Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway

MicroRNA-185 inhibits the growth and proliferation of osteoblasts in fracture healing by targeting PTH gene through down-regulating Wnt/β -catenin axis: In an animal experiment

(2018) Chang-Jiang Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The emerging role of microRNAs in bone remodeling and its therapeutic implications for osteoporosis

(2018) Qianyun Feng et al.   BIOSCIENCE REPORTS

MicroRNA-451 blockade promotes osteoblastic differentiation and skeletal anabolic effects by promoting YWHAZ-mediated RUNX2 protein stabilization

(2018) Jieen Pan et al.   MedChemComm

Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function

(2018) Prapaporn Jongwattanapisan et al.   Scientific Reports

Mechanisms of microRNA-mediated gene regulation in unicellular model alga Chlamydomonas reinhardtii

(2018) Sulin Lou et al.   Biotechnology for Biofuels

Bone protection by inhibition of microRNA-182

(2018) Kazuki Inoue et al.   Nature Communications

Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis

(2017) Huaiguang Chang et al.   Cell Death & Disease

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

BGN Mutations in X-Linked Spondyloepimetaphyseal Dysplasia

(2016) Sung Yoon Cho et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis

(2016) Li You et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

miR-106b-5p and miR-17-5p suppress osteogenic differentiation by targeting Smad5 and inhibit bone formation

(2016) Tao Fang et al.   EXPERIMENTAL CELL RESEARCH

microRNA-103a Functions as a Mechanosensitive microRNA to Inhibit Bone Formation Through Targeting Runx2

(2015) Bin Zuo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Overview of MicroRNA Biology

(2015) Ashley Mohr et al.   SEMINARS IN LIVER DISEASE

Role of miRNAs in bone and their potential as therapeutic targets

(2014) Kyoung Min Kim et al.   CURRENT OPINION IN PHARMACOLOGY

MicroRNAs regulate bone metabolism

(2013) Xin Zhao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Prevention and treatment of postmenopausal osteoporosis

(2013) Sri Harsha Tella et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis

(2013) Andre J. van Wijnen et al.   Current Osteoporosis Reports

Glycosaminoglycan chains of biglycan promote bone morphogenetic protein-4-induced osteoblast differentiation

(2012) YAPING YE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Osteoblastic γ-Aminobutyric Acid, Type B Receptors Negatively Regulate Osteoblastogenesis toward Disturbance of Osteoclastogenesis Mediated by Receptor Activator of Nuclear Factor κB Ligand in Mouse Bone

(2011) Yoshifumi Takahata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of canonical Wnt signaling by the extracellular matrix component biglycan

(2011) A. D. Berendsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix Protein Biglycan Induces Osteoblast Differentiation through Extracellular Signal-Regulated Kinase and Smad Pathways

(2010) Xiaoyan Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION