期刊
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
卷 -, 期 145, 页码 -出版社
JOURNAL OF VISUALIZED EXPERIMENTS
DOI: 10.3791/59163
关键词
Neuroscience; Issue 145; Organotypic cultures; immunostaining; myelin; central nervous syste; cerebellum; repair
资金
- INSERM
- ICM
- ARSEP [R13123DD]
- ANR [R17127DD]
- FRM fellowship [SPF20110421435, FDT20170437332]
In the nervous system, myelin is a complex membrane structure generated by myelinating glial cells, which ensheathes axons and facilitates fast electrical conduction. Myelin alteration has been shown to occur in various neurological diseases, where it is associated with functional deficits. Here, we provide a detailed description of an ex vivo model consisting of mouse organotypic cerebellar slices, which can be maintained in culture for several weeks and further be labeled to visualize myelin.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据