DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress

ER stress and Parkinson's disease: Pathological inputs that converge into the secretory pathway

(2016) Gabriela Mercado et al.   BRAIN RESEARCH

Up-regulation of activating transcription factor 4 induces severe loss of dopamine nigral neurons in a rat model of Parkinson’s disease

(2016) Joseph C. Gully et al.   NEUROSCIENCE LETTERS

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease

(2016) I Celardo et al.   Cell Death & Disease

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative Stress

(2014) Mohammad Parsanejad et al.   PLoS One

Translational up-regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress

(2013) Jungwoo Yang et al.   FASEB JOURNAL

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1

(2013) E. Duplan et al.   JOURNAL OF CELL SCIENCE

ATF4 Protects Against Neuronal Death in Cellular Parkinson's Disease Models by Maintaining Levels of Parkin

(2013) X. Sun et al.   JOURNAL OF NEUROSCIENCE

RESP18 is Involved in the Cytotoxicity of Dopaminergic Neurotoxins in MN9D Cells

(2013) Yufang Huang et al.   NEUROTOXICITY RESEARCH

Neuroprotective Function of DJ-1 in Parkinson’s Disease

(2013) Hiroyoshi Ariga et al.   Oxidative Medicine and Cellular Longevity

Monomer DJ-1 and Its N-Terminal Sequence Are Necessary for Mitochondrial Localization of DJ-1 Mutants

(2013) Chinatsu Maita et al.   PLoS One

Inactivation ofPink1Genein VivoSensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes,ParkinorDJ-1

(2012) M. Emdadul Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL

(2012) Haigang Ren et al.   Molecular Neurodegeneration

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease

(2012) M. W. C. Rousseaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans

(2011) Yiyuan Yuan et al.   PLoS One

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

(2010) L Bouman et al.   CELL DEATH AND DIFFERENTIATION

Leucine-Rich Repeat Kinase 2 Is Associated With the Endoplasmic Reticulum in Dopaminergic Neurons and Accumulates in the Core of Lewy Bodies in Parkinson Disease

(2010) Jérémie Vitte et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4-CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

(2010) Z. Galehdar et al.   JOURNAL OF NEUROSCIENCE

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway

(2010) H. Aleyasin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease

(2009) Jeff Blackinton et al.   NEUROSCIENCE LETTERS

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations

(2008) S Zucchelli et al.   CELL DEATH AND DIFFERENTIATION

Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2α

(2008) Genqing Liang et al.   HUMAN MOLECULAR GENETICS

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

(2008) M. P. van der Brug et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating transcription factor 4

(2007) Kurosh Ameri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY