Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site

标题
Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site
作者
关键词
RNA methylation, N6-adenosine-methyltransferases, N-6-methyladenosine, ligand binding, computer-aided design, epitranscriptomics
出版物
Cell Reports
Volume 26, Issue 13, Pages 3762-3771.e5
出版商
Elsevier BV
发表日期
2019-03-26
DOI
10.1016/j.celrep.2019.02.100

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