Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma
出版年份 2019 全文链接
标题
Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma
作者
关键词
-
出版物
mBio
Volume 10, Issue 1, Pages -
出版商
American Society for Microbiology
发表日期
2019-02-18
DOI
10.1128/mbio.02871-18
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TAK-228 (formerly MLN0128), an investigational oral dual TORC1/2 inhibitor: A phase I dose escalation study in patients with relapsed or refractory multiple myeloma, non-Hodgkin lymphoma, or Waldenström's macroglobulinemia
- (2016) Irene M. Ghobrial et al. AMERICAN JOURNAL OF HEMATOLOGY
- Determination of MLN0128, an investigational antineoplastic agent, in human plasma by LC-MS/MS
- (2016) Sandeep R. Kunati et al. BIOMEDICAL CHROMATOGRAPHY
- Phase II study of dual phosphoinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 in patients with locally advanced or metastatic transitional cell carcinoma
- (2016) Emmanuel Seront et al. BJU INTERNATIONAL
- A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma
- (2016) Maria I. Carlo et al. ONCOLOGIST
- A viral kinase mimics S6 kinase to enhance cell proliferation
- (2016) Aadra Prashant Bhatt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR Inhibitors Block Kaposi Sarcoma Growth by Inhibiting Essential Autocrine Growth Factors and Tumor Angiogenesis
- (2013) D. Roy et al. CANCER RESEARCH
- mTOR kinase structure, mechanism and regulation
- (2013) Haijuan Yang et al. NATURE
- Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics
- (2012) Qingsong Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphatase and Tensin Homolog on Chromosome 10 Is Phosphorylated in Primary Effusion Lymphoma and Kaposi's Sarcoma
- (2011) Debasmita Roy et al. AMERICAN JOURNAL OF PATHOLOGY
- Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
- (2011) Brian Magnuson et al. BIOCHEMICAL JOURNAL
- Rapamycin With Antiretroviral Therapy in AIDS-Associated Kaposi Sarcoma
- (2011) Susan E. Krown et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Rapamycin Blocks Production of KSHV/HHV8: Insights into the Anti-Tumor Activity of an Immunosuppressant Drug
- (2011) Lisa A. Nichols et al. PLoS One
- Understanding pathogenetic aspects and clinical presentation of primary effusion lymphoma through its derived cell lines
- (2010) Antonino Carbone et al. AIDS
- Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas
- (2010) A. P. Bhatt et al. BLOOD
- Rapamycin inhibits mTORC1, but not completely
- (2009) Carson C. Thoreen et al. Autophagy
- Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma
- (2009) P Gasperini et al. LEUKEMIA
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
- mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
- (2008) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells
- (2008) V. A. Morris et al. JOURNAL OF VIROLOGY
- Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial
- (2008) Robert J Motzer et al. LANCET
- Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
- (2008) A. Y. Choo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started