Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

Structural basis for histone H2B deubiquitination by the SAGA DUB module

(2016) M. T. Morgan et al.   SCIENCE

Convergent Versus Sequential Protein Synthesis: The Case of Ubiquitinated and Glycosylated H2B

(2015) Mallikanti Seenaiah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of the Protein Semisynthesis Strategy to the Generation of Modified Chromatin

(2015) Matthew Holt et al.   Annual Review of Biochemistry

Chemical Protein Synthesis Using a Second-Generation N-Acylurea Linker for the Preparation of Peptide-Thioester Precursors

(2015) Juan B. Blanco-Canosa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptideo-Aminoanilides as Crypto-Thioesters for Protein Chemical Synthesis

(2014) Jia-Xing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Writing and reading H2B monoubiquitylation

(2014) Gilad Fuchs et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Histones: At the Crossroads of Peptide and Protein Chemistry

(2014) Manuel M. Müller et al.   CHEMICAL REVIEWS

The U4/U6 Recycling Factor SART3 Has Histone Chaperone Activity and Associates with USP15 to Regulate H2B Deubiquitination

(2014) Lindsey Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation

(2014) Harihar Basnet et al.   NATURE

One-pot native chemical ligation of peptide hydrazides enables total synthesis of modified histones

(2014) Jiabin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Convergent Chemical Synthesis of Histone H2B Protein for the Site-Specific Ubiquitination at Lys34

(2013) Peter Siman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The n-SET Domain of Set1 Regulates H2B Ubiquitylation-Dependent H3K4 Methylation

(2013) Jaehoon Kim et al.   MOLECULAR CELL

Highly efficient one-pot ligation and desulfurization

(2013) Tal Moyal et al.   Chemical Science

Systematic Identification of Proteins Binding to Chromatin-Embedded Ubiquitylated H2B Reveals Recruitment of SWI/SNF to Regulate Transcription

(2013) Efrat Shema-Yaacoby et al.   Cell Reports

N-Methylation of Isopeptide Bond as a Strategy to Resist Deubiquitinases

(2012) Mahmood Haj-Yahya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

(2012) Gilad Fuchs et al.   MOLECULAR CELL

Chemical and semisynthesis of posttranslationally modified proteins

(2012) Peter Siman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chemical Approaches To Understand the Language of Histone Modifications

(2011) Abhinav Dhall et al.   ACS Chemical Biology

A Reversible Protection Strategy To Improve Fmoc-SPPS of Peptide Thioesters by the N-Acylurea Approach

(2011) Santosh K. Mahto et al.   CHEMBIOCHEM

Chemical Synthesis and Expression of the HIV-1 Rev Protein

(2011) Peter Siman et al.   CHEMBIOCHEM

Preparation of Fully Synthetic Histone H3 Reveals That Acetyl-Lysine 56 Facilitates Protein Binding Within Nucleosomes

(2011) John C. Shimko et al.   JOURNAL OF MOLECULAR BIOLOGY

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

(2011) Lipeng Wu et al.   MOLECULAR CELL

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

(2010) Champak Chatterjee et al.   Nature Chemical Biology

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

N-Methylcysteine-mediated total chemical synthesis of ubiquitin thioester

(2010) Lesly A. Erlich et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module

(2010) N. L. Samara et al.   SCIENCE

Structure–Activity Analysis of Semisynthetic Nucleosomes: Mechanistic Insights into the Stimulation of Dot1L by Ubiquitylated Histone H2B

(2009) Robert K. McGinty et al.   ACS Chemical Biology

Semisynthesis of a Homogeneous Glycoprotein Enzyme: Ribonuclease C: Part 2

(2009) Christian Piontek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

(2008) Juan B. Blanco-Canosa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

(2008) Robert K. McGinty et al.   NATURE