A Convenient Late-Stage Fluorination of Pyridylic C−H Bonds with N -Fluorobenzenesulfonimide

Discovery of pyridine-based agrochemicals by using Intermediate Derivatization Methods

(2016) Ai-Ying Guan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Comprehensive Energetic Scale for Quantitatively Estimating the Fluorinating Potential of N–F Reagents in Electrophilic Fluorinations

(2016) Xiao-Song Xue et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2)

(2016) Rainer E. Martin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Direct photocatalytic fluorination of benzylic C–H bonds with N-fluorobenzenesulfonimide

(2015) Matthew B. Nodwell et al.   CHEMICAL COMMUNICATIONS

Ligand-Enabled Stereoselective β-C(sp3)–H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids

(2015) Ru-Yi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comparative Study of the Limitations and Challenges in Atom-Transfer C–H Oxidations

(2015) Ashley M. Adams et al.   ORGANIC LETTERS

Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)–H Bonds

(2015) Jinmin Miao et al.   ORGANIC LETTERS

Development of a Direct Photocatalytic C–H Fluorination for the Preparative Synthesis of Odanacatib

(2015) Shira D. Halperin et al.   ORGANIC LETTERS

A Convenient Photocatalytic Fluorination of Unactivated CH Bonds

(2014) Shira D. Halperin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Late Stage Benzylic C–H Fluorination with [18F]Fluoride for PET Imaging

(2014) Xiongyi Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocatalyzed Benzylic Fluorination: Shedding “Light” on the Involvement of Electron Transfer

(2014) Steven Bloom et al.   ORGANIC LETTERS

Copper-Catalyzed Aerobic Synthesis of 2-Arylpyridines from Acetophenones and 1,3-Diaminopropane

(2014) Long-Yi Xi et al.   ORGANIC LETTERS

A photocatalyzed aliphatic fluorination

(2014) Steven Bloom et al.   Chemical Science

Manganese-Catalyzed Oxidative Benzylic C-H Fluorination by Fluoride Ions

(2013) Wei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

(2013) Marcus Baumann et al.   Beilstein Journal of Organic Chemistry

Strategies To Reduce hERG K+ Channel Blockade. Exploring Heteroaromaticity and Rigidity in Novel Pyridine Analogues of Dofetilide

(2013) João F. S. Carvalho et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed C–H Activation/Cross-Coupling of Pyridine N-Oxides with Nonactivated Secondary Alkyl Bromides

(2013) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modular Pyridine Synthesis from Oximes and Enals through Synergistic Copper/Iminium Catalysis

(2013) Ye Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Kondrat’eva Reaction in Flow: Direct Access to Annulated Pyridines

(2013) Johannes Lehmann et al.   ORGANIC LETTERS

Iron(II)-Catalyzed Benzylic Fluorination

(2013) Steven Bloom et al.   ORGANIC LETTERS

Metal-Free Fluorination of C(sp3)–H Bonds Using a Catalytic N-Oxyl Radical

(2013) Yuuki Amaoka et al.   ORGANIC LETTERS

Selective C-H Fluorination of Pyridines and Diazines Inspired by a Classic Amination Reaction

(2013) P. S. Fier et al.   SCIENCE

A Polycomponent Metal-Catalyzed Aliphatic, Allylic, and Benzylic Fluorination

(2012) Steven Bloom et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine Transfer to Alkyl Radicals

(2012) Montserrat Rueda-Becerril et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

(2012) Wafa Gati et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

(2012) Adam E. Goetz et al.   Nature Chemistry

Pd-Catalyzed C–H Fluorination with Nucleophilic Fluoride

(2012) Kate B. McMurtrey et al.   ORGANIC LETTERS

Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin

(2012) W. Liu et al.   SCIENCE

Synthesis of Annulated Pyridines by Intramolecular Inverse-Electron-Demand Hetero-Diels-Alder Reaction under Superheated Continuous Flow Conditions

(2011) Rainer E. Martin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ligand-Promoted C3-Selective Arylation of Pyridines with Pd Catalysts: Gram-Scale Synthesis of (±)-Preclamol

(2011) Mengchun Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Catalyzed C-H Functionalization for the Synthesis of Substituted Pyridines

(2011) Yoshiaki Nakao   SYNTHESIS-STUTTGART

Novel tetrahydrochinoline derived CETP inhibitors

(2010) Carsten Schmeck et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Selective C-4 Alkylation of Pyridine by Nickel/Lewis Acid Catalysis

(2010) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines

(2009) Hong Lin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS