标题
Improvement of antibody functionality by structure-guided paratope engraftment
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-02-13
DOI
10.1038/s41467-019-08658-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
- (2018) Peter D. Kwong et al. IMMUNITY
- Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
- (2018) Kai Xu et al. NATURE MEDICINE
- Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry
- (2018) Yen-Ting Lai et al. Nature Communications
- A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure
- (2017) Jeong Hyun Lee et al. IMMUNITY
- Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer
- (2017) Qingbo Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
- (2017) Ling Xu et al. SCIENCE
- Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer
- (2017) Qingbo Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation
- (2017) Zizhang Sheng et al. Frontiers in Immunology
- Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency
- (2016) Stylianos Bournazos et al. CELL
- Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity
- (2016) Yaoxing Huang et al. CELL
- Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses
- (2016) M. Gordon Joyce et al. CELL
- Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
- (2016) Mattia Bonsignori et al. CELL
- Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
- (2016) Jinghe Huang et al. IMMUNITY
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
- (2016) R. Kong et al. SCIENCE
- Lessons from HIV-1 vaccine efficacy trials
- (2016) Jean-Louis Excler et al. Current Opinion in HIV and AIDS
- SeqFeatR for the Discovery of Feature-Sequence Associations
- (2016) Bettina Budeus et al. PLoS One
- Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
- (2015) Tongqing Zhou et al. CELL
- Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
- (2015) Xueling Wu et al. CELL
- Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization
- (2015) M. Asokan et al. JOURNAL OF VIROLOGY
- Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies
- (2014) Thomas B. Kepler et al. Cell Host & Microbe
- Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
- (2014) R. S. Rudicell et al. JOURNAL OF VIROLOGY
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
- (2014) Jinghe Huang et al. NATURE
- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
- (2013) Florian Klein et al. CELL
- HIV-1 neutralizing antibodies: understanding nature's pathways
- (2013) John R. Mascola et al. IMMUNOLOGICAL REVIEWS
- Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1
- (2013) Marcella Sarzotti-Kelsoe et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
- (2013) A. deCamp et al. JOURNAL OF VIROLOGY
- IgBLAST: an immunoglobulin variable domain sequence analysis tool
- (2013) Jian Ye et al. NUCLEIC ACIDS RESEARCH
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Antibodies in HIV-1 Vaccine Development and Therapy
- (2013) F. Klein et al. SCIENCE
- Secondary mechanisms of diversification in the human antibody repertoire
- (2013) Bryan S. Briney et al. Frontiers in Immunology
- HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins
- (2012) Y. Li et al. JOURNAL OF VIROLOGY
- Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
- (2012) Barton F. Haynes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses
- (2012) D. R. Burton et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody
- (2011) J. C. Krause et al. mBio
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
- (2009) M. S. Seaman et al. JOURNAL OF VIROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started