Article
Clinical Neurology
Phoebe K. Yu, Jerilynn Radcliffe, H. Gerry Taylor, Raouf S. Amin, Cristina M. Baldassari, Thomas Boswick, Ronald D. Chervin, Lisa M. Elden, Susan L. Furth, Susan L. Garetz, Alisha George, Stacey L. Ishman, Erin M. Kirkham, Christopher Liu, Ron B. Mitchell, S. Kamal Naqvi, Carol L. Rosen, Kristie R. Ross, Jay Shah, Ignacio E. Tapia, Lisa R. Young, David A. Zopf, Rui Wang, Susan Redline
Summary: The relationship between the severity of obstructive sleep apnea and neurobehavioral morbidity is unclear. This study compares the neurobehavioral symptoms of mild sleep-disordered breathing and obstructive sleep apnea, finding that children with mild sleep-disordered breathing have more abnormal executive function scores and higher rates of inattention and hyperactivity compared to children with obstructive sleep apnea.
Article
Critical Care Medicine
Ablo Prudence Wachinou, Corinne Houehanou, Serge Ade, Terence Totah, Mathieu Berger, Geoffroy Solelhac, Salmane Amidou, Attanon Arnauld Fiogbe, Frederic Alovokpinhou, Philipe Lacroix, Pierre-Marie Preux, Pedro Marques-Vidal, Gildas Agodokpessi, Dismand Houinato, Raphael Heinzer
Summary: The study conducted a large-scale evaluation of the prevalence of sleep-disordered breathing and associated factors in a general population in Benin, west Africa. The high prevalence of SDB identified in the study should encourage the development of public health policies to address and manage this condition in African countries.
LANCET RESPIRATORY MEDICINE
(2022)
Article
Anesthesiology
Carolyne Pehora, David Faraoni, Soichiro Obara, Reshma Amin, Brenda Igbeyi, Adel Al-Izzi, Aman Sayal, Aarti Sayal, Conor Mc Donnell
Summary: The study aimed to determine the incidence and risk factors of PRAEs in children with SDB undergoing general anesthesia. Factors associated with PRAEs were identified, suggesting potential for developing a predictive model and improving preoperative risk assessment.
ANESTHESIA AND ANALGESIA
(2021)
Article
Pediatrics
Eduardo Machado Rossi-Monteiro, Laura Rodrigues Sefair, Marcos Correia Lima, Maria Fernanda Lima Nascimento, Daniel Mendes-Pinto, Lukas Anschuetz, Maria Gloria Rodrigues-Machado
Summary: This study aimed to compare cardiovascular parameters between healthy children and those with obstructive sleep-disordered breathing (oSDB), as well as identify predictors of arterial stiffness indices in children with oSDB. Children with oSDB showed higher reflection coefficient and augmentation index compared to controls, indicating increased arterial stiffness. Multiple regression analysis revealed age, female sex, reflection coefficient, and systolic volume as independent predictors of augmentation index, while higher pulse wave velocity was associated with poorer quality of life.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Review
Critical Care Medicine
Salam Zeineddine, James A. Rowley, Susmita Chowdhuri
Summary: Sleep-disordered breathing (SDB) has significant cardiovascular and neurological effects, with supplemental oxygen therapy showing mixed results in improving oxygen saturation and apnea severity compared to positive airway pressure therapy. Further research is needed to clarify the optimal dose and duration of nocturnal supplemental oxygen (NSO) and its combination with PAP in improving cardiovascular, sleep, and cognitive outcomes in SDB patients.
Article
Medicine, General & Internal
Hao Cui, Hartzell Schaff, Virend K. Somers, Rick A. Nishimura, Joseph A. Dearani, Jeffrey B. Geske, Katherine S. King, Steve R. Ommen
Summary: In patients with hypertrophic cardiomyopathy, more than half were found to have sleep-disordered breathing, which was mainly associated with aging, overweight, and male sex. However, sleep-disordered breathing did not impact survival following septal myectomy.
MAYO CLINIC PROCEEDINGS
(2021)
Article
Medicine, General & Internal
Enric Sanchez, Esther Sapina-Beltran, Ricard Gavalda, Ferran Barbe, Gerard Torres, Ariadna Sauret, Mireia Dalmases, Carolina Lopez-Cano, Liliana Gutierrez-Carrasquilla, Marcelino Bermudez-Lopez, Elvira Fernandez, Francisco Purroy, Eva Castro-Boque, Cristina Farras-Salles, Reinald Pamplona, Didac Mauricio, Cristina Hernandez, Rafael Simo, Albert Lecube, ILERVAS Project Collaborators
Summary: The study found that individuals in the prediabetes stage exhibited higher abnormal sleep breathing parameters compared to those with normal glucose metabolism, with a significant increase in apnea events and hypoxemia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Otorhinolaryngology
Tiffany T. Pham, Shanlee M. Davis, Suhong Tong, Khaled A. Campa, Norman R. Friedman, Sarah A. Gitomer
Summary: A retrospective cross-sectional study found a high prevalence of obstructive sleep-disordered breathing (oSDB) in young patients with Turner syndrome (TS), with a four-fold increased risk compared to the general pediatric population. Risk factors for oSDB in TS included adenoid, tonsillar, and inferior turbinate hypertrophy, birthweight, failure to thrive, and older age at the last clinic visit. Screening for oSDB and performing polysomnography in TS patients with associated risk factors and symptoms is crucial due to the potential exacerbation of behavioral problems, neurocognitive deficits, and growth impairment associated with oSDB.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Critical Care Medicine
Ankit Parekh, Thomas M. Tolbert, Anne M. Mooney, Jaime Ramos-Cejudo, Ricardo S. Osorio, Marcel Treml, Simon-Dominik Herkenrath, Winfried J. Randerath, Indu Ayappa, David M. Rapoport
Summary: This study derives an automated breath-by-breath probability of obstruction using hallmarks of upper airway obstruction visible on clinical sleep studies, to assist in determining the type of sleep apnea in individuals. Results show that the breath-by-breath probability of obstruction can reliably predict the overall burden of obstructed breaths in individual subjects.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Environmental Sciences
Junyi Wang, Wanzhou Wang, Wenlou Zhang, Jianli Wang, Yongwei Huang, Zixuan Hu, Yahong Chen, Xinbiao Guo, Furong Deng, Liqiang Zhang
Summary: This study aimed to assess the joint effect of multiple air pollutants on sleep disordered breathing parameters and identify the dominant pollutants. The results showed significant associations between air pollutants and sleep disordered breathing parameters in patients with obstructive sleep apnea (OSA), with PM10 and O3 being the dominant pollutants.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biology
Rosario Statello, Stefano Rossi, Francesco Pisani, Matteo Bonzini, Roberta Andreoli, Agnese Martini, Monica Puligheddu, Pierluigi Cocco, Michele Miragoli
Summary: This study found altered cardiac autonomic regulation in patients with obstructive sleep apnea (OSA) during nighttime and suggested that nighttime HRV could potentially be used as a predictor of sleep breathing disorders. These findings have important clinical implications for the diagnosis and prognosis of OSA.
Article
Medicine, Research & Experimental
Norman R. Friedman, Maxene Meier, Kaitlyn Tholen, Renee Crowder, Regina Hoefner-Notz, Thanh Nguyen, Sarah Derieg, Kristen Campbell, Lisa McLeod
Summary: The study found that children who do not require oxygen beyond 3 hours after surgery and pass a sleep room air challenge are safe for discharge regardless of age, obesity status, asthma diagnosis, and obstructive apnea/hypopnea index. Further research is needed to confirm these findings.
Article
Clinical Neurology
Jasneek Chawla, Margaret-Anne Harris, Robert Black, Marie-Josee Leclerc, Hannah Burns, Karen A. Waters, Anne Bernard, Kurt Lushington, Helen Heussler
Summary: This study compared neurocognitive and behavioral data in preschool children with symptomatic OSA and PS at recruitment, finding no significant differences between the two groups. The study suggests that symptoms and behavioral disturbances should be considered in addition to OAHI when determining the need for treatment.
SLEEP AND BREATHING
(2021)
Article
Clinical Neurology
Francisco Alves de Sousa, Marta Rios Pinho, Ana Nobrega Pinto, Miguel Bebiano Coutinho, Alberto Caldas Afonso, Manuel Ferreira Magalhaes
Summary: Paediatric obstructive sleep disordered breathing (OSDB) has significant effects on cardiovascular physiology and metabolism. This study aimed to estimate the metabolism of paediatric OSDB at rest and during exercise. The results showed that children with OSDB had higher resting heart rate, oxygen consumption, and energy expenditure compared to controls. They also had lower maximal oxygen consumption and energy expenditure during exercise. The increment of oxygen consumption and energy expenditure with exercise was lower in children with OSDB.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Janna R. Raphelson, Kimberly Y. Kreitinger, Atul Malhotra
Summary: Obstructive sleep apnea (OSA) is a common condition with significant neurocognitive and cardiovascular effects. Positive airway pressure (PAP) therapy can help prevent airway collapse and improve oxygen levels, carbon dioxide levels, and sleep quality. While adherence to PAP therapy was once seen as a barrier, in reality, adherence rates are likely higher than commonly believed, with various strategies available to help improve patient adherence.
Article
Clinical Neurology
Yaping Liu, Eemil Partinen, Ngan Yin Chan, Yves Dauvilliers, Yuichi Inoue, Luigi De Gennaro, Giuseppe Plazzi, Courtney J. Bolstad, Michael R. Nadorff, Ilona Merikanto, Bjorn Bjorvatn, Fang Han, Bin Zhang, Ana Suely Cunha, Sergio Mota-Rolim, Damien Leger, Kentaro Matsui, Colin A. Espie, Frances Chung, Charles M. Morin, Mariusz Sieminski, Penzel Thomas, Brigitte Holzinger, Markku Partinen, Yun Kwok Wing
Summary: This study investigated the prevalence and correlates of dream-enactment behaviours during the COVID-19 pandemic and found a higher percentage of dream-enactment behaviours among individuals with COVID-19 and certain risk factors such as young age, male sex, smoking, alcohol consumption, higher physical activity level, nightmares, COVID-19 diagnosis, olfactory impairment, obstructive sleep apnea symptoms, mood, and post-traumatic stress disorder features. Further research is needed to explore the potential neurodegenerative effects of COVID-19.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Ilona Merikanto, Yves Dauvilliers, Frances Chung, Yun Kwok Wing, Luigi De Gennaro, Brigitte Holzinger, Bjorn Bjorvatn, Charles M. Morin, Thomas Penzel, Christian Benedict, Adrijana Koscec Bjelajac, Ngan Yin Chan, Colin A. Espie, Harald Hrubos-Strom, Yuichi Inoue, Maria Korman, Anne-Marie Landtblom, Damien Leger, Kentaro Matsui, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Catia Reis, Juliana Yordanova, Markku Partinen
Summary: An international survey study reveals that post-acute sequelae of COVID-19 symptoms are more prevalent among severe cases and long-lasting sleep problems are at the core of these symptoms. Understanding the importance of sleep-related symptoms has clinical relevance in diagnosing and treating long-COVID.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Anesthesiology
Selena Gong, Dorothy Qian, Sheila Riazi, Frances Chung, Marina Englesakis, Qixuan Li, Ella Huszti, Jean Wong
Summary: This systematic review and meta-analysis examined the association between the FRAIL scale and mortality and postoperative outcomes in older surgical patients. The results showed that frailty was associated with 30-day mortality, 6-month mortality, postoperative complications, and postoperative delirium.
ANESTHESIA AND ANALGESIA
(2023)
Article
Biology
Bjorn Bjorvatn, Ilona Merikanto, Catia Reis, Maria Korman, Adrijana Koscec Bjelajac, Brigitte Holzinger, Luigi De Gennaro, Yun Kwok Wing, Charles M. Morin, Colin A. Espie, Christian Benedict, Anne-Marie Landtblom, Kentaro Matsui, Harald Hrubos-Strom, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Rachel Ngan Yin Chan, Markku Partinen, Yves Dauvilliers, Frances Chung, Ingeborg Forthun
Summary: The present study aimed to investigate the relationship between shift/night work and face-to-face work with the prevalence and severity of COVID-19. The results showed that shift/night work was not associated with an increased risk of COVID-19, but shift/night workers reported more severe disease when infected. Face-to-face work was associated with an increased risk of COVID-19, but not with higher disease severity.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Review
Anesthesiology
Linor Berezin, Mahesh Nagappa, Khashayar Poorzargar, Aparna Saripella, Jennita Ariaratnam, Nina Butris, Marina Englesakis, Frances Chung
Summary: The study aimed to determine the effectiveness of positive airway pressure (PAP) therapy in reducing the risk of postoperative complications in patients with obstructive sleep apnea (OSA) undergoing surgery. The results showed that PAP therapy was associated with a decreased risk of postoperative respiratory complications and unplanned ICU admission in non-cardiac surgery patients with OSA. In patients undergoing cardiac surgery, PAP therapy decreased the risk of postoperative cardiac complications and atrial fibrillation.
JOURNAL OF CLINICAL ANESTHESIA
(2023)
Article
Clinical Neurology
Serena Scarpelli, Alessandra De Santis, Valentina Alfonsi, Maurizio Gorgoni, Charles M. Morin, Colin Espie, Ilona Merikanto, Frances Chung, Thomas Penzel, Bjorn Bjorvatn, Yves Dauvilliers, Brigitte Holzinger, Yun K. Wing, Markku Partinen, Giuseppe Plazzi, Luigi De Gennaro
Summary: Recent investigations have found that COVID-19 patients may continue to experience symptoms for 2-3 months after the onset of the infection. This study examined sleep and dream alterations in patients with long-COVID and identified the factors that contribute to these alterations. The results showed that long-COVID patients had more severe sleep problems compared to short-COVID patients. Additionally, the number of post-acute symptoms and psychological factors were found to be important determinants of sleep and dream alterations in long-COVID individuals.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychiatry
Pei Xue, Ilona Merikanto, Frances Chung, Charles M. Morin, Colin Espie, Bjorn Bjorvatn, Jonathan Cedernaes, Anne-Marie Landtblom, Thomas Penzel, Luigi De Gennaro, Brigitte Holzinger, Kentaro Matsui, Harald Hrubos-Strom, Maria Korman, Damien Leger, Sergio Mota-Rolim, Courtney J. Bolstad, Michael Nadorff, Giuseppe Plazzi, Catia Reis, Rachel Ngan Yin Chan, Yun Kwok Wing, Juliana Yordanova, Adrijana Koscec Bjelajac, Yuichi Inoue, Markku Partinen, Yves Dauvilliers, Christian Benedict
Summary: Short and long sleep duration after receiving mRNA vaccines is associated with a higher risk of post-COVID symptoms. The study suggests that short and long sleepers are more likely to experience prolonged COVID-19 symptoms compared to normal sleepers. Further research is needed to validate these findings in cohorts with confirmed SARS-CoV-2 infection.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Anesthesiology
Ellene Yan, David He, Tarek K. Rajji, Frances Chung
INTERNATIONAL ANESTHESIOLOGY CLINICS
(2023)
Review
Clinical Neurology
Nina Butris, Evan Tang, Bianca Pivetta, David He, Aparna Saripella, Ellene Yan, Marina Englesakis, Mark I. Boulos, Mahesh Nagappa, Frances Chung
Summary: Determining the prevalence and risk factors of sleep disturbances in surgical patients is crucial for risk stratification and perioperative care planning. A systematic review and meta-analysis showed that the overall prevalence of sleep disturbances in these patients was 60%, with high preoperative PSQI scores and anxiety being significant risk factors. Patients with postoperative delirium also had higher rates of pre- and postoperative sleep disturbances. The high prevalence of preoperative sleep disturbances negatively impacts postoperative outcomes and well-being, calling for further research.
SLEEP MEDICINE REVIEWS
(2023)
Article
Cardiac & Cardiovascular Systems
Shashank Shekhar, Roop Kaw, Shivabalan Kathavarayan Ramu, Adam Pampori, Toshiaki Isogai, Amar Krishnaswamy, Rishi Puri, Grant Reed, Serge C. Harb, James Yun, Samir R. Kapadia
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Letter
Cardiac & Cardiovascular Systems
Shashank Shekhar, Roop Kaw, Ankit Agrawal, Toshiaki Isogai, Hassan Lak, Gauranga Mahalwar, Adam Pampori, Grant Reed, Venu Menon, Samir R. Kapadia
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Anesthesiology
Chi Pham, Khashayar Poorzargar, Darshan Panesar, Kang Lee, Jean Wong, Matteo Parotto, Frances Chung
Summary: The study aimed to evaluate the feasibility and accuracy of remote Video Plethysmography (VPPG) for contactless measurements of blood pressure (BP) and heart rate (HR) in adult surgical patients in a hospital setting. An iPad Pro was used to record a 1.5-minute facial video of the participant's face and VPPG was used to extract vital signs measurements. The VPPG BP algorithm showed limitations in capturing individual variations in blood pressure, highlighting the need for further improvements.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2023)
Article
Anesthesiology
Khashayar Poorzargar, Chi Pham, Darshan Panesar, Sheila Riazi, Kang Lee, Matteo Parotto, Frances Chung
Summary: The accurate and contactless measurement of respiratory rate (RR) is crucial for patient care. Video Plethysmography (VPPG) is a novel technology that uses facial video to measure RR without contact. This study showed that VPPG can accurately predict RR in surgical patients, with a success rate of 99.1%.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2023)
Review
Cardiac & Cardiovascular Systems
Roop K. Kaw
Summary: Pulmonary hypertension is a risk factor for perioperative complications after non-cardiac surgery. Limited data and monitoring for patients with pulmonary hypertension undergoing non-cardiac surgery may contribute to higher complication rates and poor outcomes.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Health Care Sciences & Services
Ashish K. Khanna, Marilyn A. Moucharite, Patrick J. Benefield, Roop Kaw
Summary: The purpose of this study was to characterize the medical and surgical patient characteristics, as well as the clinical and economic outcomes, associated with unplanned ICU admissions. The results showed that patients with a higher comorbid burden were more likely to require emergency care and unplanned ICU admissions, leading to increased mortality, longer hospital stays, and higher costs. Therefore, improving care and monitoring of patients outside the ICU is crucial.
CLINICOECONOMICS AND OUTCOMES RESEARCH
(2023)
