Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine
出版年份 2019 全文链接
标题
Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-03-29
DOI
10.1038/s41467-019-09474-6
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cellular Handling of Protein Aggregates by Disaggregation Machines
- (2018) Axel Mogk et al. MOLECULAR CELL
- Allostery and molecular machines
- (2018) George H. Lorimer et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Effect of ligand binding on a protein with a complex folding landscape
- (2018) Hisham Mazal et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Direct observation of ultrafast large-scale dynamics of an enzyme under turnover conditions
- (2018) Haim Yuval Aviram et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate
- (2018) Jose Angel Fernández-Higuero et al. Scientific Reports
- Electrostatic interactions between middle domain motif-1 and the AAA1 module of the bacterial ClpB chaperone are essential for protein disaggregation
- (2018) Saori Sugita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
- (2017) Stephanie N. Gates et al. SCIENCE
- Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control
- (2017) Marta Carroni et al. eLife
- Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase
- (2017) Célia Deville et al. Science Advances
- Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes
- (2016) Andrija Finka et al. Annual Review of Biochemistry
- Protein Allostery and Conformational Dynamics
- (2016) Jingjing Guo et al. CHEMICAL REVIEWS
- Allosteric Mechanisms in Chaperonin Machines
- (2016) Ranit Gruber et al. CHEMICAL REVIEWS
- Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell
- (2016) Guanghong Wei et al. CHEMICAL REVIEWS
- Photon-by-Photon Hidden Markov Model Analysis for Microsecond Single-Molecule FRET Kinetics
- (2016) Menahem Pirchi et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Conformational footprints
- (2016) Buyong Ma et al. Nature Chemical Biology
- Multidomain structure and correlated dynamics determined by self-consistent FRET networks
- (2016) Björn Hellenkamp et al. NATURE METHODS
- Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation
- (2016) Adam L Yokom et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation
- (2016) Adam L Yokom et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis for the disaggregase activity and regulation of Hsp104
- (2016) Alexander Heuck et al. eLife
- ClpB N-terminal domain plays a regulatory role in protein disaggregation
- (2015) Rina Rosenzweig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ensemble nature of allostery
- (2014) Hesam N. Motlagh et al. NATURE
- Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy
- (2014) Linnea Olofsson et al. Nature Communications
- Head-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregation
- (2014) Marta Carroni et al. eLife
- A Distal Mutation Perturbs Dynamic Amino Acid Networks in Dihydrofolate Reductase
- (2013) David D. Boehr et al. BIOCHEMISTRY
- Alternating-laser excitation: single-molecule FRET and beyond
- (2013) Johannes Hohlbein et al. CHEMICAL SOCIETY REVIEWS
- Protein rescue from aggregates by powerful molecular chaperone machines
- (2013) Shannon M. Doyle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction
- (2013) R. Rosenzweig et al. SCIENCE
- Allostery and the Monod-Wyman-Changeux Model After 50 Years
- (2012) Jean-Pierre Changeux Annual Review of Biophysics
- Disruption of Ionic Interactions between the Nucleotide Binding Domain 1 (NBD1) and Middle (M) Domain in Hsp100 Disaggregase Unleashes Toxic Hyperactivity and Partial Independence from Hsp70
- (2012) Natalia Lipińska et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mapping the road to recovery: The ClpB/Hsp104 molecular chaperone
- (2012) Skye Hodson et al. JOURNAL OF STRUCTURAL BIOLOGY
- Protein activity regulation by conformational entropy
- (2012) Shiou-Ru Tzeng et al. NATURE
- A toolkit and benchmark study for FRET-restrained high-precision structural modeling
- (2012) Stanislav Kalinin et al. NATURE METHODS
- Hsp70 proteins bind Hsp100 regulatory M domains to activate AAA+ disaggregase at aggregate surfaces
- (2012) Fabian Seyffer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A tightly regulated molecular toggle controls AAA+ disaggregase
- (2012) Yuki Oguchi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Theory of the energy transfer efficiency and fluorescence lifetime distribution in single-molecule FRET
- (2012) I. V. Gopich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The elusive middle domain of Hsp104 and ClpB: Location and function
- (2011) Morgan E. DeSantis et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulatory Circuits of the AAA+ Disaggregase Hsp104
- (2011) Titus M. Franzmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric Communication between the Nucleotide Binding Domains of Caseinolytic Peptidase B
- (2011) José Ángel Fernández-Higuero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Application of the Nano-Positioning System to the Analysis of Fluorescence Resonance Energy Transfer Networks
- (2011) Adam Muschielok et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein
- (2011) Menahem Pirchi et al. Nature Communications
- Global Dynamics of Proteins: Bridging Between Structure and Function
- (2010) Ivet Bahar et al. Annual Review of Biophysics
- Coupling of Oligomerization and Nucleotide Binding in the AAA+ Chaperone ClpB
- (2010) Nicolas D. Werbeck et al. BIOCHEMISTRY
- Large conformational changes in proteins: signaling and other functions
- (2010) Barry J Grant et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Disaggregases in 4 dimensions
- (2010) Thomas RM Barends et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Conformational stability of the full-atom hexameric model of the ClpB chaperone fromEscherichia coli
- (2009) Szymon Ziętkiewicz et al. BIOPOLYMERS
- Decoding the Pattern of Photon Colors in Single-Molecule FRET
- (2009) Irina V. Gopich et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Motor Mechanism for Protein Threading through Hsp104
- (2009) Petra Wendler et al. MOLECULAR CELL
- Coupling ATP utilization to protein remodeling by ClpB, a hexameric AAA+ protein
- (2009) Joel R. Hoskins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hidden dynamic allostery in a PDZ domain
- (2009) C. M. Petit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coupling and Dynamics of Subunits in the Hexameric AAA+ Chaperone ClpB
- (2008) Nicolas D. Werbeck et al. JOURNAL OF MOLECULAR BIOLOGY
- Allosteric regulation and catalysis emerge via a common route
- (2008) Nina M Goodey et al. Nature Chemical Biology
- A nano-positioning system for macromolecular structural analysis
- (2008) Adam Muschielok et al. NATURE METHODS
- Single-molecule FRET measures bends and kinks in DNA
- (2008) A. K. Wozniak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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