A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation

Improving Polymerase Activity with Unnatural Substrates by Sampling Mutations in Homologous Protein Architectures

(2016) Matthew R. Dunn et al.   ACS Chemical Biology

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

(2016) Burcin Akgun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlling Allosteric Networks in Proteins

(2016) Nikolay V. Dokholyan   CHEMICAL REVIEWS

Molecular basis of 5-hydroxytryptophan synthesis in Saccharomyces cerevisiae

(2016) Jiantao Zhang et al.   Molecular BioSystems

One-pot access to l-5,6-dihalotryptophans and l-alknyltryptophans using tryptophan synthase

(2016) Michael J. Corr et al.   TETRAHEDRON

Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C–H Functionalization

(2016) Landon J. Durak et al.   ACS Catalysis

Cationic Mucic Acid Polymer-Based siRNA Delivery Systems

(2015) Dorothy W. Pan et al.   BIOCONJUGATE CHEMISTRY

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation

(2015) Andrew R. Buller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enantioselective Total Synthesis of (−)-Lansai B and (+)-Nocardioazines A and B

(2014) Haoxuan Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Non-natural Olefin Cyclopropanation Catalyzed by Diverse Cytochrome P450s and Other Hemoproteins

(2014) Thomas Heel et al.   CHEMBIOCHEM

Differential Effects of a Mutation on the Normal and Promiscuous Activities of Orthologs: Implications for Natural and Directed Evolution

(2014) Akhil Khanal et al.   MOLECULAR BIOLOGY AND EVOLUTION

The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans

(2014) Duncan R. M. Smith et al.   ORGANIC LETTERS

Allostery and Substrate Channeling in the Tryptophan Synthase Bienzyme Complex: Evidence for Two Subunit Conformations and Four Quaternary States

(2013) Dimitri Niks et al.   BIOCHEMISTRY

Targeted Nanoparticles Assembled via Complexation of Boronic-Acid-Containing Targeting Moieties to Diol-Containing Polymers

(2013) Han Han et al.   BIOCONJUGATE CHEMISTRY

Chemical Tailoring of Teicoplanin with Site-Selective Reactions

(2013) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH

(2013) S. Brinkmann-Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimisation of engineered Escherichia coli biofilms for enzymatic biosynthesis of l-halotryptophans

(2013) Stefano Perni et al.   AMB Express

Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex

(2012) Michael F. Dunn   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Engineering Biofilms for Biocatalysis

(2011) Andreas N. Tsoligkas et al.   CHEMBIOCHEM

Total synthesis and bioactivity of the marine alkaloid pityriacitrin and some of its derivatives

(2011) Puyong Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Allo-network drugs: harnessing allostery in cellular networks

(2011) Ruth Nussinov et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Gene Expression Enabling Synthetic Diversification of Natural Products: Chemogenetic Generation of Pacidamycin Analogs

(2010) Abhijeet Deb Roy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A convenient one-step synthesis of l-aminotryptophans and improved synthesis of 5-fluorotryptophan

(2008) Michael Winn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water

(2008) Abhijeet Deb Roy et al.   CHEMICAL COMMUNICATIONS

Halogenation Strategies In Natural Product Biosynthesis

(2008) Christopher S. Neumann et al.   CHEMISTRY & BIOLOGY

The facile synthesis of a series of tryptophan derivatives

(2008) Georg Blaser et al.   TETRAHEDRON LETTERS