A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1G93A Rats

The multi-dimensional roles of astrocytes in ALS

(2018) Koji Yamanaka et al.   NEUROSCIENCE RESEARCH

Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease

(2018) Amaya Rando et al.   Stem Cell Research & Therapy

Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis

(2018) Kallol Dutta et al.   EXPERIMENTAL NEUROLOGY

Distinct roles for motor neuron autophagy early and late in the SOD1G93Amouse model of ALS

(2017) Noam D. Rudnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adipose-derived stem cell exosomes alleviate pathology of amyotrophic lateral sclerosis in vitro

(2016) Mijung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis

(2016) Akshata A. Almad et al.   GLIA

Recent advances in amyotrophic lateral sclerosis

(2016) Nilo Riva et al.   JOURNAL OF NEUROLOGY

Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS

(2016) Nathan P. Staff et al.   NEUROLOGY

Autophagic down-regulation in motor neurons remarkably prolongs the survival of ALS mice

(2016) Kuo-Wei Hsueh et al.   NEUROPHARMACOLOGY

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

(2016) Yasushi Ito et al.   SCIENCE

Safety and Clinical Effects of Mesenchymal Stem Cells Secreting Neurotrophic Factor Transplantation in Patients With Amyotrophic Lateral Sclerosis

(2016) Panayiota Petrou et al.   JAMA Neurology

NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

(2015) Sonja Johann et al.   GLIA

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

(2015) E. T. Cirulli et al.   SCIENCE

Phase I Trial of Repeated Intrathecal Autologous Bone Marrow-Derived Mesenchymal Stromal Cells in Amyotrophic Lateral Sclerosis

(2015) Ki-Wook Oh et al.   Stem Cells Translational Medicine

Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

(2015) Christine V. Fontanilla et al.   Scientific Reports

Human mesenchymal stromal cell transplantation modulates neuroinflammatory milieu in a mouse model of amyotrophic lateral sclerosis

(2014) Marina Boido et al.   CYTOTHERAPY

Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS

(2014) Diane B. Re et al.   NEURON

Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis

(2014) Ashley E. Frakes et al.   NEURON

SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology

(2014) Rosie K. A. Bunton-Stasyshyn et al.   NEUROSCIENTIST

Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation

(2014) Fábio G. Teixeira et al.   Stem Cell Reviews and Reports

Biological Markers of Mesenchymal Stromal Cells as Predictors of Response to Autologous Stem Cell Transplantation in Patients With Amyotrophic Lateral Sclerosis: An Investigator-Initiated Trial and In Vivo Study

(2014) Hyun Young Kim et al.   STEM CELLS

Intrathecal Delivery of Mesenchymal Stromal Cells Protects the Structure of Altered Perineuronal Nets in SOD1 Rats and Amends the Course of ALS

(2014) Serhiy Forostyak et al.   STEM CELLS

State of play in amyotrophic lateral sclerosis genetics

(2013) Alan E Renton et al.   NATURE NEUROSCIENCE

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

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(2012) Antonio Uccelli et al.   MOLECULAR MEDICINE

Autologous bone marrow-derived stem cells in amyotrophic lateral sclerosis: A pilot study

(2012) Sudesh Prabhakar et al.   NEUROLOGY INDIA

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

(2010) Nichole A. Reyes et al.   JOURNAL OF CLINICAL INVESTIGATION

The “Dying-Back” Phenomenon of Motor Neurons in ALS

(2010) Michal Dadon-Nachum et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multifaceted deaths orchestrated by mitochondria in neurones

(2009) Phillip Nagley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis

(2009) Cédric Boucherie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice

(2009) Heejaung Kim et al.   NEUROSCIENCE LETTERS

Mesenchymal stem cells: A promising candidate in regenerative medicine

(2008) Ye Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis

(2008) A. Vercelli et al.   NEUROBIOLOGY OF DISEASE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON