achieved by adding specific ions or compounds, triggering different chemical reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Review
Chemistry, Inorganic & Nuclear
Fang Wang, Kaijie Wang, Qing Kong, Jing Wang, Dazhou Xi, Bowen Gu, Sheng Lu, Tingwen Wei, Xiaoqiang Chen
Summary: This review describes the development of fluorescence probes for Zn2+ since 2015, highlighting their high sensitivities and selectivities. The probes are organized according to different fluorophore families and mainly discussed based on their mode of action.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: A DNA sensing platform with endogenous stimuli-responsive and ultrasensitive characteristics, incorporating a logic gate biocomputation, has been developed for precise cell subtype identification in disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Spectroscopy
Ananta Hazra, Pritam Ghosh, Partha Roy
Summary: In this study, a rhodamine-based compound (RBO) was reported as a selective fluorescent chemosensor for the detection of Al3+ and Hg2+ ions. It exhibited a high fluorescence enhancement and low detection limits, and could also be used for constructing logic gates.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Dhanushkodi Mohanasundaram, R. Bhaskar, Gujuluva Gangatharan Vinoth Kumar, Jegathalaprathaban Rajesh, Gurusamy Rajagopal
Summary: The newly designed and synthesized probe L demonstrated good metal recognition ability, with high selectivity towards Cd2+. It can form a 2:1 complex with Cd2+ and was successfully utilized for the quantification of Cd2+ in water samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Gabriella Munzi, Salvatore Failla, Santo Di Bella
Summary: This study demonstrates the fast and selective detection of biogenic amines using a dinuclear Zn(ii) Schiff-base complex, showing high sensitivity even in the presence of other substances. The method allows for accurate quantification of biogenic amines in a fish matrix through simple colorimetric or fluorometric measurements.
Article
Environmental Sciences
Zefeng Li, Meng Li, Bin Tan, Ning Du, Qian Zhang, Chengwei Li, Yibo Zhang, Jiawei Li, Jiayi Li
Summary: This study established an adaptable biological Fenton-like system for the efficient degradation of organic contaminants. By optimizing the pH range, selecting suitable oxidizing species, and enhancing glucose conversion, effective degradation of 3,4-dimethylaniline was achieved.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Suman Yadav, Anand Kumar Pandey, Suresh Kumar Dubey
Summary: The study identified a novel strain with highly efficient thermostable, glucose tolerant beta-glucosidases. Molecular docking simulations revealed the enzyme's ability to effectively hydrolyze beta-1-4 linkages with specific contributing amino acids. Additionally, a distinct glucose-binding site was found, suggesting limited competitive inhibition by glucose, making this enzyme a promising candidate for cellulose degradation and various industrial applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Analytical
Ning Xia, Yong Chang, Qian Zhou, Shoujie Ding, Fengli Gao
Summary: This review systematically introduces the recent advancements of MOFs-based fluorescent chemosensors and biosensors, focusing on the sensing mechanisms and analytes. It emphasizes the potential value of MOFs-based sensing platforms in environmental monitoring and clinical diagnosis.
Review
Chemistry, Multidisciplinary
Hai-Hao Han, Han-Min Wang, Paramesh Jangili, Mingle Li, Luling Wu, Yi Zang, Adam C. Sedgwick, Jia Li, Xiao-Peng He, Tony D. James, Jong Seung Kim
Summary: Cancer is a major global health problem, with millions of people diagnosed each year. Current chemotherapy options lack selectivity for cancer cells, are prone to resistance, and have toxicities. Researchers have focused on developing prodrug-based strategies to overcome these limitations. This review discusses recently developed prodrug strategies for cancer therapy and highlights the importance of targeting specific biomarkers in the tumor microenvironment and overexpressed in cancer cells. The advantages and limitations of each approach are also discussed.
CHEMICAL SOCIETY REVIEWS
(2023)
Editorial Material
Chemistry, Multidisciplinary
Run Zhang, Tony D. James
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Review
Chemistry, Inorganic & Nuclear
Min Ge, Shouxin Liu, Jian Li, Meng Li, Shujun Li, Tony D. James, Zhijun Chen
Summary: Luminescent materials have great potential in various fields, and the conversion of biomass resources into functional luminescent materials has gained significant attention. However, only a few reviews have focused on this area. This review aims to address this gap and introduce the types of biomass sources available for the preparation of luminescent materials. It will cover the structure-optical performance correlation, preparation and optical properties, potential applications, and future challenges and perspectives of biomass-derived luminescent materials.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Nanoscience & Nanotechnology
Tianhong Wu, Shiqing Huang, Xing Feng, Xiaogang Liu, Tony D. James, Xiaolong Sun, Xuhong Qian
Summary: In this research, a photoluminescent platform using amine-coupled fluorophores was developed. The fluorescence turn-on mechanism was proposed to be charge separated induced energy radiative transition for the amine-coupled fluorophore. By utilizing the conjugate acceptor, a new fluorogenic approach was established, allowing for selective detection of cysteine under neutral aqueous conditions. This research also successfully constructed a drug delivery system with controlled release of sulfhydryl drug.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Si-Lin Xu, Fang-Fang Guo, Zhi-Hong Xu, Yuan Wang, Tony D. James
Summary: A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, which exhibits colorimetric fluorescent response towards hypochlorite (ClO-) with a low LOD (0.082 mu M), and turn-on response to viscosity changes. Due to its low cytotoxicity and good biocompatibility, probe 1 is used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Multidisciplinary Sciences
Yingxiang Zhai, Shujun Li, Jian Li, Shouxin Liu, Tony D. James, Jonathan L. Sessler, Zhijun Chen
Summary: By treating natural wood with magnesium chloride, it can be converted into a viable room temperature phosphorescence (RTP) material called C-wood. C-wood exhibits intense RTP emission and can be used to create afterglow wood sculptures and printable afterglow fibers for luminescent plastics via 3D printing.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Meng Li, Quanyu Shi, Ningxin Song, Zhijun Chen, Lidong Wang, Tony D. James
Summary: A supramolecular artificial light-harvesting system is constructed in an aqueous environment using carbon dots and TMPyP via electrostatic interactions. The energy transfer from the CDs to the TMPyP occurs upon UV excitation. The CDs-TMPyP system is used as a sensor for Hg(II) in an aqueous solution, and a functional material for the detection and removal of Hg(II) is fabricated by integrating the CDs-TMPyP into a polymer network.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Analytical
Peng Zhang, Xuechuan Wang, Xiao Wang, Chusen Huang, Tony D. James, Xiaolong Sun, Xuhong Qian
Summary: This research developed small molecule-based fluorescent probes for chemoselective labeling of vicinal dithiol-containing proteins (VDPs) in live cells, allowing the study of intracellular redox homeostasis. The probes achieved selective labeling of VDPs through thiol-thiol substitutions on bisvinylogous thioester conjugated acceptors (IDAs). The probes demonstrated high sensitivity, low limit of detection, and selectivity for labeling vicinal dithiols on reduced bovine serum albumin, as well as successfully labeling endogenous VDPs at different redox states in live cells.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yujie Geng, Hanchen Zhang, Guoyang Zhang, Jiaying Zhou, Mingguang Zhu, Lijun Ma, Xuefei Wang, Tony D. D. James, Zhuo Wang
Summary: Schizophrenia is a common mental disorder with unclear mechanisms. This research developed a near-infrared fluorescent probe for noninvasive detection of endogenous superoxide anion (O-2 (-)) in the brain, providing direct evidence for the relationship between oxidative stress, neuroinflammation, and schizophrenia. Furthermore, the study confirmed the burst of O-2(-) in the brains of first-episode schizophrenic mice and assessed the effect of two atypical antipsychotic drugs on redox homeostasis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Daniel N. Mangel, Gabriel J. Juarez, Stephanie H. Carpenter, Axel Steinbrueck, Vincent M. Lynch, Jian Yang, Adam C. Sedgwick, Aaron Tondreau, Jonathan L. Sessler
Summary: In this study, the use of deferasirox derivatives as lanthanide chelators was reported, and the complexation behavior of these derivatives in solid state and solution was investigated. High selectivity for Lu(III) was observed in competitive precipitation.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Meng Li, Quanyu Shi, Ningxin Song, Yumeng Xiao, Lidong Wang, Zhijun Chen, Tony D. James
Summary: The shortage of freshwater resources caused by heavy metal pollution is a global issue that greatly impacts environmental protection and human health. Developing innovative and cost-effective materials for detecting and removing heavy metal ions is crucial.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Ruixia Liu, Hongda Guo, Mengnan Cao, Ben Dang, Yingxiang Zhai, Shouxin Liu, Shujun Li, Jian Li, Tony D. James, Zhijun Chen
Summary: An efficient top-down method is developed for processing natural wood into RTP films with a lifetime of approximate to 241.9 ms. The treated wood is converted into W-film with good tensile strength, triggering RTP emission and exhibiting energy transfer properties with Rhodamine B. This research is expected to provide a convenient and sustainable method for preparing RTP films.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Fei Cheng, Taotao Qiang, Mingli Li, Tony D. James
Summary: A novel zinc diporphyrin molecular graphene Oligo-Zn-Por photocatalyst was synthesized and showed high Cr(vi) reduction efficiency and cycling ability under sunlight.
CATALYSIS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kai-Cheng Yan, Jordan E. E. Gardiner, Adam C. C. Sedgwick, Naing Thet, Rachel A. A. Heylen, Tony D. D. James, A. Toby A. Jenkins, Xiao-Peng He
Summary: A new fluorescent probe was developed to determine the NTR activity of different bacterial species under various growth conditions, which can be applied in complex clinical environments with high sensitivity and detection accuracy for both planktonic cultures and biofilms.
CHEMICAL COMMUNICATIONS
(2023)
