HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design

(2018) William F. Porto et al.   Nature Communications

Prediction of Cell-Penetrating Potential of Modified Peptides Containing Natural and Chemically Modified Residues

(2018) Vinod Kumar et al.   Frontiers in Microbiology

Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds

(2018) Anja Pfalzgraff et al.   Frontiers in Pharmacology

The activity and action mechanism of novel short selective LL-37-derived anticancer peptides against clinical isolates of Escherichia coli

(2018) Hossein Aghazadeh et al.   Chemical Biology & Drug Design

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response

(2017) Mehdi Morchikh et al.   MOLECULAR CELL

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

(2017) Tanja Florin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications

(2017) Berthony Deslouches et al.   Oncotarget

The Anticancer Peptide TAT-RasGAP317−326 Exerts Broad Antimicrobial Activity

(2017) Mathieu Heulot et al.   Frontiers in Microbiology

Synthetic antibiofilm peptides

(2016) César de la Fuente-Núñez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan

(2016) Luz N. Irazazabal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pyrrhocoricin, a proline-rich antimicrobial peptide derived from insect, inhibits the translation process in the cell-free Escherichia coli protein synthesis system

(2016) Masayuki Taniguchi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Efficacy of Antibacterial Peptides Against Peptide-Resistant MRSA Is Restored by Permeabilization of Bacteria Membranes

(2016) Joshua Ravensdale et al.   Frontiers in Microbiology

Non-Membrane Permeabilizing Modes of Action of Antimicrobial Peptides on Bacteria

(2015) Marco Scocchi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy

(2015) Shu Hui Neo et al.   Oncotarget

Novel Antimicrobial Peptides with High Anticancer Activity and Selectivity

(2015) Hung-Lun Chu et al.   PLoS One

Engineering Persister-Specific Antibiotics with Synergistic Antimicrobial Functions

(2014) Nathan W. Schmidt et al.   ACS Nano

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

(2014) Wenyi Li et al.   AMINO ACIDS

A Broad-Spectrum Antibiofilm Peptide Enhances Antibiotic Action against Bacterial Biofilms

(2014) Fany Reffuveille et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Adaptive Evolution of Escherichia coli to an α-Peptide/β-Peptoid Peptidomimetic Induces Stable Resistance

(2013) Line Hein-Kristensen et al.   PLoS One

HEXIM1 Induces Differentiation of Human Pluripotent Stem Cells

(2013) Vanessa Ding et al.   PLoS One

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

(2013) Fernanda Guilhelmelli et al.   Frontiers in Microbiology

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis

(2012) W Ketchart et al.   ONCOGENE

CPPsite: a curated database of cell penetrating peptides

(2012) A. Gautam et al.   Database-The Journal of Biological Databases and Curation

Ctriporin, a New Anti-Methicillin-Resistant Staphylococcus aureus Peptide from the Venom of the Scorpion Chaerilus tricostatus

(2011) Zheng Fan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ubiquitination of HEXIM1 by HDM2

(2011) Joanne Lau et al.   CELL CYCLE

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action

(2011) Marco Scocchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multiresistant Gram-negative infections: a global perspective

(2010) Jennifer Ho et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell-Penetrating Peptides

(2009) H.D. Herce et al.   BIOPHYSICAL JOURNAL

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Nucleophosmin Interacts with HEXIM1 and Regulates RNA Polymerase II Transcription

(2008) Meera Gurumurthy et al.   JOURNAL OF MOLECULAR BIOLOGY

Studies on anticancer activities of antimicrobial peptides

(2007) David W. Hoskin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES