Quorum Sensing Signal Selectivity and the Potential for Interspecies Cross Talk

A comparative study of non-native N -acyl l -homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence

(2018) Michelle E. Boursier et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands

(2018) Christina L. Wysoczynski-Horita et al.   MOLECULAR MICROBIOLOGY

Tools for engineering coordinated system behaviour in synthetic microbial consortia

(2018) Nicolas Kylilis et al.   Nature Communications

Structure–Function Analyses of the N-Butanoyl l-Homoserine Lactone Quorum-Sensing Signal Define Features Critical to Activity in RhlR

(2018) Michelle E. Boursier et al.   ACS Chemical Biology

The PqsE and RhlR proteins are an autoinducer synthase–receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa

(2018) Sampriti Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress in and promise of bacterial quorum sensing research

(2017) Marvin Whiteley et al.   NATURE

Signal Integration in Quorum Sensing Enables Cross-Species Induction of Virulence in Pectobacterium wasabiae

(2017) Rita S. Valente et al.   mBio

Quantifying the strength of quorum sensing crosstalk within microbial communities

(2017) Kalinga Pavan T. Silva et al.   PLoS Computational Biology

The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer

(2017) Sampriti Mukherjee et al.   PLoS Pathogens

Chromobacterium violaceum Pathogenicity: Updates and Insights from Genome Sequencing of Novel Chromobacterium Species

(2017) Juliana H. Batista et al.   Frontiers in Microbiology

Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds

(2016) Michael Zender et al.   ACS Chemical Biology

The Spectrum of Chromobacterium violaceum Infections from a Single Geographic Location

(2016) Yi dan Lin et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

LasR Variant Cystic Fibrosis Isolates Reveal an Adaptable Quorum-Sensing Hierarchy in Pseudomonas aeruginosa

(2016) John B. Feltner et al.   mBio

Quorum sensing control of Type VI secretion factors restricts the proliferation of quorum-sensing mutants

(2016) Charlotte Majerczyk et al.   eLife

Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control inPseudomonas aeruginosa

(2015) Nora R. Eibergen et al.   CHEMBIOCHEM

PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules

(2015) Steffen Lorenz Drees et al.   CHEMISTRY & BIOLOGY

A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone

(2015) Thao T. Truong et al.   JOURNAL OF BACTERIOLOGY

A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design

(2015) Joseph D. Moore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SigMol: repertoire of quorum sensing signaling molecules in prokaryotes

(2015) Akanksha Rajput et al.   NUCLEIC ACIDS RESEARCH

Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat

(2015) Laura M. Filkins et al.   PLoS Pathogens

Cloning Should Be Simple: Escherichia coli DH5α-Mediated Assembly of Multiple DNA Fragments with Short End Homologies

(2015) Maxim Kostylev et al.   PLoS One

Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa

(2014) Joseph D. Moore et al.   CHEMBIOCHEM

Global Analysis of the Burkholderia thailandensis Quorum Sensing-Controlled Regulon

(2014) C. Majerczyk et al.   JOURNAL OF BACTERIOLOGY

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

(2014) Bhagwan Yadav et al.   Scientific Reports

Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application

(2013) Martin Schuster et al.   Annual Review of Microbiology

Design, Synthesis and Biological Evaluation of N-Sulfonyl Homoserine Lactone Derivatives as Inhibitors of Quorum Sensing in Chromobacterium violaceum

(2013) Mingming Zhao et al.   MOLECULES

Acyl-homoserine lactone-dependent eavesdropping promotes competition in a laboratory co-culture model

(2012) Josephine R Chandler et al.   ISME Journal

Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second-Generation Libraries of N-Acylated L-Homoserine Lactones

(2011) Margrith E. Mattmann et al.   CHEMBIOCHEM

Sharing of quorum-sensing signals and role of interspecies communities in a bacterial plant disease

(2011) Taha Hosni et al.   ISME Journal

The virtue of temperance: built-in negative regulators of quorum sensing in Pseudomonas

(2011) Vittorio Venturi et al.   MOLECULAR MICROBIOLOGY

Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor

(2011) M. J. Lintz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quorum Sensing in Bacterial Species that Use Degenerate Autoinducers Can Be Tuned by Using Structurally Identical Non-native Ligands

(2010) Andrew G. Palmer et al.   CHEMBIOCHEM

Acyl-Homoserine Lactone Binding to and Stability of the Orphan Pseudomonas aeruginosa Quorum-Sensing Signal Receptor QscR

(2010) K.-I. Oinuma et al.   JOURNAL OF BACTERIOLOGY

Homeostatic Interplay between Bacterial Cell-Cell Signaling and Iron in Virulence

(2010) Ronen Hazan et al.   PLoS Pathogens

Acyl-homoserine lactone-mediated cross talk among epiphytic bacteria modulates behavior of Pseudomonas syringae on leaves

(2009) Glenn F J Dulla et al.   ISME Journal

Quorum-Sensing Control of Antibiotic Synthesis in Burkholderia thailandensis

(2009) B. A. Duerkop et al.   JOURNAL OF BACTERIOLOGY

LuxR-family 'solos': bachelor sensors/regulators of signalling molecules

(2009) S. Subramoni et al.   MICROBIOLOGY-SGM

A Quorum-Sensing Antagonist Targets Both Membrane-Bound and Cytoplasmic Receptors and Controls Bacterial Pathogenicity

(2009) Lee R. Swem et al.   MOLECULAR CELL

Comparative Analyses ofN-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

(2008) Grant D. Geske et al.   CHEMBIOCHEM

PqsE Functions Independently of PqsR-Pseudomonas Quinolone Signal and Enhances the rhl Quorum-Sensing System

(2008) J. M. Farrow et al.   JOURNAL OF BACTERIOLOGY

Polymicrobial Nature of Chronic Diabetic Foot Ulcer Biofilm Infections Determined Using Bacterial Tag Encoded FLX Amplicon Pyrosequencing (bTEFAP)

(2008) Scot E. Dowd et al.   PLoS One

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa

(2007) Margrith E. Mattmann et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS