期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 7, 页码 2592-2595出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201511276
关键词
bioactivity; ionic self-assembly; multivalent nanofibers; polyoxometalates; short peptides
资金
- NSFC [21573091]
- National Basic Research Program [2013CB834503]
- Sci-Tech development project of Jilin Province [20130522133JH]
Multivalent peptide nanofibers have attracted intense attention as promising platforms, but the fabrication of those nanofibers is mainly dependent on the spontaneous assembly of beta-sheet peptides. Herein we report an alternative approach to the creation of nanofibers: the polyoxometalatedriven self-assembly of short peptides. The resultant nanofibers with concentrated positive charges are excellent multivalent ligands for binding with bacterial cells and thus lead to a salient improvement in bioactivity.
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