Article
Biochemistry & Molecular Biology
Xue-Xia Liu, Ling-Biao Gu, Guang-Jie Zhang, Hua-Min Liu, Ya-Ting Zhang, Kun-Peng Zhang
Summary: This study investigated the cellulase-assisted extraction of Chinese yam polysaccharides and determined the optimal conditions. Three polysaccharide fractions were purified and analyzed, with CYP3 showing the strongest antioxidant activity. Methylation and NMR analysis were used to elucidate the detailed structure of CYP3. The results suggest that CYP3 could be utilized as an antioxidant in food processing, pharmaceuticals, and other applications.
PROCESS BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Linqing Yue, Xiaoxiao Song, Xian Cui, Qi Zhang, Xiaojie Tian, Xiuhua Yang, Qiuhao Wu, Yuhuan Liu, Roger Ruan, Yunpu Wang
Summary: Selenylation Astragalus polysaccharides (Se-APS) were successfully prepared using an optimized microwave-assisted method. The Se-APS exhibited high selenium content and showed improved antioxidant capacities compared to Na2SeO3. The release of selenium from Se-APS was higher in intestinal fluid than in gastric fluid.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Meng Ye, Qi Feng, Ying Jiang, Feng Wang, Xuexia Shi, Xiaobing Yang, Xiangdong Gao, Wei Liu
Summary: The traditional Chinese medicine Notopterygium incisum is commonly used to treat rheumatoid arthritis, and polysaccharides from N. incisum may be its main active components. In this study, a novel polysaccharide named NIP was extracted from N. incisum, which showed potential anti-inflammatory and anti-oxidative stress effects. In vitro and in vivo experiments demonstrated NIP's ability to inhibit inflammatory factors, activate signaling pathways, and restore intestinal flora imbalance, suggesting that NIP could be recommended as a functional food for rheumatoid arthritis.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Medicine, Research & Experimental
Wenlong Zhang, Ning Song, Yuan Gao, Xufeng Xie, Kun Liu, Yongguo Cao, Ningyi Jin
Summary: Leptospirosis, a neglected infectious disease, can cause serious health problems including kidney injury and bleeding disorders. This study found that astragalus polysaccharides (APS), a natural compound, can protect hamsters from acute leptospirosis by enhancing glycolysis.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Guangming Chen, Nan Jiang, Junping Zheng, Haiming Hu, Huabing Yang, Aizhen Lin, Baifei Hu, Hongtao Liu
Summary: In this study, two homogeneous polysaccharides (APS-A1 and APS-B1) were isolated from Astragalus membranaceus and their chemical structures were characterized. APS-A1 had a 1,4-alpha-D-Glcp backbone with a 1,4,6-alpha-D-Glcp branch every ten residues, while APS-B1 was a heteropolysaccharide composed of glucose, galactose, and arabinose. Bioactivity assays showed that both APS-A1 and APS-B1 exhibited potential anti-inflammatory activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Jianmei Yao, Huifang Liu, Chiyu Ma, Lulu Pu, Wen Yang, Zhiwei Lei
Summary: This paper provides insights into the composition, methodological techniques for isolation and extraction, biological activities, and functions of tea polysaccharides (TPSs), as well as their application prospects.
Review
Plant Sciences
Xiangyu Li, Zhili Rao, Zhiqiang Xie, Hu Qi, Nan Zeng
Summary: This review summarizes the extraction and purification methods, structural characteristics, and pharmacological activities of polysaccharides from A. macrocephala, and explores their potential applications.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Neeraj Kumari, Manoj Kumar, Radha, Jose M. Lorenzo, Diksha Sharma, Sunil Puri, Ashok Pundir, Sangram Dhumal, Deep Jyoti Bhuyan, G. Jayanthy, Samy Selim, Basel A. Abdel-Wahab, Deepak Chandran, T. Anitha, Vishal P. Deshmukh, Ravi Pandiselvam, Abhijit Dey, Marisennayya Senapathy, Sureshkumar Rajalingam, Pran Mohankumar, John F. Kennedy
Summary: This review summarizes the various extraction techniques for polysaccharides from onion and garlic, as well as their structural and functional properties. It critically assesses the antioxidant, anticancer, immunomodulatory, antimicrobial, anti-inflammatory, and antidiabetic properties of these polysaccharides. Studies have shown that onion and garlic polysaccharides have potential antioxidant and immunomodulatory effects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Prince Allawadhi, Vishakha Singh, Kannan Govindaraj, Isha Khurana, Lopmudra P. Sarode, Umashanker Navik, Anil Kumar Banothu, Ralf Weiskirchen, Kala Kumar Bharani, Amit Khurana
Summary: Polysaccharides are important biological polymers with diverse applications. Polysaccharide nanoparticles exhibit excellent drug delivery properties and therapeutic effects, making them promising for applications in diabetes, organ fibrosis, and arthritis.
CARBOHYDRATE POLYMERS
(2022)
Article
Biotechnology & Applied Microbiology
Hao Peng, Xiangjin Xv, Xiangwei Cui, Yongxiang Fu, Shuqi Zhang, Guanhao Wang, Xue Chen, Wenlu Song
Summary: Microwave-assisted enzymatic extraction (MAEE) was used to separate polysaccharides from micro-Chlorella. The extraction conditions were optimized using Box-Behnken design and response surface methodology. The optimal condition for extracting crude polysaccharides (CSCP) from Chlorella sp. was found to be at 50 degrees C for 2.3 h with 380 W of microwave power and 0.31% of enzyme dosage. The extraction yield of CSCP reached 0.72% under these conditions. Additionally, the modification conditions with α-amylase were optimized, and the enzyme-modified CSCP showed a typical heteropolysaccharide composition.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Chemistry, Applied
Fei Luan, Xi Peng, Ge Zhao, Jiuseng Zeng, Junbo Zou, Zhili Rao, Yao Liu, Xiumeng Zhang, Hang Ma, Nan Zeng
Summary: Phellinus spp., an important medicinal fungus mushroom cultivated and consumed in East Asia for over 2000 years, has polysaccharides as major bioactive macromolecules with multiple health-promoting effects. While extraction and purification methods, structural characteristics, and pharmacological activities of these polysaccharides have been extensively studied, there is limited knowledge on their structures and bioactivity relationship, toxicologic effects, and pharmacokinetic profile. This review systematically summarizes recent progress in the isolation and purification, chemical structures, bioactivities, and underlying mechanisms of PPs, providing insights for their further development as therapeutic agents and functional foods.
Article
Chemistry, Applied
Hanao Qin, Li Huang, Jianwen Teng, Baoyao Wei, Ning Xia, Ying Ye
Summary: The study found that the polysaccharide content of Pu'er tea increased and the molecular weight decreased after fermentation. Additionally, the polysaccharides in aged Pu'er tea contained more sugars compared to raw Pu'er tea. Research has confirmed that fermentation plays a crucial role in improving the quality and biological activity of Pu'er tea.
Article
Biochemistry & Molecular Biology
Xiao Yang, Juan Dai, Yan Zhong, Xuelin Wei, Mengxia Wu, Yuexin Zhang, Ai Huang, Lijun Wang, YuKun Huang, Chisong Zhang, Xianggui Chen, Hang Xiao
Summary: This study characterized IDF from three sources and found that they have different morphologies and compositions. Carrot IDF showed stronger water holding capacity, enoki mushroom IDF had better glucose adsorption, and oat IDF had stronger cholesterol adsorption. None of the three IDFs significantly inhibited starch digestion.
Article
Acoustics
Yijie Wang, Xiong Xiong, Gangliang Huang
Summary: The extraction, purification, structure, derivatization, and biological activities of maidenhair tree polysaccharides were discussed. Collaborative extraction methods such as ultrasound-assisted extraction and microwave-assisted extraction were used for polysaccharide extraction, with ultrasound-assisted extraction showing higher content and efficiency. The structural characteristics and structure-activity relationship of maidenhair tree polysaccharides were studied to support the further development and utilization of these polysaccharides.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Acoustics
Jiaqi Tan, Pengshan Cui, Shaoqin Ge, Xu Cai, Qian Li, Hongkun Xue
Summary: Polysaccharides were extracted from Cornus officinalis fruit using ultrasound assisted aqueous two-phase extraction. The extraction process was optimized using response surface methodology and artificial neural network. The extracted polysaccharides were further purified and characterized. This study provides a feasible method for efficient extraction and purification of polysaccharides from plant resources.
ULTRASONICS SONOCHEMISTRY
(2022)
