Article
Oncology
Tom Pampiglione, Manish Chand
Summary: Fluorescence angiography (FA) with indocyanine green (ICG) has become an established technique in colorectal surgery, providing visual representation of perfusion to aid intraoperative decision making. Studies have shown that routine use of FA can reduce the rate of anastomotic leak, but its limitation lies in the inability to quantify perfusion.
SURGICAL ONCOLOGY-OXFORD
(2022)
Review
Gastroenterology & Hepatology
Sara Lauricella, Daniel Peyser, Francesco Maria Carrano, Patricia Sylla
Summary: This paper reviewed the data on the transanal application of indocyanine green fluorescence angiography (ICG-FA) for the intraluminal assessment of colorectal anastomosis. The study found that the intraluminal assessment of colorectal anastomosis with ICG-FA is feasible, safe, and may reduce the incidence of leaks.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Oncology
Akihiro Kondo, Kensuke Kumamoto, Eisuke Asano, Dongping Feng, Hideki Kobara, Keiichi Okano
Summary: This study confirmed the significant reduction in anastomotic leakage (AL) during laparoscopic rectal cancer surgery with the use of indocyanine green (ICG) fluorescence angiography. Changes in the surgical plan based on ICG fluorescence visibility may improve short-term outcomes for rectal cancer patients.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Review
Surgery
Sameh Hany Emile, Sualeh Muslim Khan, Steven D. Wexner
Summary: The use of indocyanine green fluorescence angiography (ICG-FA) for assessing colorectal anastomoses was found to be associated with lower odds of anastomotic leak compared to traditional white light assessment. However, changing the surgical plan based on ICG-FA may increase the risk of anastomotic leak.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Gastroenterology & Hepatology
M. Song, J. Liu, D. Xia, H. Yao, G. Tian, X. Chen, Y. Liu, Y. Jiang, Z. Li
Summary: This systematic review and meta-analysis found that intraoperative use of ICG fluorescence imaging can significantly reduce the anastomotic leak rate in rectal cancer surgery, as well as decrease the overall complication rate and reoperation rate.
TECHNIQUES IN COLOPROCTOLOGY
(2021)
Article
Surgery
Rachel Q. Liu, Ahmad Elnahas, Ephraim Tang, Nawar A. Alkhamesi, Jeffrey Hawel, Abdulaziz Alnumay, Christopher M. Schlachta
Summary: The routine use of ICG-FA for colorectal anastomosis was found to be cost saving and a dominating strategy. However, there is a need for more prospective, randomized controlled trials to improve the quality of evidence.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Biology
Marlies Michi, Max Madu, Henri A. H. Winters, Daniel M. de Bruin, Joost R. van der Vorst, Caroline Driessen
Summary: The evidence on bone perfusion measured with near-infrared fluorescence (NIRF) is limited, and more clinical studies are needed to evaluate its clinical significance.
Article
Surgery
Jun Watanabe, Ichiro Takemasa, Masanori Kotake, Shingo Noura, Kei Kimura, Hirokazu Suwa, Mitsuyoshi Tei, Yoshinao Takano, Koji Munakata, Shuichiro Matoba, Sigeru Yamagishi, Masayoshi Yasui, Takeshi Kato, Atsushi Ishibe, Manabu Shiozawa, Yoshiyuki Ishii, Taichi Yabuno, Toshikatsu Nitta, Shuji Saito, Yusuke Saigusa, Masahiko Watanabe
Summary: This study evaluated the efficacy of ICG-FI in reducing the rate of anastomotic leakage in minimally invasive rectal cancer surgery. The results showed that ICG-FI significantly reduced the rate of anastomotic leakage, indicating its potential clinical application.
Article
Surgery
Robin A. Faber, Floris P. Tange, Hidde A. Galema, Thomas C. Zwaan, Fabian A. Holman, Koen C. M. J. Peeters, Pieter J. Tanis, Cornelis Verhoef, Jacobus Burggraaf, J. Sven D. Mieog, Merlijn Hutteman, Stijn Keereweer, Alexander L. Vahrmeijer, Joost R. van der Vorst, Denise E. Hilling
Summary: This study aimed to identify objective quantified bowel perfusion patterns in patients undergoing colorectal surgery using a standardized imaging protocol. The study found three different perfusion patterns and highlighted the poor-moderate inter-observer agreement of the subjective interpretation of the fluorescence signal. Objective quantification is needed to assess bowel perfusion.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pengfei Li, Jiaqi Liu, Kunshan He, Shipeng Gong, Chongwei Chi, Pan Liu, Guidong Su, Weili Li, Hui Duan, Ping Liu, Jie Tian, Chunlin Chen
Summary: The feasibility and accuracy of near-infrared fluorescence (NIRF) imaging with indocyanine green (ICG) for detecting tumor invasion in cervical cancer was investigated. NIRF imaging enabled objective and accurate identification of tumor invasion during cervical cancer surgery.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Review
Biology
Lauren N. Goncalves, Pim van den Hoven, Jan van Schaik, Laura Leeuwenburgh, Cas H. F. Hendricks, Pieter S. Verduijn, Koen E. A. van der Bogt, Carla S. P. van Rijswijk, Abbey Schepers, Alexander L. Vahrmeijer, Jaap F. Hamming, Joost R. van der Vorst
Summary: This systematic review of near-infrared fluorescence imaging parameters for assessing tissue perfusion demonstrates the heterogeneity of these parameters in their correlation to perfusion, with time-related parameters appearing superior in a clinical setting.
Review
Medicine, General & Internal
Shijun Xia, Wenjiang Wu, Lidan Luo, Lijuan Ma, Linchong Yu, Yue Li
Summary: We conducted a systematic review and meta-analysis to determine the efficacy of indocyanine green fluorescence angiography (ICGFA) in reducing anastomotic leakage after rectal cancer resection. The results showed that the use of ICGFA during surgery decreased the incidence of anastomotic leakage. However, larger multicenter randomized controlled trials are needed for further validation.
FRONTIERS IN MEDICINE
(2023)
Article
Oncology
Gijsbert M. Kalisvaart, Ruben P. J. Meijer, Okker D. Bijlstra, Hidde A. Galema, Wobbe O. de Steur, Henk H. Hartgrink, Cornelis Verhoef, Lioe-Fee de Geus-Oei, Dirk J. Grunhagen, Yvonne M. Schrage, Alexander L. Vahrmeijer, Jos A. van der Hage
Summary: This study assessed the potential and limitations of near-infrared fluorescence imaging with indocyanine green in intraoperative tumor identification of GISTs. The results showed that GISTs typically have similar fluorescence intensity to the surrounding tissue, indicating that intraoperatively administered indocyanine green is currently not suitable for adequate tumor identification.
Article
Surgery
Juan-Carlos Gomez-Rosado, Javier Valdes-Hernandez, Juan Cintas-Catena, Auxiliadora Cano-Matias, Asuncion Perez-Sanchez, Francisco-Javier del Rio-Lafuente, Cristina Torres-Arcos, Yaiza Lara-Fernandez, Luis-Cristobal Capitan-Morales, Fernando Oliva-Mompean
Summary: This study aimed to evaluate the predictive ability of indocyanine green fluorescence angiography in detecting anastomotic leakage in colorectal cancer surgery. The results showed that arterial hypertension and the location of the anastomosis influenced the intensity of fluorescence. Changing the division point should be considered when the fluorescence intensity at the point of section is below a certain level to prevent anastomotic leakage.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Oncology
Yu Sato, Tetsuta Satoyoshi, Kenji Okita, Daisuke Kyuno, Atsushi Hamabe, Koichi Okuya, Toshihiko Nishidate, Emi Akizuki, Masayuki Ishii, Hiro-O Yamano, Shintaro Sugita, Hiroshi Nakase, Tadashi Hasegawa, Ichiro Takemasa
Summary: The study found that ICG fluorescence imaging can only detect the normal parts of lymph nodes, not the cancerous tissues, which is important for developing appropriate strategies for navigation surgery using NIR fluorescence.