Melatonin Therapy Modulates Cerebral Metabolism and Enhances Remyelination by Increasing PDK4 in a Mouse Model of Multiple Sclerosis

Spasticity Treatment Ameliorates the Efficacy of Melatonin Therapy in Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model of Multiple Sclerosis

(2018) Majid Ghareghani et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neuroprotective Effects of Melatonin on Experimental Allergic Encephalomyelitis Mice Via Anti-Oxidative Stress Activity

(2018) Ting Long et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Efficacy of Melatonin on Serum Pro-inflammatory Cytokines and Oxidative Stress Markers in Relapsing Remitting Multiple Sclerosis

(2018) Angélica L. Sánchez-López et al.   ARCHIVES OF MEDICAL RESEARCH

Melatonin therapy reduces the risk of osteoporosis and normalizes bone formation in multiple sclerosis

(2017) Majid Ghareghani et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The Peroxisome-Mitochondria Connection: How and Why?

(2017) Marc Fransen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis

(2017) StevenM LeVine et al.   Neural Regeneration Research

Expression profiles of cholesterol metabolism-related genes are altered during development of experimental autoimmune encephalomyelitis in the rat spinal cord

(2017) Irena Lavrnja et al.   Scientific Reports

Melatonin Increases Oligodendrocyte Differentiation in Cultured Neural Stem Cells

(2016) Majid Ghareghani et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Melatonin exacerbates acute experimental autoimmune encephalomyelitis by enhancing the serum levels of lactate: A potential biomarker of multiple sclerosis progression

(2016) Majid Ghareghani et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis

(2016) Shyi-Jou Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neurodegeneration in multiple sclerosis and neuromyelitis optica

(2016) Izumi Kawachi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

ExtracellularN-Acetylaspartate in Human Traumatic Brain Injury

(2016) Richard J. Shannon et al.   JOURNAL OF NEUROTRAUMA

Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis

(2016) Frédéric Sedel et al.   NEUROPHARMACOLOGY

Melatonin controls experimental autoimmune encephalomyelitis by altering the T effector/regulatory balance

(2015) Nuria Álvarez-Sánchez et al.   BRAIN BEHAVIOR AND IMMUNITY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Differential brain and spinal cord cytokine and BDNF levels in experimental autoimmune encephalomyelitis are modulated by prior and regular exercise

(2013) Danielle Bernardes et al.   JOURNAL OF NEUROIMMUNOLOGY

One calcitriol dose transiently increases Helios+FoxP3+ T cells and ameliorates autoimmune demyelinating disease

(2013) Faye E. Nashold et al.   JOURNAL OF NEUROIMMUNOLOGY

White matter lactate – Does it matter?

(2013) J.E. Rinholm et al.   NEUROSCIENCE

Cerebral Developmental Abnormalities in a Mouse with Systemic Pyruvate Dehydrogenase Deficiency

(2013) Lioudmila Pliss et al.   PLoS One

Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Metabolic Interaction and Neuro-metabolic Disorders

(2012) Mithilesh Kumar Jha et al.   Current Neuropharmacology

Panglial Gap Junctional Communication is Essential for Maintenance of Myelin in the CNS

(2012) O. Tress et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Melatonin dysregulation, sleep disturbances and fatigue in multiple sclerosis

(2011) Lena Melamud et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Emerging concepts in autoimmune encephalomyelitis beyond the CD4/TH1 paradigm

(2010) Helena Batoulis et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Central nervous system: cholesterol turnover, brain development and neurodegeneration

(2009) John M. Dietschy   BIOLOGICAL CHEMISTRY

The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking

(2009) Johannes Hirrlinger et al.   BRAIN RESEARCH REVIEWS

A modern approach to the treatment of mitochondrial disease

(2009) Sumit Parikh et al.   Current Treatment Options in Neurology

Melatonin Promotes Oligodendroglial Maturation of Injured White Matter in Neonatal Rats

(2009) Paul Olivier et al.   PLoS One

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Agomelatine, a melatonin receptor agonist with 5-HT2C receptor antagonist properties, protects the developing murine white matter against excitotoxicity

(2008) Pierre Gressens et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Parameters related to lipid metabolism as markers of myelination in mouse brain

(2003) Evan D. Muse et al.   JOURNAL OF NEUROCHEMISTRY