期刊
SYNLETT
卷 30, 期 9, 页码 1008-1014出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1612214
关键词
enantioselective reactions; diarylation; alkenes; nickel catalysis; reductive cross coupling
资金
- '1000-Youth Talents Plan', National Natural Science Foundation of China [21702149]
- Fundamental Research Funds for the Central Universities [2042018kf0012]
A Ni-catalyzed enantioselective reductive diarylation of alkenes through a tandem Heck cyclization/cross coupling of two structurally distinguished aryl bromides is accomplished for the first time. This reaction takes place under very mild conditions with high efficiency and tolerates a variety of functional groups. Thus, it provides a rapid access to various medicinally relevant bis-heterocycles containing all-carbon quaternary centers with very high enantioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据