PIEZO1 Hypomorphic Variants in Congenital Lymphatic Dysplasia Cause Shape and Hydration Alterations of Red Blood Cells

Human phenotypes caused by PIEZO1 mutations; one gene, two overlapping phenotypes?

(2018) Silvia Martin-Almedina et al.   JOURNAL OF PHYSIOLOGY-LONDON

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Genotype-phenotype correlation and risk stratification in a cohort of 123 hereditary stomatocytosis patients

(2018) Andolfo Immacolata et al.   AMERICAN JOURNAL OF HEMATOLOGY

PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis

(2017) Immacolata Andolfo et al.   HAEMATOLOGICA

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Heterologous Expression of the Piezo1-ASIC1 Chimera Induces Mechanosensitive Currents with Properties Distinct from Piezo1

(2017) Qiancheng Zhao et al.   NEURON

Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization

(2017) Adrienne E. Dubin et al.   NEURON

PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis

(2017) Immacolata Andolfo et al.   HAEMATOLOGICA

New insights on hereditary erythrocyte membrane defects

(2016) Immacolata Andolfo et al.   HAEMATOLOGICA

PIEZO1 gene mutation in a Japanese family with hereditary high phosphatidylcholine hemolytic anemia and hemochromatosis-induced diabetes mellitus

(2016) Shinsaku Imashuku et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Piezo1-dependent regulation of urinary osmolarity

(2016) Joana Raquel Martins et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

New insights on hereditary erythrocyte membrane defects

(2016) Immacolata Andolfo et al.   HAEMATOLOGICA

Authors response to "Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia"

(2015) B. E. Shmukler et al.   HAEMATOLOGICA

Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia

(2015) B. E. Shmukler et al.   HAEMATOLOGICA

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

(2015) Viktor Lukacs et al.   Nature Communications

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

Authors response to "Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia"

(2015) B. E. Shmukler et al.   HAEMATOLOGICA

Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia

(2015) B. E. Shmukler et al.   HAEMATOLOGICA

Ionic Selectivity and Permeation Properties of Human PIEZO1 Channels

(2015) Radhakrishnan Gnanasambandam et al.   PLoS One

Hereditary xerocytosis revisited

(2014) Natasha M. Archer et al.   AMERICAN JOURNAL OF HEMATOLOGY

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

(2013) I. Andolfo et al.   BLOOD

Dehydrated stomatocytic anemia due to the heterozygous mutation R2456H in the mechanosensitive cation channel PIEZO1: a case report

(2013) Boris E. Shmukler et al.   BLOOD CELLS MOLECULES AND DISEASES

Piezo1 plays a role in erythrocyte volume homeostasis

(2013) A. Faucherre et al.   HAEMATOLOGICA

Hereditary xerocytosis and familial haemolysis due to mutation in the PIEZO1 gene: a simple diagnostic approach

(2013) M. B. Sandberg et al.   International Journal of Laboratory Hematology

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels

(2013) Juliette Albuisson et al.   Nature Communications

Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis

(2012) R. Zarychanski et al.   BLOOD

The role of Drosophila Piezo in mechanical nociception

(2012) Sung Eun Kim et al.   NATURE

Digenic inheritance and Mendelian disease

(2012) James R Lupski   NATURE GENETICS

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE