Article
Oncology
Beatriz Costeira, Francisca Brito da Silva, Filipa Fonseca, Rodrigo Oom, Cristina Costa, Joao Vargas Moniz, Nuno Abecasis, Catarina Rodrigues Santos
Summary: This study retrospectively analyzed data from 1001 breast cancer patients and found that most locoregional recurrence events occurred within the first five years after treatment. However, recurrences continued to occur after this time period with unclear risk factors and impact on survival. Factors associated with locoregional recurrence included metastatic lymph nodes and high histologic grade. Locoregional recurrence was also associated with decreased overall survival.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seo-Youn Choi, Jung Hoon Kim, Sanghyeok Lim, Ji Eun Lee, Hyun Jeong Park, Bora Lee
Summary: By analyzing preoperative CT findings, a prognostic nomogram for gallbladder cancer patients can be established, with different types and invasion statuses influencing prognosis.
EUROPEAN RADIOLOGY
(2021)
Article
Urology & Nephrology
Antoine Jeanne-Julien, Olivier Bouchot, Stephane De Vergie, Julien Branchereau, Marie-Aimee Perrouin-Verbe, Jerome Rigaud
Summary: The study aimed to evaluate the oncological results of inguinal lymph node dissection in penile cancer at our centre. The results showed that inguinal lymph node dissection is an essential part of the treatment for penile cancer, and the lymph node stage is closely associated with recurrence-free survival, specific survival, and overall survival.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Public, Environmental & Occupational Health
Shi-Ping Yang, Ming-Yue Rao, Qing-Shuang Chen, Ping Zhou, Chen-Lu Lian, San-Gang Wu
Summary: This study assessed the causes of death and long-term survival after nasopharyngeal carcinoma (NPC) diagnosis. The results showed that primary NPC remains a significant cause of death even 15 years after diagnosis, while death due to cardiac disease and other causes increased over time. Age, race, and diagnosis time were identified as important factors affecting NPC-specific survival.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Gastroenterology & Hepatology
Moon Young Oh, Hongbeom Kim, Hee Ju Sohn, Seungyeoun Lee, Mirang Lee, Hyeong Seok Kim, Youngmin Han, Wooil Kwon, Jin-Young Jang
Summary: Sequential extended cholecystectomy (SEC) is recommended for patients with T2 gallbladder cancer (GBC) diagnosed after simple cholecystectomy (SC) as it provides better survival outcomes. A time interval of less than 28 days to SEC is associated with improved disease-free survival (DFS). Preoperative CA 19-9 level > 37 U/mL and N1 stage are associated with poorer prognosis.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Anesthesiology
M. F. Ramirez, J. P. Cata
Summary: Surgery remains crucial in cancer treatment, but it comes with risks such as tumor metastasis, accelerated growth of micrometastases, and cancer recurrence. Total intravenous anesthesia and regional anesthesia are thought to improve long-term outcomes by different mechanisms, but there is currently no clear consensus.
BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY
(2021)
Editorial Material
Oncology
Matthew K. Labriola, Daniel J. George
Summary: The five-year follow-up data from the CheckMate-214 trial demonstrates the persistent survival benefit of nivolumab and ipilimumab compared to sunitinib in patients with metastatic renal cell carcinoma. The study highlights the limitations of pretreatment risk stratification, particularly for patients who have a durable response to treatment, and emphasizes the importance of conditional outcomes in guiding clinical practice.
Article
Cell Biology
Naoto Fujiwara, Naoto Kubota, Emilie Crouchet, Bhuvaneswari Koneru, Cesia A. Marquez, Arun K. Jajoriya, Gayatri Panda, Tongqi Qian, Shijia Zhu, Nicolas Goossens, Xiaochen Wang, Shuang Liang, Zhenyu Zhong, Sara Lewis, Bachir Taouli, Myron E. Schwartz, Maria Isabel Fiel, Amit G. Singal, Jorge A. Marrero, Austin J. Fobar, Neehar D. Parikh, Indu Raman, Quan-Zhen Li, Masataka Taguri, Atsushi Ono, Hiroshi Aikata, Takashi Nakahara, Hayato Nakagawa, Yuki Matsushita, Ryosuke Tateishi, Kazuhiko Koike, Masahiro Kobayashi, Takaaki Higashi, Shigeki Nakagawa, Yo-ichi Yamashita, Toru Beppu, Hideo Baba, Hiromitsu Kumada, Kazuaki Chayama, Thomas F. Baumert, Yujin Hoshida
Summary: This study analyzed multiple cohorts of NAFLD patients globally to define and validate signatures predictive of long-term HCC risk in NAFLD patients. These signatures can accurately predict the risk of developing HCC in patients and provide assistance for clinical treatment.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Oncology
Lin-Qiang Li, Lei Liang, Li-Yang Sun, Chao Li, Han Wu, Yao-Ming Zhang, Wan-Guang Zhang, Hong Wang, Ya-Hao Zhou, Wei-Min Gu, Ting-Hao Chen, Jie Li, Ying-Jian Liang, Qiu-Ran Xu, Yong-Kang Diao, Hang-Dong Jia, Ming-Da Wang, Cheng-Wu Zhang, Feng Shen, Dong-Sheng Huang, Tian Yang
Summary: This study found that postoperative morbidity following hepatectomy for hepatocellular carcinoma (HCC) is an independent risk factor affecting long-term survival and recurrence. Patients with postoperative morbidity had higher rates of both early and late recurrence compared to those without, and experienced decreased overall survival and time-to-recurrence.
Review
Public, Environmental & Occupational Health
N. Moshina, R. S. Falk, S. Hofvind
Summary: This study aimed to explore the long-term quality of life (QoL) among breast cancer survivors eligible for mammographic screening at diagnosis and compare that to QoL among women with no history of breast cancer. The meta-analysis showed no significant differences in QoL for breast cancer survivors compared with women with no history of breast cancer. The findings suggest that there is no significant difference in QoL between breast cancer survivors and women without a history of breast cancer.
Article
Clinical Neurology
Sirisha Madhu, Andrew Cherian Thomas, Sarah Shuyun Tang, Liang Shen, Sridharan Alathur Ramakrishnan, Naresh Kumar
Summary: This study investigated the factors influencing readmission-free survival (ReAFS) and found that the time frame, general health status, and characteristics of the primary tumor all play important roles in ReAFS. Understanding these factors can help doctors optimize treatment planning.
WORLD NEUROSURGERY
(2022)
Article
Medicine, General & Internal
Ayesha A. Shaikh, David Michael Williams, Jeffrey Wayne Stephens, Kusuma Boregowda, Maneesh Vasanth Udiawar, David E. Price
Summary: This study retrospectively evaluated 39 patients with pituitary apoplexy (PA) and found that PA is mainly associated with pituitary adenoma. Common clinical presentations of PA were ophthalmoplegia or visual field loss. Both conservative and neurosurgical intervention can lead to hypopituitarism.
POSTGRADUATE MEDICAL JOURNAL
(2023)
Article
Oncology
Filippo Pelizzaro, Alessandro Vitale, Anna Sartori, Andrea Vieno, Barbara Penzo, Francesco Paolo Russo, Anna Chiara Frigo, Edoardo G. Giannini, Manuela Piccinnu, Gian Ludovico Rapaccini, Maria Di Marco, Eugenio Caturelli, Marco Zoli, Rodolfo Sacco, Ciro Celsa, Fabio Marra, Andrea Mega, Maria Guarino, Antonio Gasbarrini, Gianluca Svegliati-Baroni, Francesco Giuseppe Foschi, Andrea Olivani, Alberto Masotto, Pietro Coccoli, Giovanni Raimondo, Francesco Azzaroli, Gianpaolo Vidili, Maurizia Rossana Brunetto, Franco Trevisani, Fabio Farinati
Summary: Surveillance significantly impacts long-term survival in HCC patients, leading to earlier diagnosis and increased potential for curative treatments. Implementing widespread surveillance programs is crucial for improving the prognosis of HCC patients.
Article
Oncology
Gregory J. Nason, Michael A. S. Jewett, Peter J. Bostrom, Hanan Goldberg, Aaron R. Hansen, Philippe L. Bedard, Jeremy Sturgeon, Padraig Warde, Peter Chung, Lynn Anson-Cartwright, Joan Sweet, Eshetu G. Atenafu, Martin O'Malley, Robert J. Hamilton
Summary: Surveillance is a safe and effective strategy for patients who achieve a complete response following chemotherapy for metastatic testis cancer.
EUROPEAN UROLOGY ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Dag Holmberg, Fredrik Mattsson, Shaohua Xie, Eivind Ness-Jensen, Hashem El-Serag, Jesper Lagergren
Summary: This study suggests that discontinuation of long-term use of proton-pump inhibitors may decrease the risk of gastric adenocarcinoma and oesophageal adenocarcinoma. Physicians should consider ceasing prescribing these drugs in patients without continued indication for their use.
JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)